CA2136213A1 - Tissus de taxus cultives en tant que source de taxol, taxanes connexes et autres composes antitumoraux et antiviraux - Google Patents
Tissus de taxus cultives en tant que source de taxol, taxanes connexes et autres composes antitumoraux et antivirauxInfo
- Publication number
- CA2136213A1 CA2136213A1 CA002136213A CA2136213A CA2136213A1 CA 2136213 A1 CA2136213 A1 CA 2136213A1 CA 002136213 A CA002136213 A CA 002136213A CA 2136213 A CA2136213 A CA 2136213A CA 2136213 A1 CA2136213 A1 CA 2136213A1
- Authority
- CA
- Canada
- Prior art keywords
- taxol
- taxus
- roots
- cell line
- root
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/04—Plant cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Botany (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88661992A | 1992-05-21 | 1992-05-21 | |
US07/886,619 | 1992-05-21 | ||
PCT/US1993/004424 WO1993023555A1 (fr) | 1992-05-21 | 1993-05-11 | Tissus de taxus mis en culture utilise comme source de taxol, taxanes et autres nouveaux composes antitumoraux/antiviraux apparantes |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2136213A1 true CA2136213A1 (fr) | 1993-11-25 |
Family
ID=25389395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002136213A Abandoned CA2136213A1 (fr) | 1992-05-21 | 1993-05-11 | Tissus de taxus cultives en tant que source de taxol, taxanes connexes et autres composes antitumoraux et antiviraux |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0642586A4 (fr) |
JP (1) | JPH08500973A (fr) |
AU (1) | AU4242993A (fr) |
CA (1) | CA2136213A1 (fr) |
WO (1) | WO1993023555A1 (fr) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7264951B1 (en) | 1992-02-20 | 2007-09-04 | Phyton, Inc. | Enhanced production of taxol and taxanes by cell cultures of Taxus species |
CA2434692A1 (fr) * | 1992-04-07 | 1993-10-08 | Paul M. Cino | Induction de cellules de cal et la preparation de taxanes |
WO1994020606A1 (fr) * | 1993-03-05 | 1994-09-15 | Celex Laboratories Inc. | Culture de tissus vegetaux pour la production de taxol |
KR950005081B1 (ko) * | 1993-07-06 | 1995-05-18 | 산림청임목육종연구소 | 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법 |
DE69435141D1 (de) | 1993-07-19 | 2008-10-30 | Angiotech Pharm Inc | Anti-angiogene Mittel und Verfahren zu deren Verwendung |
DE69426692T2 (de) * | 1993-11-15 | 2001-06-21 | Mitsui Chemicals Inc | Methode zur herstellung von taxan-diterpen und methode zum einten von kulturzellen, die taxan-diterpen in hohen ausbeuten herstellen |
AU716005B2 (en) | 1995-06-07 | 2000-02-17 | Cook Medical Technologies Llc | Implantable medical device |
DK0954596T3 (da) | 1996-05-24 | 2006-05-15 | Phyton Inc | Foröget produktion af taxaner ved celledyrkning af Taxus-art |
WO1998011135A1 (fr) * | 1996-09-12 | 1998-03-19 | Hwang Byung Doo | Proteine ressemblant au taxol (talp) et procede de preparation correspondant |
IL121320A (en) | 1997-02-23 | 2000-12-06 | Ibr Ltd | Extracts from cells or tissue of organisms which are capable of entering dormancy for inhibition of proliferation of target cells or tissue |
WO2002085337A1 (fr) | 2001-04-20 | 2002-10-31 | The University Of British Columbia | Systemes d'administration de medicament micellaire pour medicaments hydrophobes |
CA2307393A1 (fr) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Chimiotherapie par administration d'un ginsenoside |
CA2440935A1 (fr) | 2001-03-13 | 2002-09-19 | Richard Liggins | Vecteurs de delivrance de medicament micellaires, leurs precurseurs et leurs utilisations |
US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
AU2003300076C1 (en) | 2002-12-30 | 2010-03-04 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
EP2390262A1 (fr) | 2003-05-16 | 2011-11-30 | Intermune, Inc. | Ligands de récepteur de chimiokine synthétique et leurs procédés d'utilisation |
US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
US7846940B2 (en) | 2004-03-31 | 2010-12-07 | Cordis Corporation | Solution formulations of sirolimus and its analogs for CAD treatment |
US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
US8691780B2 (en) | 2005-02-17 | 2014-04-08 | The Board Of Trustees Of The Leland Stanford Junior University | Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby |
WO2006129988A1 (fr) | 2005-06-03 | 2006-12-07 | Samyang Genex Corporation | Production de masse de metabolite secondaire dans une culture de cellules vegetales par le traitement de melange a base de saccharides dans un milieu |
CN100393879C (zh) * | 2005-12-26 | 2008-06-11 | 合肥宏源生物技术开发有限公司 | 电穿孔转Ri质粒诱发红豆杉发根的方法 |
CA2922029C (fr) | 2006-03-22 | 2017-11-28 | Medigene Ag | Une combinaison d'une preparation liposomale cationique renfermant un agent antimitotique et une preparation non liposomale renfermant un agent antimitotique |
ATE519511T1 (de) | 2006-06-30 | 2011-08-15 | Cook Inc | Verfahren zur herstellung und modifizierung von taxan-beschichtungen für implantierbare medizinische vorrichtungen |
US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
US8273404B2 (en) | 2008-05-19 | 2012-09-25 | Cordis Corporation | Extraction of solvents from drug containing polymer reservoirs |
ES2530462T3 (es) | 2008-05-22 | 2015-03-03 | Galera Therapeutics Llc | Combinación terapia antitumoral |
EP2310507A4 (fr) | 2008-07-08 | 2013-03-20 | David Gladstone Inst | Procédés et compositions de modulation de l'angiogenèse |
US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
US20120302954A1 (en) | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
US20120303115A1 (en) | 2011-05-25 | 2012-11-29 | Dadino Ronald C | Expandable devices coated with a rapamycin composition |
US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
EP3539563A1 (fr) | 2012-07-19 | 2019-09-18 | Redwood Bioscience, Inc. | Anticorps spécifique pour cd22 et ses procédés d'utilisation |
EP2916835A4 (fr) | 2012-11-12 | 2016-07-27 | Redwood Bioscience Inc | Composés et procédés pour produire un conjugué |
PL2956175T3 (pl) | 2013-02-15 | 2018-05-30 | The Regents Of The University Of California | Chimeryczny receptor antygenowy i sposoby jego zastosowania |
EP2970124B1 (fr) | 2013-03-14 | 2019-05-22 | The Board of Trustees of the Leland Stanford Junior University | Modulateurs de l'aldéhyde déshydrogénase-2 mitochondriale et leurs procédés d'utilisation |
WO2015081282A1 (fr) | 2013-11-27 | 2015-06-04 | Redwood Bioscience, Inc. | Composés hydrazinyl-pyrrolo et procédés de production d'un conjugué |
EP3107899B1 (fr) | 2014-02-19 | 2020-08-12 | Aviv Therapeutics, Inc. | Amides polycycliques se liant à l'aldéhyde déshydrogénase 2 mitochondriale (aldh2) et leur utilisation pour le traitement du cancer |
AU2016326747A1 (en) | 2015-09-25 | 2018-03-01 | Zy Therapeutics Inc. | Drug formulation based on particulates comprising polysaccharide-vitamin conjugate |
WO2017083637A1 (fr) | 2015-11-12 | 2017-05-18 | The Board Of Trustees Of The Leland Stanford Junior University | Oligophosphotriesters riches en guanidinium à pénétration cellulaire pour l'administration de médicament et de sonde |
TWI760319B (zh) | 2015-12-30 | 2022-04-11 | 杏國新藥股份有限公司 | 乳癌治療 |
CN109071634A (zh) | 2016-04-26 | 2018-12-21 | R.P.谢勒技术有限责任公司 | 抗体偶联物及其制备和使用方法 |
EP3463308B1 (fr) | 2016-06-01 | 2021-12-01 | Servier IP UK Limited | Formulations d'oxyde de polyalkylène-asparaginase et leurs procédés de fabrication et d'utilisation |
TW201825087A (zh) | 2017-01-05 | 2018-07-16 | 杏國新藥股份有限公司 | 胰臟癌治療 |
AU2018211081A1 (en) | 2017-01-18 | 2019-07-18 | Bioatla, Inc. | Chimeric antigen receptors against Axl or Ror2 and methods of use thereof |
EP3388082A1 (fr) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Poly-immunothérapie anticancéreuse avec un complexe de cycle pentaaza macrocyclique |
CA3090129A1 (fr) | 2018-01-31 | 2019-08-08 | Galera Labs, Llc | Polytherapie anticancereuse au moyen d'un complexe de type cycle macrocyclique pentaaza et d'un agent anticancereux a base de platine |
US11660266B2 (en) | 2018-04-11 | 2023-05-30 | Ohio State Innovation Foundation | Methods and compositions for sustained release microparticles for ocular drug delivery |
EP3823674A4 (fr) | 2018-07-18 | 2022-12-28 | Manzanita Pharmaceuticals, Inc. | Conjugués pour administrer un agent anticancéreux à des cellules nerveuses, méthodes d'utilisation et leurs procédés de fabrication |
US11529402B2 (en) | 2019-01-14 | 2022-12-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
US11685904B2 (en) | 2019-02-14 | 2023-06-27 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
CN113692413A (zh) | 2019-04-02 | 2021-11-23 | 肯乔克蒂生物技术股份有限公司 | 外排泵-癌症抗原多特异性抗体以及与其相关的组合物、试剂、试剂盒和方法 |
WO2021033779A1 (fr) * | 2019-08-22 | 2021-02-25 | 北海道三井化学株式会社 | Procédé de production de racine chevelue du genre taxus |
CA3163805A1 (fr) | 2019-12-12 | 2021-06-17 | Ignite Immunotherapy, Inc. | Virus de la vaccine oncolytique a variants et ses methodes d'utilisation |
JP2023512196A (ja) | 2020-01-29 | 2023-03-24 | ケンジョッケティ バイオテクノロジー,インク. | 抗mdr1抗体およびその使用 |
AU2021283080A1 (en) | 2020-06-04 | 2022-12-15 | Kenjockety Biotechnology, Inc. | ABCG2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
WO2021247426A1 (fr) | 2020-06-04 | 2021-12-09 | Kenjockety Biotechnology, Inc. | Anticorps anti-abcg2 et leurs utilisations |
BR112023000650A2 (pt) | 2020-07-14 | 2023-01-31 | Pfizer | Vírus vaccinia recombinante |
CN116490522A (zh) | 2020-09-02 | 2023-07-25 | 肯乔克蒂生物技术股份有限公司 | 抗abcc1抗体及其应用 |
AU2021380659A1 (en) | 2020-11-13 | 2023-06-01 | Kenjockety Biotechnology, Inc. | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
US11299700B1 (en) | 2021-02-19 | 2022-04-12 | Acequia Biotechnology, Llc | Bioreactor containers and methods of growing hairy roots using the same |
WO2023114658A1 (fr) | 2021-12-13 | 2023-06-22 | Kenjockety Biotechnology, Inc. | Anticorps anti-abcb1 |
WO2023159220A1 (fr) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anticorps anti-cd47 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
FR2629819B1 (fr) * | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
US5019504A (en) * | 1989-03-23 | 1991-05-28 | The United States Of America As Represented By The Secretary Of Agriculture | Production of taxol or taxol-like compounds in cell culture |
ATE146527T1 (de) * | 1991-02-12 | 1997-01-15 | Nippon Steel Corp | Verfahren zur herstellung von taxol mittels taxusspezies-zellkultur |
US5407816A (en) * | 1992-02-20 | 1995-04-18 | Phyton Catalytic, Inc. | Enhanced production of taxol and taxanes by cell cultures of taxus species |
WO1994020606A1 (fr) * | 1993-03-05 | 1994-09-15 | Celex Laboratories Inc. | Culture de tissus vegetaux pour la production de taxol |
-
1993
- 1993-05-11 EP EP93911220A patent/EP0642586A4/fr not_active Withdrawn
- 1993-05-11 JP JP6503690A patent/JPH08500973A/ja active Pending
- 1993-05-11 WO PCT/US1993/004424 patent/WO1993023555A1/fr not_active Application Discontinuation
- 1993-05-11 AU AU42429/93A patent/AU4242993A/en not_active Abandoned
- 1993-05-11 CA CA002136213A patent/CA2136213A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0642586A1 (fr) | 1995-03-15 |
WO1993023555A1 (fr) | 1993-11-25 |
JPH08500973A (ja) | 1996-02-06 |
EP0642586A4 (fr) | 1995-11-29 |
AU4242993A (en) | 1993-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |