CA2087902C - Compositions liposomiques renfermant des photosensibilisateurs a base de porphyrine - Google Patents
Compositions liposomiques renfermant des photosensibilisateurs a base de porphyrine Download PDFInfo
- Publication number
- CA2087902C CA2087902C CA 2087902 CA2087902A CA2087902C CA 2087902 C CA2087902 C CA 2087902C CA 2087902 CA2087902 CA 2087902 CA 2087902 A CA2087902 A CA 2087902A CA 2087902 C CA2087902 C CA 2087902C
- Authority
- CA
- Canada
- Prior art keywords
- porphyrin
- bpd
- formulation according
- liposomal
- liposomal formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83254292A | 1992-02-05 | 1992-02-05 | |
US07/832,542 | 1992-02-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2087902A1 CA2087902A1 (fr) | 1993-08-06 |
CA2087902C true CA2087902C (fr) | 2006-10-17 |
Family
ID=25261954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA 2087902 Expired - Lifetime CA2087902C (fr) | 1992-02-05 | 1993-01-22 | Compositions liposomiques renfermant des photosensibilisateurs a base de porphyrine |
Country Status (11)
Country | Link |
---|---|
US (1) | US6074666A (fr) |
EP (1) | EP0569113B1 (fr) |
JP (1) | JP3020372B2 (fr) |
KR (1) | KR970007303B1 (fr) |
AT (1) | ATE151984T1 (fr) |
CA (1) | CA2087902C (fr) |
DE (1) | DE69310014T2 (fr) |
DK (1) | DK0569113T3 (fr) |
ES (1) | ES2100452T3 (fr) |
GR (1) | GR3023906T3 (fr) |
MX (1) | MX9300560A (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6890555B1 (en) * | 1992-02-05 | 2005-05-10 | Qlt, Inc. | Liposome compositions of porphyrin photosensitizers |
AR002009A1 (es) * | 1994-12-22 | 1998-01-07 | Astra Ab | Composicion farmaceutica, procedimiento para la manufactura de un polvo de proliposoma como el utilizado en dicha composicion, procedimiento para lamanufactura de dicha composicion, uso de dicha composicion farmaceutica en la manufactura de un medicamento y dispositivo inhalador de polvo seco. |
US5707608A (en) * | 1995-08-02 | 1998-01-13 | Qlt Phototherapeutics, Inc. | Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer |
JP2001511128A (ja) * | 1997-01-28 | 2001-08-07 | ファルマシア・アンド・アップジョン・カンパニー | 水不溶性ポルフィリンの脂質錯体の凍結乾燥物 |
WO1999013916A2 (fr) * | 1997-09-18 | 1999-03-25 | Nycomed Imaging As | Procedes et compositions pour l'imagerie medicale |
EP0911023A1 (fr) * | 1998-03-20 | 1999-04-28 | Mario Luca Russo | Compositions pharmaceutiques ou cosmétiques comprenant des substances photosensibles |
DE19852245A1 (de) * | 1998-11-12 | 2000-05-18 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Nanoemulsion |
PT1143992E (pt) * | 1999-01-27 | 2005-05-31 | Telik Inc | Composicoes farmaceuticas contendo analogos de glutationa |
US6608050B2 (en) | 1999-07-20 | 2003-08-19 | Pharmacia & Upjohn Company | Lyophilizate of lipid complex of water insoluble porphyrins |
AR032151A1 (es) | 2000-03-24 | 2003-10-29 | Novartis Ag | Uso de un farmaco anti-angiogenico en conjunto con un agente fotosensible para la preparacion de un medicamento para el tratamiento fotodinamico mejorado de la neovasculatura indeseada |
CA2408332C (fr) * | 2000-05-08 | 2011-02-15 | The University Of British Columbia | Supports pour formulations photosensibilisantes |
US6984395B2 (en) * | 2001-04-11 | 2006-01-10 | Qlt, Inc. | Drug delivery system for hydrophobic drugs |
DE60225844T2 (de) * | 2001-11-02 | 2009-04-09 | The Governors Of The University Of Alberta, Edmonton | Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator |
CA2513133A1 (fr) | 2003-01-16 | 2004-07-29 | Techno Mart Co., Ltd. | Derives de porphyrine |
US20040220167A1 (en) * | 2003-05-02 | 2004-11-04 | Nasrollah Samiy | Methods of treating neuralgic pain |
JP4741205B2 (ja) * | 2003-07-07 | 2011-08-03 | 真 湯浅 | 金属ポルフィリン錯体包埋リポソーム、その製造方法およびこれを利用する医薬 |
US20050048109A1 (en) * | 2003-08-26 | 2005-03-03 | Ceramoptec Industries, Inc. | Non-polar photosensitizer formulations for photodynamic therapy |
US8986731B2 (en) | 2003-08-26 | 2015-03-24 | Biolitec Pharma Marketing Ltd | Pegylated liposomal formulations of hydrophobic photosensitizers for photodynamic therapy |
US8709449B2 (en) * | 2004-02-12 | 2014-04-29 | Biolitec Pharma Marketing Ltd | Methods and compositions for improving photodynamic therapy through administration of lipids |
US20070031482A1 (en) * | 2005-08-02 | 2007-02-08 | Ceramoptec Industries, Ind. | PDT treatment method for cellulites and cosmetic use |
EP2007355A2 (fr) * | 2005-12-08 | 2008-12-31 | Wyeth a Corporation of the State of Delaware | Compositions liposomales |
US7465312B2 (en) | 2006-05-02 | 2008-12-16 | Green Medical, Inc. | Systems and methods for treating superficial venous malformations like spider veins |
US20070299431A1 (en) * | 2006-05-02 | 2007-12-27 | Green Medical, Inc. | Systems and methods for treating superficial venous malformations like spider veins |
ES2926857T3 (es) * | 2006-05-18 | 2022-10-31 | Biolitec Unternehmensbeteiligungs Ii Ag | Formulaciones en gel de fotosensibilizantes hidrófobos para aplicaciones en mucosas |
WO2008088037A1 (fr) * | 2007-01-18 | 2008-07-24 | National University Corporation Chiba University | Préparation médicinale à particules fines |
CN101861143B (zh) * | 2007-11-15 | 2015-09-09 | 拜莱泰克制药市场有限公司 | 用于炎性疾病的光动力治疗的聚乙二醇化脂质体制剂 |
WO2009067203A1 (fr) * | 2007-11-19 | 2009-05-28 | Ceramoptec Industries, Inc. | Composés pegylés pour la dégénérescence maculaire liée à l'âge |
US20100310660A1 (en) * | 2009-06-08 | 2010-12-09 | Taipei Medical University | Dry powder microparticles for pulmonary delivery |
US9211214B2 (en) | 2012-03-21 | 2015-12-15 | Valeant Pharmaceuticals International, Inc | Photodynamic therapy laser |
KR102630617B1 (ko) * | 2016-06-24 | 2024-01-29 | (주) 에이치엔에이파마켐 | 페오포르비드 a 및 폴리에틸렌글리콜의 지질 유도체의 결합체를 함유하는 항균 리포좀 조성물 |
WO2019173884A1 (fr) * | 2018-03-15 | 2019-09-19 | Bebeachibuli Romeo | Normalisateur biologique, procédé d'obtention de normalisateur biologique et produits obtenus avec ce normalisateur biologique |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
JPS60188329A (ja) * | 1984-03-07 | 1985-09-25 | Ajinomoto Co Inc | リポソ−ム封入物質移入促進剤 |
US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
US4776991A (en) * | 1986-08-29 | 1988-10-11 | The United States Of America As Represented By The Secretary Of The Navy | Scaled-up production of liposome-encapsulated hemoglobin |
US4920143A (en) * | 1987-04-23 | 1990-04-24 | University Of British Columbia | Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents |
JPH0780887B2 (ja) * | 1988-07-19 | 1995-08-30 | ザ ユニバーシティ オブ ブリティッシュ コロンビア | 波長特異的細胞毒性試薬 |
US4913907A (en) * | 1988-08-15 | 1990-04-03 | Cytopharm, Inc. | Porphycene anti-cancer agents and treatment methods |
US5010073A (en) * | 1989-10-05 | 1991-04-23 | The Rockefeller University | Use of liposomes as carriers for metalloporphyrins |
IL97681A (en) * | 1990-04-03 | 1996-01-31 | Ciba Geigy Ag | Liposome preparations containing synthetic lipids, given parenterally |
US5270053A (en) * | 1990-04-03 | 1993-12-14 | Ciba-Geigy Corp. | Parenterally administerable liposome formulation comprising synthetic lipid |
CA2047969A1 (fr) * | 1990-08-17 | 1992-02-18 | Thomas D. Madden | Ampoules contenant de la benzoporphyrine |
GB9111611D0 (en) * | 1991-05-30 | 1991-07-24 | Sandoz Ltd | Liposomes |
-
1993
- 1993-01-22 CA CA 2087902 patent/CA2087902C/fr not_active Expired - Lifetime
- 1993-02-02 MX MX9300560A patent/MX9300560A/es unknown
- 1993-02-04 KR KR1019930001488A patent/KR970007303B1/ko not_active IP Right Cessation
- 1993-02-05 DK DK93300863.3T patent/DK0569113T3/da active
- 1993-02-05 AT AT93300863T patent/ATE151984T1/de active
- 1993-02-05 ES ES93300863T patent/ES2100452T3/es not_active Expired - Lifetime
- 1993-02-05 DE DE69310014T patent/DE69310014T2/de not_active Expired - Lifetime
- 1993-02-05 JP JP5019105A patent/JP3020372B2/ja not_active Expired - Lifetime
- 1993-02-05 EP EP93300863A patent/EP0569113B1/fr not_active Expired - Lifetime
-
1995
- 1995-06-13 US US08/489,850 patent/US6074666A/en not_active Expired - Lifetime
-
1997
- 1997-06-26 GR GR970401554T patent/GR3023906T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0569113B1 (fr) | 1997-04-23 |
DE69310014D1 (de) | 1997-05-28 |
KR970007303B1 (ko) | 1997-05-07 |
EP0569113A1 (fr) | 1993-11-10 |
DE69310014T2 (de) | 1997-11-06 |
ES2100452T3 (es) | 1997-06-16 |
CA2087902A1 (fr) | 1993-08-06 |
JP3020372B2 (ja) | 2000-03-15 |
ATE151984T1 (de) | 1997-05-15 |
GR3023906T3 (en) | 1997-09-30 |
MX9300560A (es) | 1993-09-01 |
DK0569113T3 (da) | 1997-05-20 |
JPH06122628A (ja) | 1994-05-06 |
US6074666A (en) | 2000-06-13 |
Similar Documents
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CA2087902C (fr) | Compositions liposomiques renfermant des photosensibilisateurs a base de porphyrine | |
US6890555B1 (en) | Liposome compositions of porphyrin photosensitizers | |
US5707608A (en) | Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizer | |
RU2279872C2 (ru) | Система доставки лекарств для гидрофобных лекарственных препаратов | |
US7354599B2 (en) | Liposomal formulations of hydrophobic photosensitizer for photodynamic therapy | |
EP1030686B1 (fr) | Lyophilisat de complexe lipidique de porphyrines insolubles dans l'eau | |
JPH11509834A (ja) | ヒドロ−モノベンゾポルフィリン光増感剤を含有するリポソームの作成方法 | |
US6608050B2 (en) | Lyophilizate of lipid complex of water insoluble porphyrins | |
EP1465590B1 (fr) | Formulations contenant un lipide-polyethylene glycol | |
AU2007202603B2 (en) | Drug delivery system for hydrophobic drugs | |
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AU2002252874A1 (en) | Drug delivery system for hydrophobic drugs |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20130122 |