CA2011587A1 - Compose induisant la secretion d'un facteur de croissance des nerfs - Google Patents
Compose induisant la secretion d'un facteur de croissance des nerfsInfo
- Publication number
- CA2011587A1 CA2011587A1 CA2011587A CA2011587A CA2011587A1 CA 2011587 A1 CA2011587 A1 CA 2011587A1 CA 2011587 A CA2011587 A CA 2011587A CA 2011587 A CA2011587 A CA 2011587A CA 2011587 A1 CA2011587 A1 CA 2011587A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- growth factor
- nerve growth
- factor secretion
- secretion inducing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000015336 Nerve Growth Factor Human genes 0.000 title abstract 2
- 108010025020 Nerve Growth Factor Proteins 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 229940053128 nerve growth factor Drugs 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP218255-1989 | 1989-08-24 | ||
JP1218255A JPH08768B2 (ja) | 1989-08-24 | 1989-08-24 | 神経成長因子分泌誘導剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2011587A1 true CA2011587A1 (fr) | 1991-02-24 |
CA2011587C CA2011587C (fr) | 1999-11-23 |
Family
ID=16717022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002011587A Expired - Fee Related CA2011587C (fr) | 1989-08-24 | 1990-03-06 | Compose induisant la secretion d'un facteur de croissance des nerfs |
Country Status (3)
Country | Link |
---|---|
US (1) | US5059627A (fr) |
JP (1) | JPH08768B2 (fr) |
CA (1) | CA2011587C (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19504003A1 (de) * | 1995-02-08 | 1996-08-14 | Martin Dr Kohlmeier | Verwendungen eines Vitamins der K-Gruppe |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5416242A (en) * | 1992-09-25 | 1995-05-16 | Nippon Hypox Laboratories Incorporated | Hydroquinone derivative |
US5281607B1 (en) * | 1992-10-08 | 1998-05-19 | Univ New York | Method of using alpha 2-antagonists for the treatment of neurodegenerative diseases |
ES2136167T3 (es) * | 1993-06-18 | 1999-11-16 | Takeda Chemical Industries Ltd | Composiciones de idebenona para tratar la enfermedad de alzheimer. |
DE19549262C2 (de) * | 1995-02-08 | 1997-10-09 | Martin Dr Kohlmeier | Präparat zur Abschätzung des Entstehungsrisikos eines beschleunigten Verlustes kognitiver Fähigkeiten |
EP0846109B1 (fr) * | 1995-08-21 | 2002-07-24 | Takeda Chemical Industries, Ltd. | Compose de quinone, sa production et son utilisation |
EP0788793A1 (fr) * | 1996-02-01 | 1997-08-13 | Takeda Chemical Industries, Ltd. | Idébenone pour le traitement de la démence |
DE69712888D1 (de) | 1996-07-11 | 2002-07-04 | Takeda Chemical Industries Ltd | ZUSAMMENSTELLUNGEN DIE beta-AMYLOID PROTEIN BEDINGTE ZYTOTOXIZITÄT VERHINDERN |
US5962535A (en) * | 1997-01-17 | 1999-10-05 | Takeda Chemical Industries, Ltd. | Composition for alzheimer's disease |
HUP0002482A3 (en) | 1997-02-03 | 2003-01-28 | Takeda Chemical Industries Ltd | Bicyclic quinone compounds, their production pharmaceutical compositions thereof and intermediates |
AU8562998A (en) * | 1997-08-12 | 1999-03-01 | Takeda Chemical Industries Ltd. | Idebenone-containing preparation for percutaneous administration |
DE19932197A1 (de) | 1999-07-09 | 2001-01-18 | Neudecker Birgit | Topisch anzuwendendes Mittel mit schützender und regenerativer Wirkung |
AU2001228825A1 (en) * | 2000-01-27 | 2001-08-07 | Takara Bio Inc. | Remedies |
EP1293200A4 (fr) * | 2000-02-08 | 2004-10-13 | Hisamitsu Pharmaceutical Co | Potentialisateurs du facteur de croissance neuronal |
TWI329513B (en) * | 2001-10-12 | 2010-09-01 | Kaneka Corp | Use of reduced coenzyme q for lessening oxidative stress |
JP2003226639A (ja) * | 2002-01-31 | 2003-08-12 | Hisamitsu Pharmaceut Co Inc | 神経成長因子活性増強剤としてのビタミンk類を含む医薬組成物およびその使用 |
FR2860233B1 (fr) * | 2003-09-26 | 2007-10-19 | Univ Pasteur | Composes promoteurs de la differenciation des precurseurs d'oligodendrocytes et modulateurs de l'activation microgliale, compositions et utilisations. |
US20050152857A1 (en) * | 2004-01-08 | 2005-07-14 | Pcr Technology Holdings, Lc | Method and preparation for reducing sunburn cell formation in skin |
US20050175559A1 (en) * | 2004-02-10 | 2005-08-11 | Pcr Technology Holdings, Lc | Method and preparation for reducing skin hyperpigmentation |
US20050197407A1 (en) * | 2004-02-13 | 2005-09-08 | Pcr Technology Holdings, Lc | Method and preparation for reducing irritation and/or inflammatory reaction in human skin |
JP5150807B2 (ja) * | 2005-02-28 | 2013-02-27 | 株式会社明治 | ハイドロキノン長鎖誘導体及び/又はフェノキシ長鎖誘導体及びこれらを含有する医薬 |
ES2714900T3 (es) | 2005-06-01 | 2019-05-30 | Bioelectron Tech Corp | Productos terapéuticos redox activos para el tratamiento de enfermedades mitocondriales y otras afecciones y modulación de biomarcadores energéticos |
ES2823728T3 (es) * | 2005-09-15 | 2021-05-10 | Ptc Therapeutics Inc | Variantes de cola de agentes terapéuticos con actividad redox para el tratamiento de enfermedades mitocondriales y otras afecciones y la modulación de biomarcadores de energía |
AR053665A1 (es) * | 2006-01-23 | 2007-05-16 | Creactivar S A | Uso de la mimosina o un derivado de la misma, en el tratamiento de las manifestaciones cutaneas de la psoriasis y de los desordenes cutaneos relacionados con esta y una composicion cosmetica o farmaceutica que la comprende |
WO2007100652A2 (fr) | 2006-02-22 | 2007-09-07 | Edison Pharmaceuticals, Inc. | Variants à chaînes latérales d'agents thérapeutiques ayant une activité oxydoréductrice pour le traitement de maladies mitochondriales et d'autres conditions et pour la modulation de biomarqueurs énergétiques |
JP4845038B2 (ja) * | 2007-03-01 | 2011-12-28 | 敏雄 鈴木 | 鋼材コイル転倒防止具及び転倒防止方法 |
LT3827815T (lt) | 2008-09-10 | 2023-10-10 | Ptc Therapeutics, Inc. | Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais |
CA2908929C (fr) | 2012-07-12 | 2021-01-26 | Concert Pharmaceuticals, Inc. | Idebenone deuteree |
CA3008849A1 (fr) | 2015-12-17 | 2017-06-22 | Bioelectron Technology Corporation | Derives fluoroalkyle, fluoroalcoxy, phenoxy, heteroaryloxy, alcoxy, et amine 1,4-benzoquinone pour le traitement de troubles du stress oxydatif |
EP4257190A3 (fr) | 2018-10-17 | 2024-01-03 | PTC Therapeutics, Inc. | 2,3,5-triméthyl-6-nonylcyclohexa-2,5-diène-1,4-dione pour la suppression et le traitement des alpha-synucléinopathies, des tauopathies et d'autres troubles |
IL310011A (en) | 2021-07-08 | 2024-03-01 | Ptc Therapeutics Inc | Pharmaceutical compositions containing 2,3,5-trimethyl-6-nonylcyclohexa-2,5-diene-1,4-dione |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5697223A (en) * | 1979-12-30 | 1981-08-05 | Takeda Chem Ind Ltd | Tissue metabolism activator |
US4393075A (en) * | 1980-04-14 | 1983-07-12 | Takeda Chemical Industries, Ltd. | Quinone compounds and their use in suppressing the production of SRS-A in mammals |
MX9203040A (es) * | 1984-08-01 | 1992-07-31 | Takeda Chemical Industries Ltd | Derivados de quinona y composicion farmaceutica que los contiene. |
IL81264A (en) * | 1986-01-30 | 1990-11-05 | Takeda Chemical Industries Ltd | Quinone derivatives,their production and pharmaceutical compositions containing them |
US4851431A (en) * | 1986-11-26 | 1989-07-25 | Bar Ilan University | Physiologically active and nutritional composition |
JPH0813741B2 (ja) * | 1987-08-10 | 1996-02-14 | 協和醗酵工業株式会社 | 抗痴呆剤 |
-
1989
- 1989-08-24 JP JP1218255A patent/JPH08768B2/ja not_active Expired - Lifetime
-
1990
- 1990-03-02 US US07/487,249 patent/US5059627A/en not_active Expired - Lifetime
- 1990-03-06 CA CA002011587A patent/CA2011587C/fr not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19504003A1 (de) * | 1995-02-08 | 1996-08-14 | Martin Dr Kohlmeier | Verwendungen eines Vitamins der K-Gruppe |
Also Published As
Publication number | Publication date |
---|---|
US5059627A (en) | 1991-10-22 |
CA2011587C (fr) | 1999-11-23 |
JPH08768B2 (ja) | 1996-01-10 |
JPH0381218A (ja) | 1991-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |