CA2003198A1 - Solutions ophtalmiques aqueuses et methode de conservation - Google Patents

Solutions ophtalmiques aqueuses et methode de conservation

Info

Publication number
CA2003198A1
CA2003198A1 CA2003198A CA2003198A CA2003198A1 CA 2003198 A1 CA2003198 A1 CA 2003198A1 CA 2003198 A CA2003198 A CA 2003198A CA 2003198 A CA2003198 A CA 2003198A CA 2003198 A1 CA2003198 A1 CA 2003198A1
Authority
CA
Canada
Prior art keywords
chlorine dioxide
stabilized chlorine
ophthalmic solutions
solutions
ophthalmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2003198A
Other languages
English (en)
Other versions
CA2003198C (fr
Inventor
Anthony J. Dziabo, Jr.
Paul S. Ripley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23062361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2003198(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CA2003198A1 publication Critical patent/CA2003198A1/fr
Application granted granted Critical
Publication of CA2003198C publication Critical patent/CA2003198C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/20Elemental chlorine; Inorganic compounds releasing chlorine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/10Halogens or compounds thereof
    • A61L12/102Chlorine dioxide (ClO2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Audible-Bandwidth Dynamoelectric Transducers Other Than Pickups (AREA)
  • Fats And Perfumes (AREA)
CA002003198A 1988-11-29 1989-11-17 Solutions ophtalmiques aqueuses et methode de conservation Expired - Lifetime CA2003198C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27779188A 1988-11-29 1988-11-29
US277,791 1988-11-29

Publications (2)

Publication Number Publication Date
CA2003198A1 true CA2003198A1 (fr) 1990-05-29
CA2003198C CA2003198C (fr) 1995-03-21

Family

ID=23062361

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002003198A Expired - Lifetime CA2003198C (fr) 1988-11-29 1989-11-17 Solutions ophtalmiques aqueuses et methode de conservation

Country Status (20)

Country Link
US (1) US5424078A (fr)
EP (1) EP0371728B1 (fr)
JP (1) JP2820744B2 (fr)
KR (1) KR0160443B1 (fr)
CN (1) CN1055874A (fr)
AT (1) ATE147230T1 (fr)
AU (1) AU621689B2 (fr)
CA (1) CA2003198C (fr)
DE (1) DE68927631T2 (fr)
DK (1) DK593989A (fr)
ES (1) ES2098226T3 (fr)
FI (1) FI895700A0 (fr)
HK (1) HK1005164A1 (fr)
HU (1) HU206455B (fr)
IE (1) IE81090B1 (fr)
IL (1) IL92351A (fr)
NO (1) NO894740L (fr)
NZ (1) NZ231458A (fr)
PT (1) PT92453B (fr)
ZA (1) ZA898824B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343949B2 (en) 2004-06-09 2013-01-01 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent, and an oxidizing preservative

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4997626A (en) * 1990-01-05 1991-03-05 Allergan, Inc. Methods to disinfect contact lenses
CA2152077A1 (fr) * 1992-12-17 1994-06-23 Anthony P. Frangione Solution de desinfection de verres de contact renfermant du chlorite de sodium et de la polyvinylpyrrolidone
US5736165A (en) * 1993-05-25 1998-04-07 Allergan In-the-eye use of chlorine dioxide-containing compositions
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
US6024954A (en) * 1994-12-12 2000-02-15 Allergan Compositions and methods for disinfecting contact lenses and preserving contact lens care products
US5858346A (en) * 1997-05-09 1999-01-12 Allergan Compositions and methods for enhancing contact lens wearability
JP2002523475A (ja) * 1998-09-02 2002-07-30 アラーガン・セイルズ・インコーポレイテッド 防腐したシクロデキストリン含有組成物
MXPA01003507A (es) * 1998-10-08 2002-06-26 Hampar L Karagoezian Antimicrobiano sinergico, preparaciones dermatologicas y oftalmicas que contienen clorito y peroxido de hidrogeno.
US20040037891A1 (en) * 1999-10-04 2004-02-26 Karagoezian Hampar L. Synergistic antimicrobial ophthalmic and dermatologic preparations containing chlorite and hydrogen peroxide
US20050026924A1 (en) * 2000-07-14 2005-02-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US8858961B2 (en) 2000-07-14 2014-10-14 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
WO2002063968A2 (fr) 2001-02-09 2002-08-22 Bioxy, Inc. Compositions biocides congelees et methodes d'utilisation associees
US7176005B2 (en) * 2002-02-04 2007-02-13 The Regents Of The University Of California Modulation of sulfate permease for photosynthetic hydrogen production
US7030149B2 (en) * 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
US20040137079A1 (en) * 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
US20040191332A1 (en) * 2003-03-27 2004-09-30 Allergan, Inc. Preserved ophthalmic compositions
US7439241B2 (en) * 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
CA2505836C (fr) * 2004-05-06 2013-08-27 Alcon Inc. Formulations topiques de tartrate de brimonidine exemptes de dioxyde de chlore
JP4955543B2 (ja) 2004-05-25 2012-06-20 サンズローザ ファーマシューティカル ディヴェロップメント インコーポレイテッド 炎症性皮膚疾患を治療又は予防するための化合物、製剤及び方法
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US8703198B2 (en) * 2005-03-02 2014-04-22 Aquatrove Biosciences Water-based personal moisturizers and lubricants, in particular vaginal lubricants, and uses thereof
CA2628570A1 (fr) 2005-11-09 2007-05-18 Combinatorx, Incorporated Procedes, compositions et kits pour le traitement de pathologies
US7960447B2 (en) * 2006-04-13 2011-06-14 Bausch & Lomb Incorporated Cationic end-capped siloxane prepolymer for reduced cross-link density
US20070297990A1 (en) * 2006-06-27 2007-12-27 Shah Mandar V Self-preserving composition
US20100021561A1 (en) * 2006-09-21 2010-01-28 Chowhan Masood A Self-preserved aqueous pharmaceutical compositions
TWI394564B (zh) * 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
KR101421519B1 (ko) * 2006-09-28 2014-07-30 알콘 리서치, 리미티드 자기 보존 수성 약제학적 조성물
UY31059A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado
US20110224215A1 (en) 2007-12-21 2011-09-15 Galderma Laboratories, Inc. Pre-surgical treatment
DK2420223T3 (da) * 2008-03-17 2017-11-06 Novartis Ag Vandige farmaceutiske sammensætninger med borat-polyol-komplekser
CL2009001581A1 (es) 2008-07-15 2010-09-10 Basf Corp Metodo para pulir una superficie dental, donde se pone en contacto dicha superficie con una composicion de pulido sustancialmente no irritante y comprende dioxido de cloro;
MX2011000536A (es) * 2008-07-15 2011-03-15 Basf Corp Fluidos no citotoxicos de dioxido de cloro.
US20100197694A1 (en) * 2008-08-01 2010-08-05 Gerald Horn Compositions and methods for treatment of diseases and conditions with increased vascular permeability
US20100203165A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US20100202979A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US20110003823A1 (en) * 2008-08-01 2011-01-06 Alpha Synergy Development, Inc. Compositions and methods for treatment of diseases and conditions associated with vasodilation and/or vascular leakage
US20100029662A1 (en) * 2008-08-01 2010-02-04 Alpha Synergy Development, Inc. Vasoconstriction compositions and methods of use
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
US20100196512A1 (en) 2009-02-04 2010-08-05 Basf Catalyst Llc Treatment of Non-Oral Biological Tissue with Chlorine Dioxide
TW201105369A (en) * 2009-05-29 2011-02-16 Alcon Res Ltd N-halamine formulations with enhanced antimicrobial activity
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸-多元醇錯合物之水性藥學組成物
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof
US8992831B2 (en) 2009-09-25 2015-03-31 E. I. Du Pont De Nemours And Company Stabilized chlorine dioxide to preserve carbohydrate feedstocks
EP2329849B1 (fr) 2009-11-18 2015-04-29 Galderma Research & Development Combinaison d'un agoniste du récepteur alpha-2 adrénergique et d'un agent anti-inflammatoire non stéroïdien pour traiter ou empêcher un trouble cutané inflammatoire
US8394800B2 (en) 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
WO2011075621A1 (fr) * 2009-12-17 2011-06-23 Alpha Synergy Development, Inc. Compositions et méthodes d'administration ophtalmique de décongestionnants nasals
US8916562B2 (en) 2010-03-26 2014-12-23 Galderma Research & Development Snc Methods and compositions for safe and effective treatment of telangiectasia
KR20170018974A (ko) 2010-03-26 2017-02-20 갈데르마 리써어치 앤드 디벨로프먼트 홍반의 유효하고 안전한 치료를 위한 개선된 방법 및 조성물
WO2012001064A2 (fr) 2010-06-30 2012-01-05 Galderma Research & Development Procédé de prévention ou de traitement des tumeurs cutanées
US8911713B2 (en) 2010-06-30 2014-12-16 Galderma Research & Development Method for preventing or treating skin tumor
SG189896A1 (en) 2010-10-21 2013-06-28 Galderma Sa Brimonidine gel compositions and methods of use
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
US8445526B2 (en) 2011-02-03 2013-05-21 Glaucoma & Nasal Therapies Llc Compositions and methods for treatment of glaucoma
US20150044148A1 (en) 2011-10-19 2015-02-12 Galderma Laboratories, Inc. Method for Treating Capillary Hemangiomas
JP2014530846A (ja) 2011-10-19 2014-11-20 ガルデルマ ソシエテ アノニム ホスホジエステラーゼ5型阻害薬の全身使用に伴う顔面潮紅の軽減方法
US20140127327A1 (en) * 2012-11-08 2014-05-08 Allergan, Inc. Preserved topical formulations with improved antimicrobial activity
US20150031712A1 (en) * 2013-03-12 2015-01-29 Moshe Rogosnitzky Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same
US8999938B2 (en) 2013-06-21 2015-04-07 Gnt Llc Ophthalmic lipophilic drug delivery vehicle formulations
RU2690183C2 (ru) 2013-09-26 2019-05-31 Галдерма С.А. Простагландин f2 альфа и его аналоги для лечения атрофического кожного рубцевания
EA030615B1 (ru) 2013-12-24 2018-08-31 Сентисс Фарма Прайвет Лимитед Офтальмологический раствор бримонидина для местного применения
EP4420726A3 (fr) * 2015-03-19 2024-11-13 Allergan, Inc. Combinaison de doses fixes de bromonidine et de timolol
WO2017210454A1 (fr) * 2016-06-03 2017-12-07 The Regents Of The University Of Colorado, A Body Corporate Agent désinfectant ophtalmique et méthodes d'utilisation associées
CN106265797A (zh) * 2016-09-18 2017-01-04 成都测迪森生物科技有限公司 一种洗眼液
CN108310442B (zh) * 2017-01-17 2021-08-27 台北科技大学 眼科用组合物
GR1009419B (el) 2017-11-07 2018-12-14 Φαρματεν Αβεε Οφθαλμικο φαρμακευτικο σκευασμα που περιεχει εναν συνδυασμο βρινζολαμιδης και βριμονιδινης και μεθοδος για την παρασκευη αυτου
SI3681500T1 (sl) 2018-04-24 2022-09-30 Allergan, Inc. Uporaba pilokarpinijevega hidroklorida za zdravljenje presbiopije
EP3784354A1 (fr) * 2018-04-27 2021-03-03 Allergan, Inc. Compositions de chlorite de sodium possédant une efficacité antimicrobienne améliorée et une toxicité réduite
US11077053B2 (en) 2018-08-21 2021-08-03 Allergan, Inc. Alpha-2-adrenergic receptor agonists for treatment of presbyopia, visual glare, visual starbursts, visual halos and night myopia
EP4142689A1 (fr) 2020-04-29 2023-03-08 Sentiss Pharma Private Limited Compositions ophtalmiques comprenant une combinaison de brinzolamide et de brimonidine
CN113419360A (zh) * 2021-06-23 2021-09-21 武汉爱尔眼科汉口医院有限公司 角膜塑形镜试戴片污染状况调查与干预措施
CN116135021A (zh) * 2021-11-17 2023-05-19 陈力瑜 杀菌组成物
WO2024243373A1 (fr) 2023-05-24 2024-11-28 Lento Bio, Inc. Dérivés de cystéine pour le traitement de la presbytie

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123521A (en) * 1964-03-03
USRE23218E (en) * 1945-02-21 1950-04-11 Catalytic bleaching with chlorites
US2436134A (en) * 1945-03-12 1948-02-17 Mathieson Alkali Works Inc Production of chlorine dioxide
US3278447A (en) * 1963-12-02 1966-10-11 Cloro Bac Products Inc Process for stabilizing chlorine dioxide solution
US3591515A (en) * 1968-04-16 1971-07-06 Int Dioxide Inc Pulverulent chlorine dioxide compositions
GB1269677A (en) * 1969-12-11 1972-04-06 Procter & Gamble Ltd Bleaching composition
US3819828A (en) * 1973-02-16 1974-06-25 Procter & Gamble Anhydrous hair treating product containing a monopersulfate salt
US3910296A (en) * 1973-04-20 1975-10-07 Allergan Pharma Method of removing proteinaceous deposits from contact lenses
US4123376A (en) * 1973-08-24 1978-10-31 Colgate-Palmolive Company Peroxymonosulfate-base bleaching and bleaching detergent compositions
GB1579431A (en) * 1976-03-23 1980-11-19 Minnesota Mining & Mfg Disinfecting and/or sterilising
US4084747A (en) * 1976-03-26 1978-04-18 Howard Alliger Germ killing composition and method
JPS596915B2 (ja) * 1980-05-13 1984-02-15 日本カ−リツト株式会社 二酸化塩素の電解製造方法
US4499077A (en) * 1981-02-03 1985-02-12 Stockel Richard F Anti-microbial compositions and associated methods for preparing the same and for the disinfecting of various objects
US4459217A (en) * 1981-07-22 1984-07-10 Reckitt & Colman Products Limited Denture cleansing compositions
US4654208A (en) * 1983-03-01 1987-03-31 Stockel Richard F Anti-microbial compositions comprising an aqueous solution of a germicidal polymeric nitrogen compound and a potentiating oxidizing agent
GB2139260B (en) * 1983-05-04 1986-09-03 Unilever Plc Bleaching and cleaning composition
US4568517A (en) * 1983-08-25 1986-02-04 Barnes-Hind, Inc. Disinfection of contact lenses
US4690773A (en) * 1983-10-24 1987-09-01 Bausch & Lomb Incorporated Microbial enzymatic contact lens cleaner and methods of use
US4614549A (en) * 1983-10-24 1986-09-30 Bausch & Lomb Incorporated Method for enzymatic cleaning and disinfecting contact lenses
IN160430B (fr) * 1984-03-18 1987-07-11 Alcide Corp
US4613332A (en) * 1984-07-11 1986-09-23 The Clorox Company Controlled generation hypochlorite compositions and method
US4689215A (en) * 1984-07-30 1987-08-25 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4837009A (en) * 1986-03-31 1989-06-06 Ratcliff Perry A Method and composition for prevention of plaque formation and plaque dependent diseases
US4788053A (en) * 1984-07-30 1988-11-29 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4793989A (en) * 1984-07-30 1988-12-27 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4855135A (en) * 1984-07-30 1989-08-08 Ratcliff Perry A Method for debriding
US4696811A (en) * 1984-07-30 1987-09-29 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4618444A (en) * 1984-09-17 1986-10-21 Purex Corporation Household laundry detergent with dual strength bleach
GB8507678D0 (en) * 1985-03-25 1985-05-01 Univ Bath Cleaning/disinfection of contact lenses
DE3669528D1 (de) * 1985-03-26 1990-04-19 Toray Industries Reinigungssystem fuer kontaktlinsen und verfahren zu deren reinigung.
GB8508010D0 (en) * 1985-03-27 1985-05-01 Unilever Plc Liquid bleaching compositions
USRE32672E (en) * 1985-09-09 1988-05-24 Allergan, Inc. Method for simultaneously cleaning and disinfecting contact lenses using a mixture of peroxide and proteolytic enzyme
GB2187748A (en) * 1986-03-07 1987-09-16 Unilever Plc Bleaching fabrics
US4851213A (en) * 1986-03-31 1989-07-25 Ratcliff Perry A Method and composition for prevention and treatment of oral disease due to S. Sanguis
US4786492A (en) * 1986-03-31 1988-11-22 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
DE3704823A1 (de) * 1987-02-16 1988-09-15 Thilo & Co Gmbh Dr Kontaktlinsenpflegemittel mit desinfizierender und reinigender wirkung
JPH0678769B2 (ja) * 1987-04-13 1994-10-05 石川島播磨重工業株式会社 セラミック軸受取付構造

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343949B2 (en) 2004-06-09 2013-01-01 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent, and an oxidizing preservative
US8691802B2 (en) 2004-06-09 2014-04-08 Allergan, Inc. Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative

Also Published As

Publication number Publication date
PT92453A (pt) 1990-05-31
KR900007427A (ko) 1990-06-01
CN1055874A (zh) 1991-11-06
FI895700A0 (fi) 1989-11-28
DE68927631D1 (de) 1997-02-20
NZ231458A (en) 1992-01-29
IE893780L (en) 1990-05-29
NO894740L (no) 1990-05-30
DE68927631T2 (de) 1997-08-21
HU896225D0 (en) 1990-02-28
IL92351A (en) 1994-02-27
ES2098226T3 (es) 1997-05-01
KR0160443B1 (ko) 1998-12-01
AU4549989A (en) 1990-06-07
HK1005164A1 (en) 1998-12-24
PT92453B (pt) 1995-07-18
HUT52706A (en) 1990-08-28
DK593989D0 (da) 1989-11-24
NO894740D0 (no) 1989-11-28
EP0371728B1 (fr) 1997-01-08
AU621689B2 (en) 1992-03-19
CA2003198C (fr) 1995-03-21
ATE147230T1 (de) 1997-01-15
DK593989A (da) 1990-05-30
US5424078A (en) 1995-06-13
HU206455B (en) 1992-11-30
IE81090B1 (en) 2000-03-08
JPH02184631A (ja) 1990-07-19
EP0371728A1 (fr) 1990-06-06
IL92351A0 (en) 1990-07-26
JP2820744B2 (ja) 1998-11-05
ZA898824B (en) 1990-08-29

Similar Documents

Publication Publication Date Title
AU4549989A (en) Aqueous ophthalmic solutions and method for preserving same
IE822327L (en) Ophthalmic irrigating solution
BG100915A (en) Ophthalmic composition with decreased viscosity
NO174795C (fr)
CA2059403A1 (fr) Utilisation de carragenines dans des compositions ophtalmiques a application topique
CA2138157A1 (fr) Dispersion plastique comestible comportant une fecule a prise rapide
WO2002026277A3 (fr) Solutions stabilisees de peroxyde d'hydrogene
IE891118L (en) Topical preparation for treating otopathy
EP0293766A3 (fr) Emulsions
IN171579B (fr)
ATE416790T1 (de) Wasserlösliche trockene zusammensetzungen
TW255822B (fr)
JPS5762218A (en) Ophthalmic solution
EP0356367A3 (fr) Milieu liquide pour l'infusion et pour la conservation d'organes
DK0419165T3 (da) Konserveringsmiddel til anvendelse i ophthalmiske opløsninger
GR3005100T3 (fr)
AU9095291A (en) Sterilising composition
AU3026589A (en) A solution of carboplatin
CA2113486A1 (fr) Substituts hyposodiques comestibles

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry