DE3675382D1 - Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung. - Google Patents

Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung.

Info

Publication number
DE3675382D1
DE3675382D1 DE8686905640T DE3675382T DE3675382D1 DE 3675382 D1 DE3675382 D1 DE 3675382D1 DE 8686905640 T DE8686905640 T DE 8686905640T DE 3675382 T DE3675382 T DE 3675382T DE 3675382 D1 DE3675382 D1 DE 3675382D1
Authority
DE
Germany
Prior art keywords
species
bst
somatotropine
mammal
biological effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686905640T
Other languages
English (en)
Inventor
C Harbour
G Hoogerheide
L Garlick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of DE3675382D1 publication Critical patent/DE3675382D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8686905640T 1985-09-18 1986-09-15 Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung. Expired - Fee Related DE3675382D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77715485A 1985-09-18 1985-09-18
PCT/US1986/001860 WO1987001708A2 (en) 1985-09-18 1986-09-15 Enhanced bioactivity of mammalian somatotropin through selective deamidation

Publications (1)

Publication Number Publication Date
DE3675382D1 true DE3675382D1 (de) 1990-12-06

Family

ID=25109437

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686905640T Expired - Fee Related DE3675382D1 (de) 1985-09-18 1986-09-15 Erhoehte biowirkung von saeugetier-somatotropin durch selektive deamidierung.

Country Status (5)

Country Link
EP (1) EP0236452B1 (de)
JP (1) JPS63500941A (de)
AT (1) ATE57937T1 (de)
DE (1) DE3675382D1 (de)
WO (1) WO1987001708A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631227A (en) * 1985-09-18 1997-05-20 The Upjohn Company Somatotropin analogs
ZA891863B (en) * 1988-03-15 1990-11-28 Lilly Co Eli Novel derivative of human growth hormone
US5089473A (en) * 1988-08-29 1992-02-18 Monsanto Company Somatotropin variants and their use
JPH04502762A (ja) * 1989-01-19 1992-05-21 ジ・アップジョン・カンパニー ソマトトロピン・アナログ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
BG49718A3 (en) * 1983-07-15 1992-01-15 Bio- Technology General Corp Method for preparing of polypeptid with superoxiddismutasne activitty

Also Published As

Publication number Publication date
ATE57937T1 (de) 1990-11-15
WO1987001708A2 (en) 1987-03-26
JPS63500941A (ja) 1988-04-07
EP0236452A1 (de) 1987-09-16
EP0236452B1 (de) 1990-10-31
WO1987001708A3 (en) 1987-08-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US

8339 Ceased/non-payment of the annual fee