CA2005122A1 - Control of microbial growth with nisin/lysozyme formulations - Google Patents
Control of microbial growth with nisin/lysozyme formulationsInfo
- Publication number
- CA2005122A1 CA2005122A1 CA002005122A CA2005122A CA2005122A1 CA 2005122 A1 CA2005122 A1 CA 2005122A1 CA 002005122 A CA002005122 A CA 002005122A CA 2005122 A CA2005122 A CA 2005122A CA 2005122 A1 CA2005122 A1 CA 2005122A1
- Authority
- CA
- Canada
- Prior art keywords
- nisin
- lysozyme
- growth
- microbial growth
- environment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 title claims abstract description 97
- 108010053775 Nisin Proteins 0.000 title claims abstract description 97
- 239000004309 nisin Substances 0.000 title claims abstract description 97
- 235000010297 nisin Nutrition 0.000 title claims abstract description 97
- 235000010335 lysozyme Nutrition 0.000 title claims abstract description 79
- 239000004325 lysozyme Substances 0.000 title claims abstract description 79
- 229960000274 lysozyme Drugs 0.000 title claims abstract description 79
- 108010014251 Muramidase Proteins 0.000 title claims abstract description 78
- 102000016943 Muramidase Human genes 0.000 title claims abstract description 78
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 title claims abstract description 78
- 230000012010 growth Effects 0.000 title claims abstract description 30
- 230000000813 microbial effect Effects 0.000 title claims abstract description 14
- 239000000203 mixture Substances 0.000 title description 6
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract description 18
- 230000002401 inhibitory effect Effects 0.000 claims abstract description 5
- 241000186779 Listeria monocytogenes Species 0.000 claims description 21
- 241000894006 Bacteria Species 0.000 claims description 14
- 244000005700 microbiome Species 0.000 claims description 11
- 235000013305 food Nutrition 0.000 claims description 8
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- 235000014897 Streptococcus lactis Nutrition 0.000 claims description 4
- 241000192125 Firmicutes Species 0.000 claims description 3
- 229940000425 combination drug Drugs 0.000 claims description 3
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- 230000004151 fermentation Effects 0.000 claims description 3
- 241000283690 Bos taurus Species 0.000 claims 1
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- 230000000694 effects Effects 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 5
- 102000002322 Egg Proteins Human genes 0.000 description 5
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- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
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- GDSYPXWUHMRTHT-UHFFFAOYSA-N Epidermin Natural products N#CCC(C)(C)OC1OC(CO)C(O)C(O)C1O GDSYPXWUHMRTHT-UHFFFAOYSA-N 0.000 description 2
- 101001018100 Homo sapiens Lysozyme C Proteins 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 2
- 241000186781 Listeria Species 0.000 description 2
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 2
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- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
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- 210000002421 cell wall Anatomy 0.000 description 2
- RKLXDNHNLPUQRB-TVJUEJKUSA-N chembl564271 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]2C(C)SC[C@H](N[C@@H](CC(N)=O)C(=O)NC(=O)[C@@H](NC2=O)CSC1C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(=C)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H]1NC(=O)C(=C\C)/NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2NC(=O)CNC(=O)[C@@H]3CCCN3C(=O)[C@@H](NC(=O)[C@H]3N[C@@H](CC(C)C)C(=O)NC(=O)C(=C)NC(=O)CC[C@H](NC(=O)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=4C5=CC=CC=C5NC=4)CSC3)C(O)=O)C(C)SC2)C(C)C)C(C)SC1)C1=CC=CC=C1 RKLXDNHNLPUQRB-TVJUEJKUSA-N 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
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- 108010064962 epidermin Proteins 0.000 description 2
- CXTXHTVXPMOOSW-JUEJINBGSA-N epidermin Chemical compound C([C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSC[C@H](C(N[C@@H](CCCCN)C(=O)N1)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)CC)C(=O)N[C@H]1C(N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](CS[C@H]1C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N\C(=C/C)C(=O)NCC(=O)N[C@H]1C(N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]2C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@H](C(N\C=C/SC2)=O)CSC1)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 CXTXHTVXPMOOSW-JUEJINBGSA-N 0.000 description 2
- 235000021107 fermented food Nutrition 0.000 description 2
- 238000009920 food preservation Methods 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000010534 mechanism of action Effects 0.000 description 2
- 229950006780 n-acetylglucosamine Drugs 0.000 description 2
- 235000002949 phytic acid Nutrition 0.000 description 2
- 229940068041 phytic acid Drugs 0.000 description 2
- 239000000467 phytic acid Substances 0.000 description 2
- 235000020991 processed meat Nutrition 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 235000014102 seafood Nutrition 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 108010082567 subtilin Proteins 0.000 description 2
- 102000044503 Antimicrobial Peptides Human genes 0.000 description 1
- 108700042778 Antimicrobial Peptides Proteins 0.000 description 1
- -1 B-methyllanthionine Chemical class 0.000 description 1
- 241000304886 Bacilli Species 0.000 description 1
- 244000063299 Bacillus subtilis Species 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- 241001112696 Clostridia Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 241000193155 Clostridium botulinum Species 0.000 description 1
- 241000193171 Clostridium butyricum Species 0.000 description 1
- 241000193452 Clostridium tyrobutyricum Species 0.000 description 1
- 101100129080 Crassostrea virginica lysoz1 gene Proteins 0.000 description 1
- UQBOJOOOTLPNST-UHFFFAOYSA-N Dehydroalanine Chemical compound NC(=C)C(O)=O UQBOJOOOTLPNST-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 241000701533 Escherichia virus T4 Species 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- DWPCPZJAHOETAG-IMJSIDKUSA-N L-lanthionine Chemical compound OC(=O)[C@@H](N)CSC[C@H](N)C(O)=O DWPCPZJAHOETAG-IMJSIDKUSA-N 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 206010024641 Listeriosis Diseases 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 201000009906 Meningitis Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 108020004511 Recombinant DNA Proteins 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-M Thiocyanate anion Chemical compound [S-]C#N ZMZDMBWJUHKJPS-UHFFFAOYSA-M 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
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- 235000010233 benzoic acid Nutrition 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
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- 210000004556 brain Anatomy 0.000 description 1
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- 238000007385 chemical modification Methods 0.000 description 1
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- 150000002148 esters Chemical class 0.000 description 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
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- 238000002474 experimental method Methods 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
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- 239000005452 food preservative Substances 0.000 description 1
- 244000078673 foodborn pathogen Species 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N hydrogen thiocyanate Natural products SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
- DWPCPZJAHOETAG-UHFFFAOYSA-N meso-lanthionine Natural products OC(=O)C(N)CSCC(N)C(O)=O DWPCPZJAHOETAG-UHFFFAOYSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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- 235000016709 nutrition Nutrition 0.000 description 1
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- 150000007524 organic acids Chemical class 0.000 description 1
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- 230000005789 organism growth Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
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- 238000012545 processing Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
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- 235000014214 soft drink Nutrition 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
- A23C19/063—Addition of, or treatment with, enzymes or cell-free extracts of microorganisms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/742—Organic compounds containing oxygen
- A23B2/75—Organic compounds containing oxygen with doubly-bound oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/762—Organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23B2/00—Preservation of foods or foodstuffs, in general
- A23B2/70—Preservation of foods or foodstuffs, in general by treatment with chemicals
- A23B2/725—Preservation of foods or foodstuffs, in general by treatment with chemicals in the form of liquids or solids
- A23B2/729—Organic compounds; Microorganisms; Enzymes
- A23B2/783—Microorganisms; Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Agronomy & Crop Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Dairy Products (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28771988A | 1988-12-21 | 1988-12-21 | |
| US287,719 | 1988-12-21 | ||
| US43467189A | 1989-11-16 | 1989-11-16 | |
| US434,671 | 1989-11-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2005122A1 true CA2005122A1 (en) | 1991-05-16 |
Family
ID=26964619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002005122A Abandoned CA2005122A1 (en) | 1988-12-21 | 1989-12-11 | Control of microbial growth with nisin/lysozyme formulations |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0374823B1 (OSRAM) |
| JP (1) | JPH02283269A (OSRAM) |
| AR (1) | AR243743A1 (OSRAM) |
| AU (1) | AU620481B2 (OSRAM) |
| CA (1) | CA2005122A1 (OSRAM) |
| DE (1) | DE68911279T2 (OSRAM) |
| DK (1) | DK649689A (OSRAM) |
| ES (1) | ES2047100T3 (OSRAM) |
| MX (1) | MX170613B (OSRAM) |
| NO (1) | NO174793B (OSRAM) |
| NZ (1) | NZ231764A (OSRAM) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68913189T2 (de) * | 1988-06-22 | 1994-05-19 | Applied Microbiology, Inc., Brooklyn, N.Y. | Nisin-zusammensetzungen zur anwendung als erhöhte breit-spektrum-bakterizide. |
| GR1001135B (el) * | 1989-09-05 | 1993-04-28 | Dusar Heinz | Διαταξις δια την συγκρατηση μιας κουρτινας (παραπετασματος) ντους. |
| PH30997A (en) * | 1990-03-12 | 1997-12-23 | Ciba Geigy | Antipathologenically effective compositions comprising lytic peptides and hydrolytic enzymes. |
| NO911341L (no) * | 1990-04-20 | 1991-10-21 | Haarmann & Reimer Corp | Fremgangsmaate for aa drepe gram-negative bakterier. |
| EP0466244A1 (en) * | 1990-07-13 | 1992-01-15 | Unilever N.V. | Compositions having antibacterial properties and use of such compositions in suppressing growth of microorganisms, eg. Listeria bacteria |
| WO1993004588A1 (en) * | 1991-09-05 | 1993-03-18 | Haarmann & Reimer Corporation | Composition and method of attenuation of ionic strength inhibition of lantibiotics |
| JP3040282B2 (ja) * | 1993-07-30 | 2000-05-15 | アサマ化成株式会社 | 食品用保存剤 |
| JP3042573B2 (ja) * | 1993-07-30 | 2000-05-15 | アサマ化成株式会社 | 食品用保存剤 |
| JP3040294B2 (ja) * | 1993-10-27 | 2000-05-15 | アサマ化成株式会社 | 食品用保存剤 |
| JP3040293B2 (ja) * | 1993-10-27 | 2000-05-15 | 多聞酒造株式会社 | 食品用保存剤 |
| JP3040295B2 (ja) * | 1993-10-27 | 2000-05-15 | アサマ化成株式会社 | 食品用保存剤 |
| ZA964329B (en) * | 1995-06-07 | 1996-08-26 | Applied Microbiology Inc | Method of using lantibiotics in a bactericidal role to effect destruction of listeria monocytogenes in processed crustacean species |
| WO1997032480A1 (en) * | 1996-03-06 | 1997-09-12 | Novo Nordisk A/S | A method of killing or inhibiting microbial cells |
| CA2658440C (en) | 2008-04-04 | 2016-08-23 | Kraft Foods Global Brands Llc | Dairy composition with probiotics and anti-microbial system |
| WO2014209912A1 (en) | 2013-06-27 | 2014-12-31 | Starbucks Corporation D/B/A Starbucks Coffee Company | Biopreservation methods for beverages and other foods |
| US12123144B2 (en) * | 2020-08-21 | 2024-10-22 | Danimer Ipco, Llc | Antimicrobial biodegradable compositions for food contact articles |
| KR102297406B1 (ko) * | 2021-01-22 | 2021-09-07 | 주식회사 커스토젠 | 피부상재 미생물 조절용 조성물 |
| CN113598198A (zh) * | 2021-08-05 | 2021-11-05 | 天津科技大学 | 一种农作物细菌性软腐病抗病蛋白糖联体的制备方法和产品及其应用 |
| CN115990246A (zh) * | 2021-10-19 | 2023-04-21 | 上海高科生物工程有限公司 | 一种兼具抗幽门螺旋杆菌和胃黏膜修复功能的蛋白组合物及其应用 |
| CN115252460B (zh) * | 2022-08-18 | 2024-07-09 | 媞颂日化用品(广州)有限公司 | 一种含抗菌肽的祛痘组合物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1197924B (it) * | 1986-10-28 | 1988-12-21 | Prodotti Antibiotici Spa | Procedimento per la preparazione di alimenti di origine animale |
| DE3701565A1 (de) * | 1987-01-21 | 1988-08-04 | Hoechst Ag | Verwendung von bakterienlysierendem enzymprodukt aus streptomyceten zur haltbarmachung von frischfleisch |
-
1989
- 1989-12-11 CA CA002005122A patent/CA2005122A1/en not_active Abandoned
- 1989-12-13 NZ NZ231764A patent/NZ231764A/en unknown
- 1989-12-19 AU AU46860/89A patent/AU620481B2/en not_active Ceased
- 1989-12-19 EP EP89123445A patent/EP0374823B1/en not_active Expired - Lifetime
- 1989-12-19 ES ES89123445T patent/ES2047100T3/es not_active Expired - Lifetime
- 1989-12-19 JP JP1327455A patent/JPH02283269A/ja active Pending
- 1989-12-19 DE DE89123445T patent/DE68911279T2/de not_active Expired - Fee Related
- 1989-12-20 MX MX018817A patent/MX170613B/es unknown
- 1989-12-20 DK DK649689A patent/DK649689A/da not_active Application Discontinuation
- 1989-12-20 AR AR89315756A patent/AR243743A1/es active
- 1989-12-21 NO NO895186A patent/NO174793B/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0374823A2 (en) | 1990-06-27 |
| EP0374823B1 (en) | 1993-12-08 |
| ES2047100T3 (es) | 1994-02-16 |
| AU4686089A (en) | 1990-06-28 |
| DE68911279T2 (de) | 1994-03-31 |
| NO895186L (no) | 1990-06-22 |
| NO895186D0 (no) | 1989-12-21 |
| NO174793C (OSRAM) | 1994-07-13 |
| NZ231764A (en) | 1992-06-25 |
| MX170613B (es) | 1993-09-01 |
| JPH02283269A (ja) | 1990-11-20 |
| DK649689A (da) | 1990-06-22 |
| EP0374823A3 (en) | 1990-12-12 |
| AU620481B2 (en) | 1992-02-20 |
| NO174793B (no) | 1994-04-05 |
| DE68911279D1 (de) | 1994-01-20 |
| AR243743A1 (es) | 1993-09-30 |
| DK649689D0 (da) | 1989-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 19960611 |