ATE57937T1 - Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung. - Google Patents

Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung.

Info

Publication number
ATE57937T1
ATE57937T1 AT86905640T AT86905640T ATE57937T1 AT E57937 T1 ATE57937 T1 AT E57937T1 AT 86905640 T AT86905640 T AT 86905640T AT 86905640 T AT86905640 T AT 86905640T AT E57937 T1 ATE57937 T1 AT E57937T1
Authority
AT
Austria
Prior art keywords
species
bst
bioeffects
enhanced
deamidation
Prior art date
Application number
AT86905640T
Other languages
English (en)
Inventor
Gary C Harbour
John G Hoogerheide
Robert L Garlick
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE57937T1 publication Critical patent/ATE57937T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT86905640T 1985-09-18 1986-09-15 Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung. ATE57937T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77715485A 1985-09-18 1985-09-18
PCT/US1986/001860 WO1987001708A2 (en) 1985-09-18 1986-09-15 Enhanced bioactivity of mammalian somatotropin through selective deamidation
EP86905640A EP0236452B1 (de) 1985-09-18 1986-09-15 Erhöhte biowirkung von säugetier-somatotropin durch selektive deamidierung

Publications (1)

Publication Number Publication Date
ATE57937T1 true ATE57937T1 (de) 1990-11-15

Family

ID=25109437

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86905640T ATE57937T1 (de) 1985-09-18 1986-09-15 Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung.

Country Status (5)

Country Link
EP (1) EP0236452B1 (de)
JP (1) JPS63500941A (de)
AT (1) ATE57937T1 (de)
DE (1) DE3675382D1 (de)
WO (1) WO1987001708A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631227A (en) * 1985-09-18 1997-05-20 The Upjohn Company Somatotropin analogs
CA1338720C (en) * 1988-03-15 1996-11-12 Gerald Wayne Becker Derivative of human growth hormone
US5089473A (en) * 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
JPH04502762A (ja) * 1989-01-19 1992-05-21 ジ・アップジョン・カンパニー ソマトトロピン・アナログ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty

Also Published As

Publication number Publication date
WO1987001708A3 (en) 1987-08-13
DE3675382D1 (de) 1990-12-06
EP0236452B1 (de) 1990-10-31
WO1987001708A2 (en) 1987-03-26
EP0236452A1 (de) 1987-09-16
JPS63500941A (ja) 1988-04-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee