CA2075970A1 - Heparin derivatives - Google Patents

Heparin derivatives

Info

Publication number
CA2075970A1
CA2075970A1 CA002075970A CA2075970A CA2075970A1 CA 2075970 A1 CA2075970 A1 CA 2075970A1 CA 002075970 A CA002075970 A CA 002075970A CA 2075970 A CA2075970 A CA 2075970A CA 2075970 A1 CA2075970 A1 CA 2075970A1
Authority
CA
Canada
Prior art keywords
heparin
process according
salts
molecular weight
heparin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002075970A
Other languages
English (en)
French (fr)
Inventor
Francesco Della Valle
Aurelio Romeo
Gunter Kirschner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2075970A1 publication Critical patent/CA2075970A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CA002075970A 1990-12-20 1991-12-20 Heparin derivatives Abandoned CA2075970A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT04175290A IT1243300B (it) 1990-12-20 1990-12-20 Derivati dell'eparina
IT41752A/90 1990-12-20

Publications (1)

Publication Number Publication Date
CA2075970A1 true CA2075970A1 (en) 1992-06-21

Family

ID=11253436

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002075970A Abandoned CA2075970A1 (en) 1990-12-20 1991-12-20 Heparin derivatives

Country Status (13)

Country Link
EP (1) EP0516792A1 (pt)
JP (1) JPH05504785A (pt)
KR (1) KR920703644A (pt)
CN (1) CN1062537A (pt)
AU (1) AU658594B2 (pt)
BR (1) BR9106234A (pt)
CA (1) CA2075970A1 (pt)
FI (1) FI923762A (pt)
HU (1) HUT62917A (pt)
IT (1) IT1243300B (pt)
NO (1) NO923240L (pt)
PT (1) PT99898A (pt)
WO (1) WO1992011294A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
FR2704861B1 (fr) * 1993-05-07 1995-07-28 Sanofi Elf Fractions d'héparine purifiées, procédé d'obtention et compositions pharmaceutiques les contenant.
ES2077533B1 (es) * 1994-02-28 1996-07-01 Bioiberica Procedimiento de obtencion de fracciones de oligosacaridos por despolimerizacion quimica de heparina.
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US5763427A (en) * 1995-03-31 1998-06-09 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US6001820A (en) * 1995-03-31 1999-12-14 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
AU1735097A (en) * 1996-03-15 1997-10-01 Takara Shuzo Co., Ltd. A product of heat treatment of uronic acid, food, drink or drug including the product
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
FR2763848B1 (fr) * 1997-05-28 2000-01-28 Rhone Poulenc Rorer Sa Utilisation des heparines de bas poids moleculaire pour la prevention et le traitement du trauma du systeme nerveux central
US20050232996A1 (en) * 2002-04-19 2005-10-20 Dirk Cremer Matrix comprising a bioactive component containing phospholipid
DE10217557A1 (de) * 2002-04-19 2003-11-06 Degussa Bioactives Gmbh Funktionsnahrungsmittel enthaltend eine Phospholipid-haltige stabile Matrix
CN100335506C (zh) * 2004-05-20 2007-09-05 汕头市金丰医疗器械科技有限公司 一种肝素化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2482603A1 (fr) * 1980-05-14 1981-11-20 Pharmindustrie Nouveaux esters d'heparine utilisables pour la preparation de medicaments, et procedes pour leur preparation
ES2071608T3 (es) * 1986-08-20 1995-07-01 Univ Miami Esteres de alcanoilo de heparina de bajo peso molecular.
SE8702254D0 (sv) * 1987-05-29 1987-05-29 Kabivitrum Ab Novel heparin derivatives

Also Published As

Publication number Publication date
HUT62917A (en) 1993-06-28
EP0516792A1 (en) 1992-12-09
NO923240L (no) 1992-10-19
JPH05504785A (ja) 1993-07-22
CN1062537A (zh) 1992-07-08
WO1992011294A1 (en) 1992-07-09
NO923240D0 (no) 1992-08-18
IT9041752A1 (it) 1992-06-21
PT99898A (pt) 1992-12-31
AU9096491A (en) 1992-07-22
FI923762A0 (fi) 1992-08-20
AU658594B2 (en) 1995-04-27
FI923762A (fi) 1992-08-20
BR9106234A (pt) 1993-03-30
KR920703644A (ko) 1992-12-18
IT1243300B (it) 1994-05-26
IT9041752A0 (it) 1990-12-20

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Legal Events

Date Code Title Description
FZDE Discontinued