CA1259374A - Capteur capacitif pour les analyses et les mesures chimiques - Google Patents

Capteur capacitif pour les analyses et les mesures chimiques

Info

Publication number
CA1259374A
CA1259374A CA000523122A CA523122A CA1259374A CA 1259374 A CA1259374 A CA 1259374A CA 000523122 A CA000523122 A CA 000523122A CA 523122 A CA523122 A CA 523122A CA 1259374 A CA1259374 A CA 1259374A
Authority
CA
Canada
Prior art keywords
binding
analyte
capacitor
conductor
biospecific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000523122A
Other languages
English (en)
Inventor
Arnold L. Newman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johns Hopkins University
Original Assignee
Johns Hopkins University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johns Hopkins University filed Critical Johns Hopkins University
Application granted granted Critical
Publication of CA1259374A publication Critical patent/CA1259374A/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
    • G01N27/227—Sensors changing capacitance upon adsorption or absorption of fluid components, e.g. electrolyte-insulator-semiconductor sensors, MOS capacitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA000523122A 1985-11-19 1986-11-17 Capteur capacitif pour les analyses et les mesures chimiques Expired CA1259374A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79976185A 1985-11-19 1985-11-19
US799,761 1985-11-19

Publications (1)

Publication Number Publication Date
CA1259374A true CA1259374A (fr) 1989-09-12

Family

ID=25176687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000523122A Expired CA1259374A (fr) 1985-11-19 1986-11-17 Capteur capacitif pour les analyses et les mesures chimiques

Country Status (4)

Country Link
EP (1) EP0245477A4 (fr)
JP (1) JPS63501446A (fr)
CA (1) CA1259374A (fr)
WO (1) WO1987003095A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214205B1 (en) 1996-01-26 2001-04-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Determination of an analyte in a liquid medium
WO2010088770A1 (fr) * 2009-02-05 2010-08-12 National Research Council Of Canada Capteur pour mesurer la concentration d'un solvant ou d'un soluté dans un système mixte en solution
US10436772B2 (en) 2014-08-25 2019-10-08 United Arab Emirates University Method and system for counting white blood cells electrically
US10564123B2 (en) 2014-05-25 2020-02-18 United Arab Emirates University Bioreactor system and method of operating same for cellular composition identification and quantification

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001048A (en) * 1987-06-05 1991-03-19 Aurthur D. Little, Inc. Electrical biosensor containing a biological receptor immobilized and stabilized in a protein film
US5192507A (en) * 1987-06-05 1993-03-09 Arthur D. Little, Inc. Receptor-based biosensors
JPS6486053A (en) * 1987-09-29 1989-03-30 Toshiba Corp Sensitive element
GB8804669D0 (en) * 1988-02-27 1988-03-30 Medical Res Council Immobilisation of haptens
US5328847A (en) * 1990-02-20 1994-07-12 Case George D Thin membrane sensor with biochemical switch
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
IL103674A0 (en) * 1991-11-19 1993-04-04 Houston Advanced Res Center Method and apparatus for molecule detection
FI103151B1 (fi) * 1994-03-31 1999-04-30 Elias Hakalehto Immunomääritykseen soveltuva laitteisto ja menetelmä sen käyttämiseksi
GB9607898D0 (en) * 1996-04-17 1996-06-19 British Nuclear Fuels Plc Improvements in and relating to sensors
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
DE19822123C2 (de) * 1997-11-21 2003-02-06 Meinhard Knoll Verfahren und Vorrichtung zum Nachweis von Analyten
US6221673B1 (en) * 1997-11-25 2001-04-24 Microsensor Systems Inc. Materials, method and apparatus for detection and monitoring of chemical species
DE10002595A1 (de) * 2000-01-21 2001-08-09 Infineon Technologies Ag Messverfahren und Sensorvorrichtung für die chemische und pharmazeutische Analytik und Synthese
DE10051252A1 (de) * 2000-10-16 2002-04-25 Caesar Stiftung Bio-Chip
US6797150B2 (en) 2001-10-10 2004-09-28 Lifescan, Inc. Determination of sample volume adequacy in biosensor devices
US6861224B2 (en) 2001-11-02 2005-03-01 Fujitsu Limited Protein detecting device
US6872298B2 (en) * 2001-11-20 2005-03-29 Lifescan, Inc. Determination of sample volume adequacy in biosensor devices
US20040110277A1 (en) * 2002-04-12 2004-06-10 Seiko Epson Corporation Sensor cell, bio-sensor, capacitance element manufacturing method, biological reaction detection method and genetic analytical method
WO2004087946A2 (fr) * 2003-04-02 2004-10-14 Bioscora Gmbh Procede d'identification d'activites de modification post-translationnelles et systemes d'appareils permettant la mise en oeuvre dudit procede
KR100969671B1 (ko) * 2008-03-28 2010-07-14 디지탈 지노믹스(주) 고감도 바이오 센서 및 이를 포함하는 바이오 칩 그리고이를 제조하는 방법
US8571805B2 (en) * 2009-04-10 2013-10-29 Pharmaco-Kinesis Corporation Method and apparatus for detecting and regulating vascular endothelial growth factor (VEGF) by forming a homeostatic loop employing a half-antibody biosensor
US9103773B2 (en) 2010-05-06 2015-08-11 Seoul National University R&D Foundation Capacitive element sensor and method for manufacturing same
GB2531924B (en) * 2013-03-28 2020-04-29 Indian Council Of Agricultural Res A device for detection and analysis of mycotoxins
WO2015083749A1 (fr) * 2013-12-03 2015-06-11 シャープ株式会社 Puce de capteur et système de biocapteur
JP7152708B2 (ja) * 2017-12-14 2022-10-13 島根県 静電容量型センサ
WO2020118052A1 (fr) * 2018-12-05 2020-06-11 FemtoDx Procédés et dispositifs de mesure de capteur différentiel

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2407110C3 (de) * 1974-02-14 1981-04-23 Siemens AG, 1000 Berlin und 8000 München Sensor zum Nachweis einer in einem Gas oder einer Flüssigkeit einthaltenen Substanz
US4238757A (en) * 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
CA1108234A (fr) * 1978-08-02 1981-09-01 George A. Volgyesi Mesure de la concentration des gaz anesthesiques
GB2077437A (en) * 1980-06-07 1981-12-16 Emi Ltd Ammonia gas sensors
US4334880A (en) * 1980-10-20 1982-06-15 Malmros Mark K Analytical device having semiconductive polyacetylene element associated with analyte-binding substance
US4571543A (en) * 1983-03-28 1986-02-18 Southwest Medical Products, Inc. Specific material detection and measuring device
GB8314523D0 (en) * 1983-05-25 1983-06-29 Lowe C R Diagnostic device
GB8406955D0 (en) * 1984-03-16 1984-04-18 Serono Diagnostics Ltd Assay
EP0213825A3 (fr) * 1985-08-22 1989-04-26 Molecular Devices Corporation Capacitance multiple chimiquement modulée

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6214205B1 (en) 1996-01-26 2001-04-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Determination of an analyte in a liquid medium
WO2010088770A1 (fr) * 2009-02-05 2010-08-12 National Research Council Of Canada Capteur pour mesurer la concentration d'un solvant ou d'un soluté dans un système mixte en solution
US8988085B2 (en) 2009-02-05 2015-03-24 National Research Council Of Canada Sensor for measuring the concentration of a solvent or solute in a mixed solution system
US10564123B2 (en) 2014-05-25 2020-02-18 United Arab Emirates University Bioreactor system and method of operating same for cellular composition identification and quantification
US10436772B2 (en) 2014-08-25 2019-10-08 United Arab Emirates University Method and system for counting white blood cells electrically

Also Published As

Publication number Publication date
EP0245477A4 (fr) 1989-08-09
JPS63501446A (ja) 1988-06-02
WO1987003095A1 (fr) 1987-05-21
EP0245477A1 (fr) 1987-11-19

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Legal Events

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