CA2086933A1 - Asphodelus composition for increasing white blood cell count - Google Patents
Asphodelus composition for increasing white blood cell countInfo
- Publication number
- CA2086933A1 CA2086933A1 CA002086933A CA2086933A CA2086933A1 CA 2086933 A1 CA2086933 A1 CA 2086933A1 CA 002086933 A CA002086933 A CA 002086933A CA 2086933 A CA2086933 A CA 2086933A CA 2086933 A1 CA2086933 A1 CA 2086933A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- extract
- asphodelus
- white blood
- grams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000000265 leukocyte Anatomy 0.000 title claims abstract description 42
- 239000000203 mixture Substances 0.000 title claims abstract description 38
- 241000244950 Asphodelus Species 0.000 title claims abstract description 12
- 238000004820 blood count Methods 0.000 title description 10
- 239000000284 extract Substances 0.000 claims abstract description 29
- 238000000034 method Methods 0.000 claims abstract description 24
- 241001465754 Metazoa Species 0.000 claims abstract description 12
- 241000282414 Homo sapiens Species 0.000 claims abstract description 8
- 230000007812 deficiency Effects 0.000 claims abstract description 5
- 239000003937 drug carrier Substances 0.000 claims abstract 3
- 239000008186 active pharmaceutical agent Substances 0.000 claims abstract 2
- 239000013543 active substance Substances 0.000 claims abstract 2
- 210000004698 lymphocyte Anatomy 0.000 claims description 29
- 241001067374 Asphodelus tenuifolius Species 0.000 claims description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 241000196324 Embryophyta Species 0.000 claims description 14
- 241000894007 species Species 0.000 claims description 7
- 239000002775 capsule Substances 0.000 claims description 5
- 239000006286 aqueous extract Substances 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims 1
- 239000006193 liquid solution Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 description 13
- 239000008280 blood Substances 0.000 description 13
- 239000000243 solution Substances 0.000 description 12
- 210000003743 erythrocyte Anatomy 0.000 description 10
- 238000005534 hematocrit Methods 0.000 description 10
- 102000001554 Hemoglobins Human genes 0.000 description 9
- 108010054147 Hemoglobins Proteins 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 9
- 210000001772 blood platelet Anatomy 0.000 description 8
- 241000241037 Asphodelus ramosus Species 0.000 description 7
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 210000000987 immune system Anatomy 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 208000030507 AIDS Diseases 0.000 description 5
- 241000700605 Viruses Species 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 5
- 238000004159 blood analysis Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000000605 extraction Methods 0.000 description 5
- 241001430294 unidentified retrovirus Species 0.000 description 5
- 208000032839 leukemia Diseases 0.000 description 4
- 210000001744 T-lymphocyte Anatomy 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 208000009746 Adult T-Cell Leukemia-Lymphoma Diseases 0.000 description 2
- 208000016683 Adult T-cell leukemia/lymphoma Diseases 0.000 description 2
- 241000390754 Asphodelus fistulosus Species 0.000 description 2
- 108010041397 CD4 Antigens Proteins 0.000 description 2
- 208000003322 Coinfection Diseases 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 241000701074 Human alphaherpesvirus 2 Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 201000006966 adult T-cell leukemia Diseases 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 238000009534 blood test Methods 0.000 description 2
- 230000007123 defense Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000004064 dysfunction Effects 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 231100000956 nontoxicity Toxicity 0.000 description 2
- 238000003305 oral gavage Methods 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 description 2
- 235000000458 Asphodeline lutea Nutrition 0.000 description 1
- 241000244954 Asphodelus aestivus Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 210000004366 CD4-positive T-lymphocyte Anatomy 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000031886 HIV Infections Diseases 0.000 description 1
- 208000037357 HIV infectious disease Diseases 0.000 description 1
- 102100034343 Integrase Human genes 0.000 description 1
- 241000726306 Irus Species 0.000 description 1
- 241000209510 Liliopsida Species 0.000 description 1
- 241001024304 Mino Species 0.000 description 1
- 229920000715 Mucilage Polymers 0.000 description 1
- 238000011887 Necropsy Methods 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 206010041509 Spherocytic anaemia Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 108020005202 Viral DNA Proteins 0.000 description 1
- 108020000999 Viral RNA Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 230000003466 anti-cipated effect Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000001851 biosynthetic effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 229940000406 drug candidate Drugs 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 239000003777 experimental drug Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000010413 gardening Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 244000144993 groups of animals Species 0.000 description 1
- 210000002443 helper t lymphocyte Anatomy 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 208000009601 hereditary spherocytosis Diseases 0.000 description 1
- 238000003898 horticulture Methods 0.000 description 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 239000012678 infectious agent Substances 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000000346 nonvolatile oil Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 235000017807 phytochemicals Nutrition 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 229930000223 plant secondary metabolite Natural products 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 229960002555 zidovudine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US555,583 | 1990-07-19 | ||
| US07/555,583 US5091181A (en) | 1990-07-19 | 1990-07-19 | Asphodelus composition for increasing white blood cell count |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2086933A1 true CA2086933A1 (en) | 1992-01-20 |
Family
ID=24217833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002086933A Abandoned CA2086933A1 (en) | 1990-07-19 | 1991-07-10 | Asphodelus composition for increasing white blood cell count |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5091181A (enExample) |
| EP (1) | EP0539516B1 (enExample) |
| JP (1) | JPH06504261A (enExample) |
| AT (1) | ATE164766T1 (enExample) |
| AU (1) | AU662108B2 (enExample) |
| CA (1) | CA2086933A1 (enExample) |
| DE (1) | DE69129232D1 (enExample) |
| OA (1) | OA09771A (enExample) |
| WO (1) | WO1992001461A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69420229T2 (de) * | 1993-11-19 | 2000-04-06 | Michio Tani | Pharmazeutische Zusammensetzung zur Behandlung von AIDS |
| US5955081A (en) | 1996-03-22 | 1999-09-21 | Moady Marzook | Antipsoriatic compositions, method of making, and method of using |
| ITUB20160655A1 (it) | 2016-02-11 | 2017-08-11 | Pietro Ceccobelli | Composizione di estratti di radice di asphodelo. |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US135083A (en) * | 1873-01-21 | Improvement in oyster-packing cans | ||
| US117338A (en) * | 1871-07-25 | Improvement in medical compounds for liver and other diseases | ||
| US65302A (en) * | 1867-05-28 | Improved medical compound | ||
| US40189A (en) * | 1863-10-06 | Improved composition for poultices | ||
| US132233A (en) * | 1872-10-15 | Improvement in medical compounds or antl-dyspeptic bitters | ||
| US43118A (en) * | 1864-06-14 | Improved medical preparation | ||
| JPS55108403A (en) * | 1979-02-13 | 1980-08-20 | Mitsubishi Chem Ind Ltd | Hypoglycemic |
| US4716120A (en) * | 1983-03-17 | 1987-12-29 | Minnesota Mining And Manufacturing Company | Stable allergenic extracts and methods |
-
1990
- 1990-07-19 US US07/555,583 patent/US5091181A/en not_active Expired - Lifetime
-
1991
- 1991-07-10 JP JP3514442A patent/JPH06504261A/ja active Pending
- 1991-07-10 CA CA002086933A patent/CA2086933A1/en not_active Abandoned
- 1991-07-10 EP EP91915070A patent/EP0539516B1/en not_active Expired - Lifetime
- 1991-07-10 DE DE69129232T patent/DE69129232D1/de not_active Expired - Lifetime
- 1991-07-10 AT AT91915070T patent/ATE164766T1/de not_active IP Right Cessation
- 1991-07-10 WO PCT/US1991/004857 patent/WO1992001461A1/en not_active Ceased
- 1991-07-10 AU AU84294/91A patent/AU662108B2/en not_active Ceased
-
1993
- 1993-01-14 OA OA60330A patent/OA09771A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06504261A (ja) | 1994-05-19 |
| AU662108B2 (en) | 1995-08-24 |
| AU8429491A (en) | 1992-02-18 |
| WO1992001461A1 (en) | 1992-02-06 |
| DE69129232D1 (de) | 1998-05-14 |
| US5091181A (en) | 1992-02-25 |
| OA09771A (en) | 1993-11-30 |
| EP0539516A1 (en) | 1993-05-05 |
| EP0539516B1 (en) | 1998-04-08 |
| ATE164766T1 (de) | 1998-04-15 |
| EP0539516A4 (enExample) | 1994-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |