CA2044550A1 - Methode de preparation de composes d'hydroxyvitamine d - Google Patents
Methode de preparation de composes d'hydroxyvitamine dInfo
- Publication number
- CA2044550A1 CA2044550A1 CA2044550A CA2044550A CA2044550A1 CA 2044550 A1 CA2044550 A1 CA 2044550A1 CA 2044550 A CA2044550 A CA 2044550A CA 2044550 A CA2044550 A CA 2044550A CA 2044550 A1 CA2044550 A1 CA 2044550A1
- Authority
- CA
- Canada
- Prior art keywords
- hydroxyvitamin
- compounds
- biological preparation
- compound
- microorganism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title 1
- -1 vitamin D compound Chemical class 0.000 abstract 3
- 229930003316 Vitamin D Natural products 0.000 abstract 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 235000019166 vitamin D Nutrition 0.000 abstract 2
- 239000011710 vitamin D Substances 0.000 abstract 2
- 229940046008 vitamin d Drugs 0.000 abstract 2
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000640 hydroxylating effect Effects 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15705490 | 1990-06-15 | ||
| JP02-157054 | 1990-06-15 | ||
| JP33428390A JP3201411B2 (ja) | 1990-06-15 | 1990-11-30 | ビタミンｄ類の生物学的製造方法 |
| JP02-334283 | 1990-11-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2044550A1 true CA2044550A1 (fr) | 1991-12-16 |
| CA2044550C CA2044550C (fr) | 2000-09-26 |
Family
ID=26484632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002044550A Expired - Lifetime CA2044550C (fr) | 1990-06-15 | 1991-06-13 | Methode de preparation de composes d'hydroxyvitamine d |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5474923A (fr) |
| EP (1) | EP0461921B1 (fr) |
| JP (1) | JP3201411B2 (fr) |
| KR (1) | KR100190412B1 (fr) |
| AT (1) | ATE127523T1 (fr) |
| CA (1) | CA2044550C (fr) |
| DE (1) | DE69112716T2 (fr) |
| ES (1) | ES2079573T3 (fr) |
| TW (1) | TW234147B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3201411B2 (ja) * | 1990-06-15 | 2001-08-20 | メルシャン株式会社 | ビタミンｄ類の生物学的製造方法 |
| WO1994000576A1 (fr) * | 1992-06-25 | 1994-01-06 | Taisho Pharmaceutical Co., Ltd. | Gene hydroxylase de vitamine d |
| DK0855445T3 (da) * | 1995-08-28 | 2003-06-30 | Mercian Corp | Fremgangsmåde til fremstilling af hydroxylerede cholesteroler ved biologisk omdannelse og dihydroxycholesteroler |
| AU3837100A (en) * | 1999-04-14 | 2000-11-14 | Chugai Seiyaku Kabushiki Kaisha | Vitamin d derivatives and process for producing the same |
| HUP0501186A2 (en) * | 2001-12-03 | 2006-05-29 | Novacea | Pharmaceutical compositions comprising active vitamin d compounds |
| US7148211B2 (en) * | 2002-09-18 | 2006-12-12 | Genzyme Corporation | Formulation for lipophilic agents |
| US20040058895A1 (en) * | 2002-09-18 | 2004-03-25 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
| CN101497595A (zh) * | 2004-01-29 | 2009-08-05 | 卫材R&D管理有限公司 | 大环内酯类化合物的稳定化方法 |
| EP2011781B1 (fr) | 2006-03-15 | 2014-03-05 | MicroBiopharm Japan Co., Ltd. | Procede de synthese d'un derive d'indene et intermediaire de synthese dudit derive |
| CN102482687B (zh) * | 2008-12-19 | 2014-08-27 | 一栋制药株式会社 | 骨化三醇或骨化二醇的生产促进用缓冲液组合物及利用其的骨化三醇或骨化二醇的制造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4307025A (en) * | 1981-02-17 | 1981-12-22 | Wisconsin Alumni Research Foundation | 1α, 25-dihydroxy-2β-fluorovitamin D3 |
| JPH0717686B2 (ja) * | 1986-08-08 | 1995-03-01 | メルシャン株式会社 | 部分メチル化シクロデキストリン及びその製造方法 |
| US4892821A (en) * | 1987-07-08 | 1990-01-09 | Taisho Pharmaceutical Co., Ltd. | Method for preparing vitamin D compounds |
| JP2663294B2 (ja) * | 1989-03-04 | 1997-10-15 | メルシャン株式会社 | ビタミンｄ類の製造方法 |
| JP3201411B2 (ja) * | 1990-06-15 | 2001-08-20 | メルシャン株式会社 | ビタミンｄ類の生物学的製造方法 |
-
1990
- 1990-11-30 JP JP33428390A patent/JP3201411B2/ja not_active Expired - Lifetime
-
1991
- 1991-06-07 US US07/711,988 patent/US5474923A/en not_active Expired - Lifetime
- 1991-06-11 TW TW080104561A patent/TW234147B/zh not_active IP Right Cessation
- 1991-06-13 CA CA002044550A patent/CA2044550C/fr not_active Expired - Lifetime
- 1991-06-14 KR KR1019910009817A patent/KR100190412B1/ko not_active IP Right Cessation
- 1991-06-14 DE DE69112716T patent/DE69112716T2/de not_active Expired - Fee Related
- 1991-06-14 ES ES91305415T patent/ES2079573T3/es not_active Expired - Lifetime
- 1991-06-14 EP EP91305415A patent/EP0461921B1/fr not_active Expired - Lifetime
- 1991-06-14 AT AT91305415T patent/ATE127523T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0461921A3 (en) | 1992-05-20 |
| DE69112716D1 (de) | 1995-10-12 |
| EP0461921B1 (fr) | 1995-09-06 |
| DE69112716T2 (de) | 1996-02-01 |
| US5474923A (en) | 1995-12-12 |
| ATE127523T1 (de) | 1995-09-15 |
| TW234147B (fr) | 1994-11-11 |
| CA2044550C (fr) | 2000-09-26 |
| JP3201411B2 (ja) | 2001-08-20 |
| KR920000934A (ko) | 1992-01-29 |
| ES2079573T3 (es) | 1996-01-16 |
| JPH04166090A (ja) | 1992-06-11 |
| KR100190412B1 (ko) | 1999-06-01 |
| EP0461921A2 (fr) | 1991-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed | ||
| MKEC | Expiry (correction) |
Effective date: 20121202 |