CA2033065A1 - Process for the production of 21-bromine-4-pregnene-3,20-dion derivatives - Google Patents

Process for the production of 21-bromine-4-pregnene-3,20-dion derivatives

Info

Publication number
CA2033065A1
CA2033065A1 CA002033065A CA2033065A CA2033065A1 CA 2033065 A1 CA2033065 A1 CA 2033065A1 CA 002033065 A CA002033065 A CA 002033065A CA 2033065 A CA2033065 A CA 2033065A CA 2033065 A1 CA2033065 A1 CA 2033065A1
Authority
CA
Canada
Prior art keywords
group
hydrogen atom
pregnene
stands
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002033065A
Other languages
English (en)
French (fr)
Inventor
Gerhard Hempel
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of CA2033065A1 publication Critical patent/CA2033065A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002033065A 1989-05-12 1990-05-07 Process for the production of 21-bromine-4-pregnene-3,20-dion derivatives Abandoned CA2033065A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3915951A DE3915951C1 (enExample) 1989-05-12 1989-05-12
DEP3915951.5 1989-05-12

Publications (1)

Publication Number Publication Date
CA2033065A1 true CA2033065A1 (en) 1990-11-13

Family

ID=6380760

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002033065A Abandoned CA2033065A1 (en) 1989-05-12 1990-05-07 Process for the production of 21-bromine-4-pregnene-3,20-dion derivatives

Country Status (10)

Country Link
US (1) US5332847A (enExample)
EP (1) EP0431151B1 (enExample)
JP (1) JP2842690B2 (enExample)
AT (1) ATE119912T1 (enExample)
CA (1) CA2033065A1 (enExample)
DD (1) DD297975A5 (enExample)
DE (2) DE3915951C1 (enExample)
DK (1) DK0431151T3 (enExample)
ES (1) ES2071832T3 (enExample)
WO (1) WO1990013558A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3557158A (en) * 1962-01-22 1971-01-19 Upjohn Co 6alpha-fluoro-16-methyl - 4 - pregnene 3,20-diones and intermediates produced in the synthesis thereof
US3646012A (en) * 1967-10-05 1972-02-29 Wyeth John & Brother Ltd Enamine salt protection of steroidal alpha beta-unsaturated ketones
DE2118218A1 (en) * 1971-04-10 1972-10-26 Schering Ag, 1000 Berlin Und 4619 Bergkamen Tetrahalo steroids - prepd by simultaneous addn of fluorine and chlorine on the delta 9(11)-double bond
YU54476A (en) * 1975-03-31 1982-05-31 Taisho Pharmaceutical Co Ltd Process for obtaining 17-ester 21-halo-pregnane
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3400188A1 (de) * 1984-01-02 1985-07-11 Schering AG, Berlin und Bergkamen, 1000 Berlin Neue 6(alpha),16(alpha)-dimethylkortikoide
DE3640709A1 (de) * 1986-11-28 1988-06-09 Schering Ag Verfahren zur herstellung von 6(alpha),9(alpha)-difluor-11ss,17(alpha)-dihydroxy-16(alpha)-methyl-4-pregnen-3,20-dion und dessen derivate

Also Published As

Publication number Publication date
JPH04500680A (ja) 1992-02-06
DE3915951C1 (enExample) 1990-09-13
DD297975A5 (de) 1992-01-30
EP0431151B1 (de) 1995-03-15
WO1990013558A1 (de) 1990-11-15
ATE119912T1 (de) 1995-04-15
ES2071832T3 (es) 1995-07-01
DE59008713D1 (de) 1995-04-20
DK0431151T3 (da) 1995-07-24
EP0431151A1 (de) 1991-06-12
US5332847A (en) 1994-07-26
JP2842690B2 (ja) 1999-01-06

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Legal Events

Date Code Title Description
FZDE Discontinued