CA2065287A1 - Isolats hvc nouveaux - Google Patents
Isolats hvc nouveauxInfo
- Publication number
- CA2065287A1 CA2065287A1 CA2065287A CA2065287A CA2065287A1 CA 2065287 A1 CA2065287 A1 CA 2065287A1 CA 2065287 A CA2065287 A CA 2065287A CA 2065287 A CA2065287 A CA 2065287A CA 2065287 A1 CA2065287 A1 CA 2065287A1
- Authority
- CA
- Canada
- Prior art keywords
- new
- hcv isolates
- new hcv
- isolates
- hcv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000711549 Hepacivirus C Species 0.000 abstract 3
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Laminated Bodies (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne deux nouveaux isolats du virus de l'hépatite C (HCV), à savoir J1 et J7. Ces nouveaux isolats comprennent des séquences de nucléotides et d'acides aminés qui sont distincts de l'isolat HCV prototype, HCV1. Ainsi, J1 et J7 constituent de nouveaux polynucléotides et polypeptides utilisés entre autre dans les diagnostics, la production de protéines de recombinaison et le développement de vaccins.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40804589A | 1989-09-15 | 1989-09-15 | |
US408,045 | 1989-09-15 | ||
US45614289A | 1989-12-21 | 1989-12-21 | |
US456,142 | 1989-12-21 | ||
PCT/US1990/005242 WO1991004262A1 (fr) | 1989-09-15 | 1990-09-14 | Nouveaux isolats du virus de l'hepatite c |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2065287A1 true CA2065287A1 (fr) | 1991-03-16 |
CA2065287C CA2065287C (fr) | 1999-12-21 |
Family
ID=27020120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002065287A Expired - Lifetime CA2065287C (fr) | 1989-09-15 | 1990-09-14 | Isolats hvc nouveaux |
Country Status (11)
Country | Link |
---|---|
EP (2) | EP0939128A3 (fr) |
JP (3) | JP3156200B2 (fr) |
AT (1) | ATE188998T1 (fr) |
CA (1) | CA2065287C (fr) |
DE (1) | DE69033425T3 (fr) |
DK (1) | DK0419182T4 (fr) |
ES (1) | ES2141081T5 (fr) |
GR (1) | GR3033100T3 (fr) |
IE (2) | IE903363A1 (fr) |
PT (1) | PT95329B (fr) |
WO (1) | WO1991004262A1 (fr) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7166287B1 (en) | 1989-12-18 | 2007-01-23 | Glaxo Wellcome Inc. | Viral agent |
NO905438L (no) | 1989-12-18 | 1991-06-19 | Wellcome Found | Virusmiddel. |
US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
AU7675491A (en) * | 1990-04-04 | 1991-10-30 | Chiron Corporation | Hepatitis c virus protease |
JP3050395B2 (ja) * | 1990-06-12 | 2000-06-12 | 国立感染症研究所長 | C型肝炎ウイルス抗原ポリペプチド、その産生方法および抗体の検出方法 |
US5747339A (en) | 1990-06-25 | 1998-05-05 | Research Foundation For Microbial Diseases Of Osaka | Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide |
DE69125066T2 (de) * | 1990-07-11 | 1997-09-25 | Shionogi Seiyaku K K Trading U | cDNS-Sequenz und Detektion des Hepatitis C-Virus |
WO1992001714A1 (fr) * | 1990-07-24 | 1992-02-06 | Yamanouchi Pharmaceutical Co., Ltd. | Antigene du virus de l'hepatite non a, non b |
ATE206717T1 (de) * | 1990-11-03 | 2001-10-15 | Dade Behring Marburg Gmbh | Hcv-spezifische peptide, mittel dazu und ihre verwendung |
EP0485209A1 (fr) * | 1990-11-08 | 1992-05-13 | Immuno Japan Inc. | Antigène relatif au virus de l'hépatite non-A non-B, systèmes de détection d'anticorps, polynucléotides et polypeptides |
KR920703640A (ko) * | 1990-11-29 | 1992-12-18 | 테루카츄 아리마 | 비a비b형 간염 바이러스 항원 단백질 |
US5574132A (en) * | 1991-04-05 | 1996-11-12 | Biochem Immunosystems Inc. | Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV) |
CA2065690A1 (fr) * | 1991-04-10 | 1992-10-11 | Hiroaki Okamoto | Antigenes lies a l'hepatite non-a, non-b, systemes de detection, polynucleotides et polypeptides |
CA2111108A1 (fr) | 1991-06-10 | 1992-12-23 | Joong Myung Cho | Diagnostic de l'hepatite c et vaccins |
RO117329B1 (ro) * | 1991-06-24 | 2002-01-30 | Chiron Corp Emeryville | Polipeptide care contin o secventa a virusului hepatitei c |
DK0529493T3 (da) * | 1991-08-27 | 1998-08-24 | Hoffmann La Roche | Fremgangsmåder og reagenser til hepatitis C-detektion |
CA2116764C (fr) * | 1991-09-13 | 1999-12-07 | Amy J. Weiner | Compositions de polypeptides du virus de l'hepatite c immunoreactives |
AU2679492A (en) * | 1991-09-16 | 1993-04-27 | Abbott Laboratories | Hepatitis c assay |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
US6620414B2 (en) | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
MA22842A1 (fr) * | 1992-03-27 | 1993-10-01 | Smithkline Beecham Biolog | Procede de preparation de compositions de vaccin. |
US6174868B1 (en) | 1992-09-10 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
US6433159B1 (en) | 1992-09-10 | 2002-08-13 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of Hepatitis C virus associated diseases |
US6995146B2 (en) | 1992-09-10 | 2006-02-07 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
US6391542B1 (en) | 1992-09-10 | 2002-05-21 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of Hepatitis C virus-associated diseases |
US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
BR9405334A (pt) | 1993-04-27 | 1999-05-25 | Innogenetics Nv | Novas sequências de genótipos de vírus da hepatite c e seu uso como agentes terapêuticos e diagnóstico |
DE69526973T3 (de) | 1994-10-21 | 2010-01-07 | Innogenetics N.V. | Sequenzen von hepatitis-c-virus genotype 7, und deren verwendung als vorbeugende, therapeutische und diagnostische mittel |
EP1178116A1 (fr) * | 2000-08-03 | 2002-02-06 | Hybrigenics S.A. | Acides nucléiques Sid et polypeptides sélectionnés à partir d'une souche pathogène du virus de l' hépatite ainsi que leurs applications |
ATE517184T1 (de) * | 2000-08-17 | 2011-08-15 | Tripep Ab | Hcv ns3/4a kodierende nukleinsäure |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
JP2002125688A (ja) * | 2000-10-30 | 2002-05-08 | Tosoh Corp | C型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法 |
DE10112748A1 (de) * | 2001-03-14 | 2002-09-19 | Transmit Technologietransfer | Erfindung betreffend HCV-Erkrankungen |
US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
AU2003258672B2 (en) * | 2002-09-13 | 2008-10-30 | Intercell Ag | Method for isolating hepatitis C virus peptides |
US8124747B2 (en) | 2003-08-29 | 2012-02-28 | Innogenetics | HCV clade and prototype sequences thereof |
US7473773B2 (en) | 2004-01-07 | 2009-01-06 | Third Wave Technologies, Inc. | Determination of hepatitis C virus genotype |
CN105697424B (zh) * | 2016-01-19 | 2019-01-08 | 江苏大学 | 一种泵站用防旋涡装置 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2480779B2 (fr) * | 1979-08-30 | 1986-07-18 | Anvar | Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur |
US4870026A (en) * | 1982-09-16 | 1989-09-26 | The General Hospital Corporation | Non-A, non-B. hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization |
US4673634A (en) * | 1985-03-08 | 1987-06-16 | The United States Of America As Represented By The Department Of Health And Human Services | Purified antigen from non-A, non-B hepatitis causing factor |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4868105A (en) | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
US5032511A (en) * | 1987-03-31 | 1991-07-16 | Mitsubishi Kasei Corporation | DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens |
JPH01124387A (ja) * | 1987-11-10 | 1989-05-17 | Mitsubishi Kasei Corp | 非a非b型肝炎特異抗原をコードするdnaを有する発現ベクター、形質転換体および該抗原の産生方法 |
JP2590885B2 (ja) * | 1987-03-31 | 1997-03-12 | 三菱化学株式会社 | Dna断片 |
CA1339351C (fr) | 1987-10-15 | 1997-08-26 | Michael S. Urdea | Multimeres d'acide nucleique et essais d'hybridation amplifiee d'acide nucleique |
CN1049686C (zh) * | 1987-11-18 | 2000-02-23 | 希龙股份有限公司 | 非a和非b肝炎病毒的诊断及疫苗 |
JP2500880Y2 (ja) * | 1988-05-02 | 1996-06-12 | カシオ計算機株式会社 | 液晶表示装置 |
KR0185373B1 (ko) * | 1989-03-17 | 1999-05-01 | 로버트 피. 블랙버언 | Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용 |
JPH0330676A (ja) * | 1989-06-28 | 1991-02-08 | Sanwa Kagaku Kenkyusho Co Ltd | 非a非b型肝炎ウイルスのdna、そのクローン及びこれらの調製法 |
EP0416725A3 (en) * | 1989-07-14 | 1991-03-20 | Chugai Seiyaku Kabushiki Kaisha | Blood-borne non-a, non-b hepatitis specific protein, dna encoding it, and process for its production |
-
1990
- 1990-09-14 JP JP51318890A patent/JP3156200B2/ja not_active Expired - Fee Related
- 1990-09-14 WO PCT/US1990/005242 patent/WO1991004262A1/fr active Application Filing
- 1990-09-14 CA CA002065287A patent/CA2065287C/fr not_active Expired - Lifetime
- 1990-09-17 AT AT90310149T patent/ATE188998T1/de not_active IP Right Cessation
- 1990-09-17 IE IE336390A patent/IE903363A1/en not_active IP Right Cessation
- 1990-09-17 DE DE69033425T patent/DE69033425T3/de not_active Expired - Lifetime
- 1990-09-17 ES ES90310149T patent/ES2141081T5/es not_active Expired - Lifetime
- 1990-09-17 DK DK90310149T patent/DK0419182T4/da active
- 1990-09-17 EP EP99101746A patent/EP0939128A3/fr not_active Withdrawn
- 1990-09-17 PT PT95329A patent/PT95329B/pt not_active IP Right Cessation
- 1990-09-17 EP EP90310149A patent/EP0419182B2/fr not_active Expired - Lifetime
-
1996
- 1996-10-24 JP JP8282753A patent/JPH09187285A/ja not_active Withdrawn
-
2000
- 2000-03-29 GR GR20000400789T patent/GR3033100T3/el unknown
-
2002
- 2002-02-19 IE IE20020123A patent/IE20020123A1/en not_active Application Discontinuation
-
2005
- 2005-01-26 JP JP2005018955A patent/JP2005143512A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
GR3033100T3 (en) | 2000-08-31 |
PT95329A (pt) | 1991-08-14 |
PT95329B (pt) | 1998-04-30 |
DE69033425T3 (de) | 2010-02-18 |
ES2141081T3 (es) | 2000-03-16 |
JPH05506773A (ja) | 1993-10-07 |
EP0419182A1 (fr) | 1991-03-27 |
EP0939128A2 (fr) | 1999-09-01 |
WO1991004262A1 (fr) | 1991-04-04 |
JP2005143512A (ja) | 2005-06-09 |
ES2141081T5 (es) | 2009-12-11 |
DE69033425T2 (de) | 2000-06-08 |
IE20020123A1 (en) | 2003-05-28 |
DE69033425D1 (de) | 2000-02-24 |
JPH09187285A (ja) | 1997-07-22 |
DK0419182T3 (da) | 2000-04-17 |
IE903363A1 (en) | 1991-04-10 |
JP3156200B2 (ja) | 2001-04-16 |
CA2065287C (fr) | 1999-12-21 |
DK0419182T4 (da) | 2009-11-23 |
EP0939128A3 (fr) | 2004-06-09 |
EP0419182B1 (fr) | 2000-01-19 |
EP0419182B2 (fr) | 2009-07-22 |
ATE188998T1 (de) | 2000-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |