CA2005358A1 - Analogues de la somatotrophine - Google Patents
Analogues de la somatotrophineInfo
- Publication number
- CA2005358A1 CA2005358A1 CA002005358A CA2005358A CA2005358A1 CA 2005358 A1 CA2005358 A1 CA 2005358A1 CA 002005358 A CA002005358 A CA 002005358A CA 2005358 A CA2005358 A CA 2005358A CA 2005358 A1 CA2005358 A1 CA 2005358A1
- Authority
- CA
- Canada
- Prior art keywords
- rbst
- somatotropin
- animal
- serine
- asparagine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Landscapes
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| US29910789A | 1989-01-19 | 1989-01-19 | |
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| CA2005358A1 true CA2005358A1 (fr) | 1990-07-19 |
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| CA002005358A Abandoned CA2005358A1 (fr) | 1989-01-19 | 1989-12-13 | Analogues de la somatotrophine |
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| DK (1) | DK136991D0 (fr) |
| WO (1) | WO1990008164A1 (fr) |
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| DE68929273T2 (de) * | 1988-08-24 | 2001-07-05 | American Cyanamid Co | Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung |
| ZA936811B (en) * | 1992-10-28 | 1995-03-15 | Upjohn Co | Somatotropin modifications |
| US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7795210B2 (en) | 2001-10-10 | 2010-09-14 | Novo Nordisk A/S | Protein remodeling methods and proteins/peptides produced by the methods |
| US8008252B2 (en) | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
| US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| ES2420581T3 (es) | 2003-03-14 | 2013-08-26 | Biogenerix Gmbh | Polímeros solubles en agua ramificados y sus conjugados |
| MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
| ATE540055T1 (de) * | 2003-05-09 | 2012-01-15 | Biogenerix Ag | Zusammensetzungen und verfahren zur herstellung von glykosylierungsmutanten des menschlichen wachstumshormons |
| WO2005012484A2 (fr) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Conjugues anticorps-toxines |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| US7956032B2 (en) | 2003-12-03 | 2011-06-07 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| WO2005070138A2 (fr) | 2004-01-08 | 2005-08-04 | Neose Technologies, Inc. | Glycosylation de peptides liee a o |
| US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
| EP1799249A2 (fr) | 2004-09-10 | 2007-06-27 | Neose Technologies, Inc. | Interferon alpha glycopegyle |
| EP1814573B1 (fr) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodelage et glycopegylation du facteur de croissance des fibroblastes (fgf) |
| JP4951527B2 (ja) | 2005-01-10 | 2012-06-13 | バイオジェネリックス アーゲー | 糖ｐｅｇ化顆粒球コロニー刺激因子 |
| EP2386571B1 (fr) | 2005-04-08 | 2016-06-01 | ratiopharm GmbH | Compositions et méthodes utilisées pour la préparation de mutants par glycosylation de l'hormone de croissance humaine résistant à la protéase |
| WO2006127910A2 (fr) | 2005-05-25 | 2006-11-30 | Neose Technologies, Inc. | Formulations d'erythropoietine glycopegylees |
| US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
| EP2049144B8 (fr) | 2006-07-21 | 2015-02-18 | ratiopharm GmbH | Glycosylation de peptides par l'intermédiaire de séquences de glycosylation à liaison o |
| JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー／エス | ポリペプチドコンジュゲートの精製方法 |
| EP2144923B1 (fr) | 2007-04-03 | 2013-02-13 | BioGeneriX AG | Méthodes de traitement à l'aide d'un facteur g-csf glycopégylé |
| WO2008154639A2 (fr) | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Procédé amélioré pour la production de sucres de nucléotide |
| US8207112B2 (en) | 2007-08-29 | 2012-06-26 | Biogenerix Ag | Liquid formulation of G-CSF conjugate |
| CN101965200B (zh) | 2008-02-27 | 2013-06-19 | 诺沃-诺迪斯克有限公司 | 缀合的因子ⅷ分子 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ201918A (en) * | 1981-09-18 | 1987-04-30 | Genentech Inc | N-terminal methionyl analogues of bovine growth hormone |
| EP0085036A1 (fr) * | 1982-01-18 | 1983-08-03 | Monsanto Company | Méthode pour une production améliorée de lait de bovins |
| US4446235A (en) * | 1982-03-22 | 1984-05-01 | Genentech, Inc. | Method for cloning human growth hormone varient genes |
| ATE57937T1 (de) * | 1985-09-18 | 1990-11-15 | Upjohn Co | Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung. |
| US5104806A (en) * | 1987-03-12 | 1992-04-14 | Amgen, Inc. | Porcine growth hormone analogs encoding dna |
-
1989
- 1989-12-11 WO PCT/US1989/005447 patent/WO1990008164A1/fr not_active Application Discontinuation
- 1989-12-11 KR KR1019900702070A patent/KR910700264A/ko not_active Application Discontinuation
- 1989-12-11 JP JP2502084A patent/JPH04502762A/ja active Pending
- 1989-12-11 AU AU49427/90A patent/AU634517B2/en not_active Ceased
- 1989-12-11 EP EP90901997A patent/EP0454730A1/fr not_active Withdrawn
- 1989-12-13 CA CA002005358A patent/CA2005358A1/fr not_active Abandoned
-
1991
- 1991-07-17 DK DK911369A patent/DK136991D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU4942790A (en) | 1990-08-13 |
| AU634517B2 (en) | 1993-02-25 |
| JPH04502762A (ja) | 1992-05-21 |
| EP0454730A1 (fr) | 1991-11-06 |
| DK136991A (da) | 1991-07-17 |
| WO1990008164A1 (fr) | 1990-07-26 |
| DK136991D0 (da) | 1991-07-17 |
| KR910700264A (ko) | 1991-03-14 |
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| EEER | Examination request | ||
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