CA1276025C - Aminoalkylpyridineamides - Google Patents

Aminoalkylpyridineamides

Info

Publication number
CA1276025C
CA1276025C CA000500834A CA500834A CA1276025C CA 1276025 C CA1276025 C CA 1276025C CA 000500834 A CA000500834 A CA 000500834A CA 500834 A CA500834 A CA 500834A CA 1276025 C CA1276025 C CA 1276025C
Authority
CA
Canada
Prior art keywords
thio
methyl
compound
dimethylethyl
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000500834A
Other languages
English (en)
French (fr)
Inventor
Richard A. Mueller
Richard A. Partis
James R. Deason
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of CA1276025C publication Critical patent/CA1276025C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000500834A 1985-02-04 1986-01-31 Aminoalkylpyridineamides Expired - Lifetime CA1276025C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69804885A 1985-02-04 1985-02-04
US06/698,048 1985-02-04
US06/809,955 1985-12-20
US06/809,955 US4663333A (en) 1985-02-04 1985-12-20 Acylaminoalkylpyridines ad use in treatment of inflammation and allergy reactions

Publications (1)

Publication Number Publication Date
CA1276025C true CA1276025C (en) 1990-11-06

Family

ID=27106141

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000500834A Expired - Lifetime CA1276025C (en) 1985-02-04 1986-01-31 Aminoalkylpyridineamides

Country Status (6)

Country Link
US (1) US4663333A (de)
EP (1) EP0190683B1 (de)
JP (1) JPH0730024B2 (de)
AU (1) AU584971B2 (de)
CA (1) CA1276025C (de)
DE (1) DE3686729T2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002967A (en) * 1987-06-05 1991-03-26 G. D. Searle & Co. Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase
CA1327050C (en) * 1987-06-05 1994-02-15 Richard August Mueller Phenolic thioethers, sulfoxides, and disulfides as inhibitors of 5-lipoxygenase
JP2754039B2 (ja) * 1988-06-24 1998-05-20 塩野義製薬株式会社 ジ―ｔｅｒｔ―ブチルヒドロキシフェニルチオ誘導体
US5030642A (en) * 1988-12-02 1991-07-09 G. D. Searle & Co. Acylaminoalkylpyridineamides as inhibitors of metastasis
ES2010145A6 (es) * 1989-03-02 1989-10-16 Uriach & Cia Sa J Procedimiento para la obtencion de derivados de la 2-picolilamina.
US5189038A (en) * 1990-09-07 1993-02-23 G. D. Searle And Co. Method of stimulating superoxide generation
US5082854A (en) * 1990-09-07 1992-01-21 G. D. Searle & Co. Method of stimulating superoxide generation
AU8440991A (en) * 1990-09-07 1992-03-30 G.D. Searle & Co. Phenolic thioetheramides as 5-lipoxygenase inhibitors
US9321724B2 (en) * 2012-03-28 2016-04-26 Intervet Inc. Heteroaryl compounds with A-cyclic bridging unit

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2899437A (en) * 1959-08-11 Pyridylethylated salicylamides
US3931200A (en) * 1974-01-22 1976-01-06 The Dow Chemical Company Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas
JPS6039262B2 (ja) * 1977-05-11 1985-09-05 ウェルファイド株式会社 第３級ブチルフェノ−ル誘導体
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU5288486A (en) 1986-08-07
EP0190683B1 (de) 1992-09-16
JPS61210073A (ja) 1986-09-18
EP0190683A3 (en) 1987-08-26
AU584971B2 (en) 1989-06-08
US4663333A (en) 1987-05-05
EP0190683A2 (de) 1986-08-13
DE3686729D1 (de) 1992-10-22
JPH0730024B2 (ja) 1995-04-05
DE3686729T2 (de) 1993-03-04

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Legal Events

Date Code Title Description
MKLA Lapsed
MKLA Lapsed

Effective date: 19960506