CA1260183A - Glass-filled, absorbable surgical devices - Google Patents
Glass-filled, absorbable surgical devicesInfo
- Publication number
- CA1260183A CA1260183A CA000466687A CA466687A CA1260183A CA 1260183 A CA1260183 A CA 1260183A CA 000466687 A CA000466687 A CA 000466687A CA 466687 A CA466687 A CA 466687A CA 1260183 A CA1260183 A CA 1260183A
- Authority
- CA
- Canada
- Prior art keywords
- glass
- polymer
- absorbable
- staple
- staples
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000011521 glass Substances 0.000 title claims abstract description 33
- 229920000642 polymer Polymers 0.000 claims abstract description 31
- 239000005365 phosphate glass Substances 0.000 claims description 5
- 239000012763 reinforcing filler Substances 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 3
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 claims description 2
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 claims description 2
- 239000011777 magnesium Substances 0.000 claims description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000000945 filler Substances 0.000 abstract description 7
- 230000001965 increasing effect Effects 0.000 description 7
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 239000000835 fiber Substances 0.000 description 6
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 239000000395 magnesium oxide Substances 0.000 description 4
- 229910019142 PO4 Inorganic materials 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 229910000287 alkaline earth metal oxide Inorganic materials 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 239000000292 calcium oxide Substances 0.000 description 3
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 3
- 230000004927 fusion Effects 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 239000010419 fine particle Substances 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000006060 molten glass Substances 0.000 description 2
- 239000008188 pellet Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- CHWRSCGUEQEHOH-UHFFFAOYSA-N potassium oxide Chemical compound [O-2].[K+].[K+] CHWRSCGUEQEHOH-UHFFFAOYSA-N 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- KKCBUQHMOMHUOY-UHFFFAOYSA-N sodium oxide Chemical compound [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 101000843155 Capsicum annuum Histone H4 Proteins 0.000 description 1
- 241001379910 Ephemera danica Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 229910000272 alkali metal oxide Inorganic materials 0.000 description 1
- 229910000148 ammonium phosphate Inorganic materials 0.000 description 1
- 235000019289 ammonium phosphates Nutrition 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 239000000316 bone substitute Substances 0.000 description 1
- YYRMJZQKEFZXMX-UHFFFAOYSA-L calcium bis(dihydrogenphosphate) Chemical compound [Ca+2].OP(O)([O-])=O.OP(O)([O-])=O YYRMJZQKEFZXMX-UHFFFAOYSA-L 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 229910052681 coesite Inorganic materials 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000000748 compression moulding Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 229910052906 cristobalite Inorganic materials 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- MHJAJDCZWVHCPF-UHFFFAOYSA-L dimagnesium phosphate Chemical compound [Mg+2].OP([O-])([O-])=O MHJAJDCZWVHCPF-UHFFFAOYSA-L 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000010902 jet-milling Methods 0.000 description 1
- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 description 1
- 239000004137 magnesium phosphate Substances 0.000 description 1
- 229960002261 magnesium phosphate Drugs 0.000 description 1
- 229910000157 magnesium phosphate Inorganic materials 0.000 description 1
- 235000010994 magnesium phosphates Nutrition 0.000 description 1
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 1
- 210000004373 mandible Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000002074 melt spinning Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910000150 monocalcium phosphate Inorganic materials 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000000622 polydioxanone Substances 0.000 description 1
- 229910052573 porcelain Inorganic materials 0.000 description 1
- 229910001950 potassium oxide Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229920005604 random copolymer Polymers 0.000 description 1
- 238000002271 resection Methods 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 description 1
- 235000019982 sodium hexametaphosphate Nutrition 0.000 description 1
- 229910001948 sodium oxide Inorganic materials 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 229910052682 stishovite Inorganic materials 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 229910052905 tridymite Inorganic materials 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- LRXTYHSAJDENHV-UHFFFAOYSA-H zinc phosphate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LRXTYHSAJDENHV-UHFFFAOYSA-H 0.000 description 1
- 229910000165 zinc phosphate Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/064—Surgical staples, i.e. penetrating the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/127—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing fillers of phosphorus-containing inorganic materials
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/557,038 US4612923A (en) | 1983-12-01 | 1983-12-01 | Glass-filled, absorbable surgical devices |
| US557,038 | 1983-12-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1260183A true CA1260183A (en) | 1989-09-26 |
Family
ID=24223813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000466687A Expired CA1260183A (en) | 1983-12-01 | 1984-10-31 | Glass-filled, absorbable surgical devices |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4612923A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0144228B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS60135038A (cg-RX-API-DMAC7.html) |
| AR (1) | AR242967A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU570748B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR8406096A (cg-RX-API-DMAC7.html) |
| CA (1) | CA1260183A (cg-RX-API-DMAC7.html) |
| DE (1) | DE3481161D1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK567984A (cg-RX-API-DMAC7.html) |
| MX (1) | MX163279B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA849365B (cg-RX-API-DMAC7.html) |
Families Citing this family (126)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4655777A (en) * | 1983-12-19 | 1987-04-07 | Southern Research Institute | Method of producing biodegradable prosthesis and products therefrom |
| DE3445738A1 (de) * | 1984-12-14 | 1986-06-19 | Draenert Klaus | Implantat zur knochenverstaerkung und verankerung von knochenschrauben, implantaten oder implantatteilen |
| US4973333A (en) * | 1985-09-20 | 1990-11-27 | Richards Medical Company | Resorbable compressing screw and method |
| US4776329A (en) * | 1985-09-20 | 1988-10-11 | Richards Medical Company | Resorbable compressing screw and method |
| FI81010C (fi) * | 1986-09-05 | 1990-09-10 | Biocon Oy | Stoedstruktur foer bentransplantat. |
| FI81498C (fi) * | 1987-01-13 | 1990-11-12 | Biocon Oy | Kirurgiska material och instrument. |
| US4756307A (en) * | 1987-02-09 | 1988-07-12 | Zimmer, Inc. | Nail device |
| US4719917A (en) * | 1987-02-17 | 1988-01-19 | Minnesota Mining And Manufacturing Company | Surgical staple |
| FR2612392A1 (fr) * | 1987-03-19 | 1988-09-23 | Audion Michel | Composites biodegradables interrompus a resistance variable |
| DE3789876T2 (de) * | 1987-11-03 | 1994-11-03 | Synthes Ag | Knochenplatte mit konischen Löchern. |
| US4944742A (en) * | 1988-06-06 | 1990-07-31 | Johnson & Johnson Orthopaedics, Inc. | Bone pin |
| US5522817A (en) * | 1989-03-31 | 1996-06-04 | United States Surgical Corporation | Absorbable surgical fastener with bone penetrating elements |
| US5389102A (en) * | 1990-09-13 | 1995-02-14 | United States Surgical Corporation | Apparatus and method for subcuticular stapling of body tissue |
| US5423856A (en) * | 1990-09-13 | 1995-06-13 | United States Surgical Corporation | Apparatus and method for subcuticular stapling of body tissue |
| CA2049123C (en) * | 1990-09-13 | 2002-01-15 | David T. Green | Apparatus and method for subcuticular stapling of body tissue |
| CA2060635A1 (en) * | 1991-02-12 | 1992-08-13 | Keith D'alessio | Bioabsorbable medical implants |
| CA2063159C (en) * | 1991-03-22 | 1999-06-15 | Thomas W. Sander | Orthopedic fastener |
| US5252523A (en) * | 1991-10-09 | 1993-10-12 | Corning Incorporated | Bioabsorbable chlorophosphate glasses and bioabsorbable glass-polymer blends made therefrom |
| FR2689400B1 (fr) * | 1992-04-03 | 1995-06-23 | Inoteb | Materiau pour prothese osseuse contenant des particules de carbonate de calcium dispersees dans une matrice polymere bioresorbable. |
| US5464416A (en) * | 1992-11-10 | 1995-11-07 | Ethicon, Inc. | Ligating clip |
| US5397816A (en) * | 1992-11-17 | 1995-03-14 | Ethicon, Inc. | Reinforced absorbable polymers |
| DE19518796A1 (de) * | 1995-05-22 | 1996-11-28 | Hoechst Ag | Fluorphenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| CN1149596A (zh) * | 1995-08-23 | 1997-05-14 | 联合碳化化学品及塑料技术公司 | 稳定的二噁烷酮聚合物 |
| DE19614421C2 (de) * | 1996-04-12 | 1999-12-16 | Biovision Gmbh | Verfahren zur Herstellung eines biodegradierbaren Knochenersatz- und Implantatwerkstoffes und biodegradierbarer Knochenersatz- und Implantatwerkstoff |
| JP3731839B2 (ja) * | 1996-04-30 | 2006-01-05 | 株式会社クレハ | ポリグリコール酸射出成形物及びその製造方法 |
| US5874509A (en) * | 1996-07-05 | 1999-02-23 | Clemson University | Surface modified glasses and composites thereof |
| US5948000A (en) * | 1996-10-03 | 1999-09-07 | United States Surgical Corporation | System for suture anchor placement |
| CA2217406C (en) * | 1996-10-04 | 2006-05-30 | United States Surgical Corporation | Suture anchor installation system with disposable loading unit |
| EP0834280B1 (en) * | 1996-10-04 | 2004-01-02 | United States Surgical Corporation | Tissue fastener implantation apparatus |
| US7541049B1 (en) * | 1997-09-02 | 2009-06-02 | Linvatec Biomaterials Oy | Bioactive and biodegradable composites of polymers and ceramics or glasses and method to manufacture such composites |
| US5902319A (en) * | 1997-09-25 | 1999-05-11 | Daley; Robert J. | Bioabsorbable staples |
| US6090131A (en) * | 1997-09-25 | 2000-07-18 | Daley; Robert J. | Bioabsorbable staples |
| GB9811663D0 (en) * | 1998-06-01 | 1998-07-29 | Giltech Ltd | Composition |
| US5993452A (en) * | 1998-08-24 | 1999-11-30 | Biomet Inc. | Cerclage system |
| US6406498B1 (en) | 1998-09-04 | 2002-06-18 | Bionx Implants Oy | Bioactive, bioabsorbable surgical composite material |
| US6120526A (en) * | 1999-01-29 | 2000-09-19 | Daley; Robert J. | Delivery devices for bioabsorbable staples |
| US6783529B2 (en) | 1999-04-09 | 2004-08-31 | Depuy Orthopaedics, Inc. | Non-metal inserts for bone support assembly |
| US6296645B1 (en) | 1999-04-09 | 2001-10-02 | Depuy Orthopaedics, Inc. | Intramedullary nail with non-metal spacers |
| US20040009228A1 (en) * | 1999-11-30 | 2004-01-15 | Pertti Tormala | Bioabsorbable drug delivery system for local treatment and prevention of infections |
| US6579533B1 (en) | 1999-11-30 | 2003-06-17 | Bioasborbable Concepts, Ltd. | Bioabsorbable drug delivery system for local treatment and prevention of infections |
| US6808527B2 (en) | 2000-04-10 | 2004-10-26 | Depuy Orthopaedics, Inc. | Intramedullary nail with snap-in window insert |
| US6572623B1 (en) | 2000-07-25 | 2003-06-03 | Medtronic Ps Medical, Inc. | Method and apparatus for attaching a cranial flap |
| CA2418380A1 (en) * | 2000-08-17 | 2002-02-21 | Tyco Healthcare Group Lp | Sutures and coatings made from therapeutic absorbable glass |
| DE60113871T2 (de) * | 2000-11-01 | 2006-07-27 | Medi-Physics, Inc., Arlington Heights | Verfahren zur herstellung eines radioaktiven elementes zur brachytherapie |
| US7776310B2 (en) | 2000-11-16 | 2010-08-17 | Microspherix Llc | Flexible and/or elastic brachytherapy seed or strand |
| US7005135B2 (en) * | 2001-01-30 | 2006-02-28 | Ethicon Inc. | Glass scaffolds with controlled resorption rates and methods for making same |
| GB0124742D0 (en) * | 2001-10-16 | 2001-12-05 | Biocomposites Ltd | Biodegradable materials |
| US10285694B2 (en) | 2001-10-20 | 2019-05-14 | Covidien Lp | Surgical stapler with timer and feedback display |
| US7464847B2 (en) | 2005-06-03 | 2008-12-16 | Tyco Healthcare Group Lp | Surgical stapler with timer and feedback display |
| US7074291B2 (en) * | 2001-11-02 | 2006-07-11 | Worldwide Medical Technologies, L.L.C. | Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings |
| US7060020B2 (en) | 2001-11-02 | 2006-06-13 | Ideamatrix, Inc. | Delivery system and method for interstitial radiation therapy |
| US10098640B2 (en) | 2001-12-04 | 2018-10-16 | Atricure, Inc. | Left atrial appendage devices and methods |
| US6974462B2 (en) | 2001-12-19 | 2005-12-13 | Boston Scientific Scimed, Inc. | Surgical anchor implantation device |
| US7322928B2 (en) | 2003-03-17 | 2008-01-29 | Medi-Physics, Inc. | Products and methods for brachytherapy |
| US7951176B2 (en) | 2003-05-30 | 2011-05-31 | Synthes Usa, Llc | Bone plate |
| EP1741397B1 (de) | 2003-08-26 | 2010-07-14 | Synthes GmbH | Knochenplatte |
| US11259851B2 (en) | 2003-08-26 | 2022-03-01 | DePuy Synthes Products, Inc. | Bone plate |
| CN100475168C (zh) * | 2003-09-08 | 2009-04-08 | 斯恩蒂斯有限公司 | 用于骨固定术的装置 |
| JP5031367B2 (ja) | 2003-09-23 | 2012-09-19 | オーソコン・インコーポレイテッド | 吸収性のインプラントならびに止血および骨欠損の処置における、それらの使用 |
| KR101136203B1 (ko) * | 2003-10-30 | 2012-04-17 | 신세스 게엠바하 | 뼈플레이트 |
| ES2379877T3 (es) | 2003-12-01 | 2012-05-04 | Smith & Nephew, Inc. | Clavo humeral con un inserto para fijar un tornillo |
| US7637928B2 (en) | 2004-01-26 | 2009-12-29 | Synthes Usa, Llc | Variable angle locked bone fixation system |
| US11291484B2 (en) | 2004-01-26 | 2022-04-05 | DePuy Synthes Products, Inc. | Highly-versatile variable-angle bone plate system |
| US8574268B2 (en) | 2004-01-26 | 2013-11-05 | DePuy Synthes Product, LLC | Highly-versatile variable-angle bone plate system |
| US20060015144A1 (en) * | 2004-07-19 | 2006-01-19 | Vascular Control Systems, Inc. | Uterine artery occlusion staple |
| US20070038303A1 (en) * | 2006-08-15 | 2007-02-15 | Ebi, L.P. | Foot/ankle implant and associated method |
| US7879109B2 (en) * | 2004-12-08 | 2011-02-01 | Biomet Manufacturing Corp. | Continuous phase composite for musculoskeletal repair |
| US8535357B2 (en) * | 2004-12-09 | 2013-09-17 | Biomet Sports Medicine, Llc | Continuous phase compositions for ACL repair |
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-
1983
- 1983-12-01 US US06/557,038 patent/US4612923A/en not_active Expired - Lifetime
-
1984
- 1984-10-31 CA CA000466687A patent/CA1260183A/en not_active Expired
- 1984-11-28 JP JP59249813A patent/JPS60135038A/ja active Granted
- 1984-11-29 DK DK567984A patent/DK567984A/da not_active Application Discontinuation
- 1984-11-30 MX MX203560A patent/MX163279B/es unknown
- 1984-11-30 AR AR84298800A patent/AR242967A1/es active
- 1984-11-30 AU AU36087/84A patent/AU570748B2/en not_active Expired
- 1984-11-30 EP EP84308352A patent/EP0144228B1/en not_active Expired - Lifetime
- 1984-11-30 BR BR8406096A patent/BR8406096A/pt not_active IP Right Cessation
- 1984-11-30 DE DE8484308352T patent/DE3481161D1/de not_active Expired - Lifetime
- 1984-11-30 ZA ZA849365A patent/ZA849365B/xx unknown
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|---|---|
| BR8406096A (pt) | 1985-09-24 |
| EP0144228B1 (en) | 1990-01-31 |
| MX163279B (es) | 1992-03-31 |
| ZA849365B (en) | 1986-07-30 |
| JPS60135038A (ja) | 1985-07-18 |
| DK567984A (da) | 1985-06-02 |
| EP0144228A3 (en) | 1986-12-30 |
| AU3608784A (en) | 1985-06-06 |
| JPH0522548B2 (cg-RX-API-DMAC7.html) | 1993-03-29 |
| DE3481161D1 (de) | 1990-03-08 |
| US4612923A (en) | 1986-09-23 |
| AU570748B2 (en) | 1988-03-24 |
| EP0144228A2 (en) | 1985-06-12 |
| DK567984D0 (da) | 1984-11-29 |
| AR242967A1 (es) | 1993-06-30 |
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