AU4242993A - Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds - Google Patents

Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds

Info

Publication number
AU4242993A
AU4242993A AU42429/93A AU4242993A AU4242993A AU 4242993 A AU4242993 A AU 4242993A AU 42429/93 A AU42429/93 A AU 42429/93A AU 4242993 A AU4242993 A AU 4242993A AU 4242993 A AU4242993 A AU 4242993A
Authority
AU
Australia
Prior art keywords
taxus
taxol
cultured
tumor
tissues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42429/93A
Inventor
Richard N Arteca
Enaksha Wickremesinhe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Original Assignee
Penn State Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Research Foundation filed Critical Penn State Research Foundation
Publication of AU4242993A publication Critical patent/AU4242993A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
AU42429/93A 1992-05-21 1993-05-11 Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds Abandoned AU4242993A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88661992A 1992-05-21 1992-05-21
US886619 1992-05-21

Publications (1)

Publication Number Publication Date
AU4242993A true AU4242993A (en) 1993-12-13

Family

ID=25389395

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42429/93A Abandoned AU4242993A (en) 1992-05-21 1993-05-11 Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds

Country Status (5)

Country Link
EP (1) EP0642586A4 (en)
JP (1) JPH08500973A (en)
AU (1) AU4242993A (en)
CA (1) CA2136213A1 (en)
WO (1) WO1993023555A1 (en)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7264951B1 (en) 1992-02-20 2007-09-04 Phyton, Inc. Enhanced production of taxol and taxanes by cell cultures of Taxus species
CA2434692A1 (en) * 1992-04-07 1993-10-08 Paul M. Cino Callus cell induction and the preparation of taxanes
WO1994020606A1 (en) * 1993-03-05 1994-09-15 Celex Laboratories Inc. Plant tissue culture method for taxol production
KR950005081B1 (en) * 1993-07-06 1995-05-18 산림청임목육종연구소 Method for producing taxol and its derivatives from embryo cultures of taxus species
DE69435342D1 (en) 1993-07-19 2011-05-05 Angiotech Pharm Inc Anti-angiogenic agents and methods of use
EP0683232B1 (en) * 1993-11-15 2001-02-14 Mitsui Chemicals, Inc. Process for producing taxane diterpene and method of harvesting cultred cell capable of producing taxane diterpene in high yield
CA2178541C (en) 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
KR20070094867A (en) 1996-05-24 2007-09-21 디에프비 바이오테크 인코포레이티드 Enhanced production of taxanes by cell cultures of taxus species
JP3569290B2 (en) * 1996-09-12 2004-09-22 ビュンドー ハン Taxol-like protein and method for producing the same
IL121320A (en) 1997-02-23 2000-12-06 Ibr Ltd Extracts from cells or tissue of organisms which are capable of entering dormancy for inhibition of proliferation of target cells or tissue
CA2307393A1 (en) 2000-05-01 2001-11-01 The University Of British Columbia Ginsenoside chemotherapy
CA2440935A1 (en) 2001-03-13 2002-09-19 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
NZ529647A (en) 2001-04-20 2007-05-31 Univ British Columbia Micellar drug delivery systems for hydrophobic drugs
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
DE60331367D1 (en) 2002-12-30 2010-04-01 Angiotech Int Ag ACTIVE COMPOSITION OF FAST GELING POLYMERIC COMPOSITION
WO2005016241A2 (en) 2003-05-16 2005-02-24 Intermune, Inc. Synthetic chemokine receptor ligands and methods of use thereof
US7846940B2 (en) 2004-03-31 2010-12-07 Cordis Corporation Solution formulations of sirolimus and its analogs for CAD treatment
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7989490B2 (en) 2004-06-02 2011-08-02 Cordis Corporation Injectable formulations of taxanes for cad treatment
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
WO2006089218A2 (en) 2005-02-17 2006-08-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for modulating angiogenesis
KR100797534B1 (en) 2005-06-03 2008-01-24 주식회사 삼양제넥스 Mass production of secondary metabolite in plant cell culture by treatment of saccharide mixture in medicum
CN100393879C (en) * 2005-12-26 2008-06-11 合肥宏源生物技术开发有限公司 Process of inducing root growing of Chinese yew by electric punching transforming Ri plasmid
CA2922029C (en) 2006-03-22 2017-11-28 Medigene Ag A combination of a cationic liposomal preparation comprising an antimitotic agent and a non-liposomal preparation comprising an antimitotic agent
EP2380606B1 (en) 2006-06-30 2018-03-21 Cook Medical Technologies LLC Methods of manufacturing and modifying taxane coatings for implantable medical devices
US8409601B2 (en) 2008-03-31 2013-04-02 Cordis Corporation Rapamycin coated expandable devices
US8273404B2 (en) 2008-05-19 2012-09-25 Cordis Corporation Extraction of solvents from drug containing polymer reservoirs
US9198893B2 (en) 2008-05-22 2015-12-01 Galera Labs, Llc Combination antitumor therapy
WO2010005850A1 (en) 2008-07-08 2010-01-14 The J. David Gladstone Institutes Methods and compositions for modulating angiogenesis
US8642063B2 (en) 2008-08-22 2014-02-04 Cook Medical Technologies Llc Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
US20120303115A1 (en) 2011-05-25 2012-11-29 Dadino Ronald C Expandable devices coated with a rapamycin composition
US20120302954A1 (en) 2011-05-25 2012-11-29 Zhao Jonathon Z Expandable devices coated with a paclitaxel composition
US9956385B2 (en) 2012-06-28 2018-05-01 The Spectranetics Corporation Post-processing of a medical device to control morphology and mechanical properties
IN2015DN00552A (en) 2012-07-19 2015-06-26 Redwood Bioscience Inc
WO2014074218A1 (en) 2012-11-12 2014-05-15 Redwood Bioscience, Inc. Compounds and methods for producing a conjugate
KR20210147101A (en) 2013-02-15 2021-12-06 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 Chimeric Antigen Receptor and Methods of Use Thereof
CN105358531B (en) 2013-03-14 2017-11-14 利兰-斯坦福大学初级学院的董事会 Mitochondrial aldehyde dehydrogenase-2 modulators and its application method
CN115504924A (en) 2013-11-27 2022-12-23 雷德伍德生物科技股份有限公司 Hydrazino-pyrrolo compounds and methods for forming conjugates
HUE051255T2 (en) 2014-02-19 2021-03-01 Aviv Therapeutics Inc Mitochondrial aldehyde dehydrogenase 2 (aldh2) binding polycyclic amides and their use for the treatment of cancer
KR20180058759A (en) 2015-09-25 2018-06-01 제트와이 테라퓨틱스 인코포레이티드 Pharmaceutical preparations based on microparticles comprising a polysaccharide-vitamin conjugate
EP3373977A4 (en) 2015-11-12 2019-07-17 The Board of Trustees of the Leland Stanford Junior University Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery
TWI760319B (en) 2015-12-30 2022-04-11 杏國新藥股份有限公司 Treatment of breast cancer
CN109071634A (en) 2016-04-26 2018-12-21 R.P.谢勒技术有限责任公司 Antibody coupling matter and its preparation and application
HRP20212027T1 (en) 2016-06-01 2022-04-01 Servier IP UK Limited Formulations of polyalkylene oxide-asparaginase and methods of making and using the same
MX2019008503A (en) 2017-01-18 2019-09-13 F1 Oncology Inc Chimeric antigen receptors against axl or ror2 and methods of use thereof.
EP3388082A1 (en) 2017-04-13 2018-10-17 Galera Labs, LLC Combination cancer immunotherapy with pentaaza macrocyclic ring complex
EP3746085A4 (en) 2018-01-31 2022-03-09 Galera Labs, LLC Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
BR112020020930A2 (en) 2018-04-11 2021-03-02 Ohio State Innovation Foundation drug delivery composition, method for treating an eye disorder and kit
CA3105879A1 (en) 2018-07-18 2020-01-23 Manzanita Pharmaceuticals, Inc. Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof
US11529402B2 (en) 2019-01-14 2022-12-20 Ignite Immunotherapy, Inc. Recombinant vaccinia virus and methods of use thereof
CA3129883A1 (en) 2019-02-14 2020-08-20 Ignite Immunotherapy, Inc. Recombinant vaccinia virus and methods of use thereof
EP3946626A1 (en) 2019-04-02 2022-02-09 Kenjockety Biotechnology, Inc. Efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto
JP7266226B2 (en) * 2019-08-22 2023-04-28 北海道三井化学株式会社 Method for producing hairy roots of Taxus
CA3163805A1 (en) 2019-12-12 2021-06-17 Ignite Immunotherapy, Inc. Variant oncolytic vaccinia virus and methods of use thereof
US20230203156A1 (en) 2020-01-29 2023-06-29 Kenjockety Biotechnology, Inc. Anti-mdr1 antibodies and uses thereof
US20230192902A1 (en) 2020-06-04 2023-06-22 Kenjockety Biotechnology, Inc. Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto
JP2023528416A (en) 2020-06-04 2023-07-04 ケンジョッケティ バイオテクノロジー,インク. Anti-ABCG2 Antibodies and Uses Thereof
MX2023000734A (en) 2020-07-14 2023-02-13 Pfizer Recombinant vaccinia virus.
CN116490522A (en) 2020-09-02 2023-07-25 肯乔克蒂生物技术股份有限公司 anti-ABCC 1 antibodies and uses thereof
WO2022103603A1 (en) 2020-11-13 2022-05-19 Kenjockety Biotechnology, Inc. Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof
US11299700B1 (en) 2021-02-19 2022-04-12 Acequia Biotechnology, Llc Bioreactor containers and methods of growing hairy roots using the same
WO2023114658A1 (en) 2021-12-13 2023-06-22 Kenjockety Biotechnology, Inc. Anti-abcb1 antibodies
WO2023159220A1 (en) 2022-02-18 2023-08-24 Kenjockety Biotechnology, Inc. Anti-cd47 antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
FR2629819B1 (en) * 1988-04-06 1990-11-16 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF BACCATIN III AND DESACETYL-10 BACCATIN III DERIVATIVES
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
WO1992013961A1 (en) * 1991-02-12 1992-08-20 Nippon Steel Corporation Process for producing taxol by cell culture of taxus species
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species
WO1994020606A1 (en) * 1993-03-05 1994-09-15 Celex Laboratories Inc. Plant tissue culture method for taxol production

Also Published As

Publication number Publication date
EP0642586A4 (en) 1995-11-29
EP0642586A1 (en) 1995-03-15
CA2136213A1 (en) 1993-11-25
WO1993023555A1 (en) 1993-11-25
JPH08500973A (en) 1996-02-06

Similar Documents

Publication Publication Date Title
AU4242993A (en) Cultured (taxus) tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
CA2130745A1 (en) Enhanced production of taxol and taxanes by cell cultures of taxus species
AU5425794A (en) Process for the preparation of taxane derivatives, novel taxanes so obtained and antitumour and antileukaemia compositions containing same
CA2167718A1 (en) Synthesis of taxol and its derivatives
AU5115393A (en) Novel derivatives of taxol analogues, preparation thereof and compositions containing them
AU7484896A (en) Isolation and purification of paclitaxel from organic matter containing paclitaxel, cephalomannine and other related taxanes
AU7308696A (en) Intermediates for the hemisynthesis of taxanes and their processes of preparation
AU2064092A (en) Asymmetric synthesis of taxol side chain
CA2158147A1 (en) Anti-Tumor Compounds, Pharmaceutical Compositions, Methods for Preparation Thereof and for Treatment
AU3942893A (en) Total synthesis of taxol
AU3164195A (en) Semi-synthetic taxanes with anti-tumoural activity
GR930300141T1 (en) Taxane derivatives, their preparation and use in oncology
HK1002005A1 (en) Beta-lactams, methods for the preparation of taxanes, and sidechain-bearing taxanes
HUP9901788A3 (en) Enhanced production of taxanes by cell cultures of taxus species
AU4973096A (en) Transfer of taxol from yew tree cuttings into a culture medium over time
AU2239295A (en) Preparation of 10-deacetylbaccatin iii and 7-protected-10-deacetylbaccatin iii derivatives from 10-deacetyl taxol a, 10-deacetyl taxol b, and 10-deacetyl taxol c
AU3139593A (en) Synthesis of taxol in culture
AU4818696A (en) Novel methods for the preparation of taxanes using oxazolidine intermediates
AU1306795A (en) Anticonvulsant pseudofructopyranose sulfamates
IL107555A0 (en) Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
AU5486694A (en) Lactone compound and process of production thereof
AU1656399A (en) Bacterial mass production of taxanes and paclitaxel
AU4075893A (en) Novel taxane derivatives, their preparation and compositions containing same
AU2603797A (en) Process to prepare taxol
AU6478598A (en) Process of converting taxanes into baccatin III and 10-deacetylbaccatin III