CA2095013A1 - Rat thyrotropin receptor gene and uses thereof - Google Patents

Rat thyrotropin receptor gene and uses thereof

Info

Publication number
CA2095013A1
CA2095013A1 CA 2095013 CA2095013A CA2095013A1 CA 2095013 A1 CA2095013 A1 CA 2095013A1 CA 2095013 CA2095013 CA 2095013 CA 2095013 A CA2095013 A CA 2095013A CA 2095013 A1 CA2095013 A1 CA 2095013A1
Authority
CA
Canada
Prior art keywords
receptor
antibody
rat
substantially pure
thyrotropin receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2095013
Other languages
English (en)
French (fr)
Inventor
Takashi Akamizu
Shoichiro Ikuyama
Motoyasu Saji
Shinji Kosugi
Toshiaki Ban
Leonard D. Kohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Energy
Government of the United States of America
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2095013A1 publication Critical patent/CA2095013A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA 2095013 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof Abandoned CA2095013A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/006533 WO1992008726A1 (en) 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof

Publications (1)

Publication Number Publication Date
CA2095013A1 true CA2095013A1 (en) 1992-05-16

Family

ID=22221148

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2095013 Abandoned CA2095013A1 (en) 1990-11-15 1990-11-15 Rat thyrotropin receptor gene and uses thereof

Country Status (3)

Country Link
EP (1) EP0557273A1 (show.php)
CA (1) CA2095013A1 (show.php)
WO (1) WO1992008726A1 (show.php)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05504683A (ja) * 1989-12-20 1993-07-22 ニコルス　インスティテュート　ダイアグノスティックス 組み換えチロトロピン受容体
JP2000512280A (ja) * 1996-06-05 2000-09-19 ラポポート，バジル ヒト甲状腺刺激ホルモンレセプター組成物およびその使用
GB2376016A (en) * 2001-05-30 2002-12-04 Nadir R Farid Thyrotropin receptor (TSHR) domain cleavage catalysed by the metalloprotease ADAM 10

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472508A (en) * 1982-12-30 1984-09-18 The Beth Israel Hospital Association Test for detecting and measuring the graves' disease-specific immunoglobulins
US4609622A (en) * 1983-05-31 1986-09-02 Interthyr Research Foundation Inc. Clinical determination and/or quantification of thyrotropin and a variety of thyroid stimulatory or inhibitory factors performed in vitro with an improved thyroid cell line, FRTL-5
US4973578A (en) * 1988-03-17 1990-11-27 Mayo Foundation For Medical Education And Research Synthetic peptides derived from the alpha-subunit of human lycoprotein hormones

Also Published As

Publication number Publication date
EP0557273A4 (show.php) 1994-01-12
EP0557273A1 (en) 1993-09-01
WO1992008726A1 (en) 1992-05-29

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Legal Events

Date Code Title Description
FZDE Dead