CA2128560A1 - Piperazines substituees, leur procede de preparation et les compositions pharmaceutiques les contenant - Google Patents

Piperazines substituees, leur procede de preparation et les compositions pharmaceutiques les contenant

Info

Publication number
CA2128560A1
CA2128560A1 CA002128560A CA2128560A CA2128560A1 CA 2128560 A1 CA2128560 A1 CA 2128560A1 CA 002128560 A CA002128560 A CA 002128560A CA 2128560 A CA2128560 A CA 2128560A CA 2128560 A1 CA2128560 A1 CA 2128560A1
Authority
CA
Canada
Prior art keywords
formula
compound
defined above
compounds
alk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002128560A
Other languages
English (en)
French (fr)
Inventor
Jean-Jacques Godfroid
Aazdine Lamouri
Estera Touboul
Xuan Wang
Pierre Renard
Bruno Pfeiffer
Beatrice Guardiola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2128560A1 publication Critical patent/CA2128560A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002128560A 1993-07-23 1994-07-21 Piperazines substituees, leur procede de preparation et les compositions pharmaceutiques les contenant Abandoned CA2128560A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9309088A FR2707984B1 (fr) 1993-07-23 1993-07-23 Nouvelles pipérazines substituées, leur procédé de préparation et les compositions les contenant.
FR93.09088 1993-07-23

Publications (1)

Publication Number Publication Date
CA2128560A1 true CA2128560A1 (fr) 1995-01-24

Family

ID=9449559

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002128560A Abandoned CA2128560A1 (fr) 1993-07-23 1994-07-21 Piperazines substituees, leur procede de preparation et les compositions pharmaceutiques les contenant

Country Status (14)

Country Link
US (2) US5492912A (enExample)
EP (1) EP0638568B1 (enExample)
JP (1) JPH0753548A (enExample)
AT (1) ATE143955T1 (enExample)
AU (1) AU674759B2 (enExample)
CA (1) CA2128560A1 (enExample)
DE (1) DE69400692T2 (enExample)
DK (1) DK0638568T3 (enExample)
ES (1) ES2095726T3 (enExample)
FR (1) FR2707984B1 (enExample)
GR (1) GR3021770T3 (enExample)
HK (1) HK56697A (enExample)
NZ (1) NZ264062A (enExample)
ZA (1) ZA945423B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883098A (en) * 1993-11-29 1999-03-16 Fujisawa Pharmaceutical Co., Ltd. Piperazine derivatives
FR2757158B1 (fr) * 1996-12-18 1999-04-02 Lipha Nouveaux derives d'acide 4-(1-piperazinyl) benzoique, leur procede de preparation et leurs applications therapeutiques
FR2763334A1 (fr) * 1997-05-13 1998-11-20 Lipha Derives anthraniliques
AU2003257418A1 (en) 2002-06-19 2004-01-06 Solvay Pharmaceuticals Gmbh Medicament for the treatment of diseases requiring inhibition or a reduction in the activity of ph value-regulating bicarbonate transporter proteins
FR2846656B1 (fr) * 2002-11-05 2004-12-24 Servier Lab Nouveaux derives d'imidazopyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2920856C (en) 2013-08-09 2026-03-03 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP7177495B2 (ja) * 2016-09-21 2022-11-24 ベクタス・バイオシステムズ・リミテッド 高血圧症及び／又は線維症を処置するための組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE485737A (enExample) * 1947-11-12
CH506548A (de) * 1966-08-10 1971-04-30 Serono Ist Farm Verfahren zur Herstellung von 2-aminsubstituiertem 4,5-Diphenyl-Oxazol
EP0257102B1 (en) * 1986-02-24 1997-11-19 Mitsui Petrochemical Industries, Ltd. Agents for treating neurophathy
US5091428A (en) * 1987-04-24 1992-02-25 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
EP0324520A3 (en) * 1988-01-14 1990-08-16 Merck & Co. Inc. Alkyl-piperazinyl-5-6-alkylenepyrimidines

Also Published As

Publication number Publication date
ATE143955T1 (de) 1996-10-15
AU674759B2 (en) 1997-01-09
ZA945423B (en) 1995-03-01
HK56697A (en) 1997-05-09
ES2095726T3 (es) 1997-02-16
EP0638568B1 (fr) 1996-10-09
DE69400692D1 (de) 1996-11-14
DE69400692T2 (de) 1997-05-07
US5492912A (en) 1996-02-20
AU6860594A (en) 1995-02-02
US5500426A (en) 1996-03-19
EP0638568A1 (fr) 1995-02-15
DK0638568T3 (enExample) 1997-03-24
FR2707984B1 (fr) 1995-09-01
JPH0753548A (ja) 1995-02-28
GR3021770T3 (en) 1997-02-28
NZ264062A (en) 1995-04-27
FR2707984A1 (fr) 1995-01-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued