CA2138955A1 - Process for making phenylthiomethylpyridinylalkenoates - Google Patents

Process for making phenylthiomethylpyridinylalkenoates

Info

Publication number
CA2138955A1
CA2138955A1 CA002138955A CA2138955A CA2138955A1 CA 2138955 A1 CA2138955 A1 CA 2138955A1 CA 002138955 A CA002138955 A CA 002138955A CA 2138955 A CA2138955 A CA 2138955A CA 2138955 A1 CA2138955 A1 CA 2138955A1
Authority
CA
Canada
Prior art keywords
formula
phenyl
halo
group
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002138955A
Other languages
English (en)
French (fr)
Inventor
Robert A. Daines
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2138955A1 publication Critical patent/CA2138955A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002138955A 1992-06-30 1993-06-30 Process for making phenylthiomethylpyridinylalkenoates Abandoned CA2138955A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90695192A 1992-06-30 1992-06-30
US07/906,951 1992-06-30
US2520093A 1993-03-02 1993-03-02
US08/025,200 1993-03-02
PCT/US1993/006177 WO1994000433A1 (en) 1992-06-30 1993-06-30 Process for making phenylthiomethylpyridinylalkenoates

Publications (1)

Publication Number Publication Date
CA2138955A1 true CA2138955A1 (en) 1994-01-06

Family

ID=26699426

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002138955A Abandoned CA2138955A1 (en) 1992-06-30 1993-06-30 Process for making phenylthiomethylpyridinylalkenoates

Country Status (10)

Country Link
EP (1) EP0649408A4 (OSRAM)
JP (1) JP3181917B2 (OSRAM)
KR (1) KR950702184A (OSRAM)
CN (1) CN1095713A (OSRAM)
AU (1) AU678979B2 (OSRAM)
CA (1) CA2138955A1 (OSRAM)
MX (1) MX9303972A (OSRAM)
NZ (1) NZ254473A (OSRAM)
TW (1) TW247907B (OSRAM)
WO (1) WO1994000433A1 (OSRAM)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1335795A (en) * 1993-12-08 1995-06-27 Smithkline Beecham Corporation Compounds
GB9508137D0 (en) * 1995-04-21 1995-06-07 Smithkline Beecham Plc Formulation
CN1314666C (zh) * 2005-12-19 2007-05-09 华中师范大学 微波辅助合成硫醚类化合物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3810379A1 (de) * 1988-03-26 1989-10-12 Hoechst Ag Azaneophyl- und silazaneophylsulfide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schaedlingsbekaempfungsmittel
HUT64748A (en) 1990-06-07 1994-02-28 Smithkline Beecham Corp Method for producing benzoic acid derivatives and pharmaceutical preparatives containing said compounds
AU7982591A (en) 1990-06-07 1991-12-31 Smithkline Beecham Corporation Amide linked pyridyle-benzoic acid derivatives for treating leukotriene-related diseases
WO1991018601A1 (en) 1990-06-07 1991-12-12 Smithkline Beecham Corporation Benzoic acid derivatives
EP0548291A1 (en) * 1990-09-13 1993-06-30 Smithkline Beecham Corporation Pyridylthio or pyridyloxy alkanoic acids
WO1993006085A1 (en) * 1991-09-19 1993-04-01 Smithkline Beecham Corporation Pyridine compounds for treating leukotriene-related diseases

Also Published As

Publication number Publication date
MX9303972A (es) 1994-04-29
KR950702184A (ko) 1995-06-19
TW247907B (OSRAM) 1995-05-21
JP3181917B2 (ja) 2001-07-03
AU678979B2 (en) 1997-06-19
NZ254473A (en) 1996-11-26
EP0649408A4 (en) 1995-06-21
AU4655793A (en) 1994-01-24
WO1994000433A1 (en) 1994-01-06
CN1095713A (zh) 1994-11-30
JPH07508283A (ja) 1995-09-14
EP0649408A1 (en) 1995-04-26

Similar Documents

Publication Publication Date Title
CA1089860A (en) Pyridinyl-2(1h)-pyridinones and preparation
EP2727910B1 (en) Pyridin-2-yl-thiourea and Pyridin-2-yl-amine derivatives as intermediates for the preparation of Pyridin-2yl-amino-1,2,4-thiadiazole glucokinase activators
CN112739689B (zh) 含氟嘧啶化合物及其制造方法
CA1179350A (en) Pyridyl(oxy/thio)phenoxy compounds, herbicidal compositions and methods
CA1093080A (en) 2-substituted-5-trifluoromethylpyridine compounds and process for preparation thereof
CS183291A3 (en) Process for preparing substituted and unsubstituted 2,3-pyridine carboxylate
US6635765B2 (en) Processes for preparing torsemide intermediate
GB1599122A (en) 2-phenoxy-5-trifluoromethylpyridine compounds and their use in the production of herbicides
CN117384089A (zh) 一种可用于蛋白质半胱氨酸残基可逆化学修饰的探针及其制备方法
JPH04230262A (ja) ピリジン−２，３−ジカルボン酸ジアルキルの製法
AU2001247592A1 (en) Novel processes for preparing torsemide intermediate
WO1983004253A1 (en) Process for the preparation of 2-(5,5-disubstituted-4-oxo-2-imidazolin-2-yl)-nicotinic, quinoline-3-carboxylic and benzoic acids
JP2970923B2 (ja) ｏ―カルボキシピリジル―およびｏ―カルボキシキノリルイミダゾリノンの改良製造法
WO2009148195A1 (en) 5-(4-hydroxybenzyl)thiazolidine-2,4-dione as intermediate for synthesis of thiazolidinedione based compounds and process for preparing the same
CA2685047A1 (en) Process for preparing 2-(2-pyridylmethyl)sulphinyl-1h-benzimidazoles and intermediate compounds used therein
EP0649408A1 (en) Process for making phenylthiomethylpyridinylalkenoates
US10287287B2 (en) Process development of a pyridine-containing NK-1 receptor antagonist
US20130065911A1 (en) N-(5-cycloalkyl- or 5-heterocyclyl-)-pyridin-3-yl carboxamides
JP2719604B2 (ja) フッ素置換ピリジン誘導体
WO2004000810A1 (en) A process for the production of substituted phenyl ethers
JPS58154561A (ja) ２−ヒドロキシハロゲノピリジンの製造方法
US2422619A (en) Vitamin b6 intermediates
JPH05320132A (ja) ２−クロロ−５−クロロメチルピリジン及び／又は２−クロロ−５−ジクロロメチルピリジンの製造方法
CN115141140A (zh) 一种3,5-二氯吡啶的合成方法
JPH08198851A (ja) メチルアミノピリジン誘導体の合成方法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead