CA1245635A - .alpha.-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF - Google Patents

.alpha.-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF

Info

Publication number
CA1245635A
CA1245635A CA000470937A CA470937A CA1245635A CA 1245635 A CA1245635 A CA 1245635A CA 000470937 A CA000470937 A CA 000470937A CA 470937 A CA470937 A CA 470937A CA 1245635 A CA1245635 A CA 1245635A
Authority
CA
Canada
Prior art keywords
hanp
amino
group
peptide
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000470937A
Other languages
English (en)
French (fr)
Inventor
Hisayuki Matsuo
Kenji Kangawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asubio Pharma Co Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of CA1245635A publication Critical patent/CA1245635A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA000470937A 1983-12-26 1984-12-21 .alpha.-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF Expired CA1245635A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58-243675 1983-12-26
JP58243675A JPS60136596A (ja) 1983-12-26 1983-12-26 ペプチド及びこれを有効成分とする利尿剤

Publications (1)

Publication Number Publication Date
CA1245635A true CA1245635A (en) 1988-11-29

Family

ID=17107313

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000470937A Expired CA1245635A (en) 1983-12-26 1984-12-21 .alpha.-HUMAN ATRIAL NATRIURETIC POLYPEPTIDE AND PHARMACEUTICAL USE THEREOF

Country Status (10)

Country Link
US (2) US5354900A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (2) EP0147193B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS60136596A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE62252T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU578057B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1245635A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3484391D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK170618B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ210750A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA8410044B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116784B1 (en) * 1982-02-22 1992-06-10 Queen's University At Kingston Atrial natriuretic factor
AU572173B2 (en) * 1983-08-29 1988-05-05 Institut De Recherches Cliniques De Montreal Natriuretic factors
JPS60184098A (ja) * 1984-03-02 1985-09-19 Suntory Ltd 新規なペプチド及びこれを有効成分とする利尿剤
AU600652B2 (en) * 1984-06-08 1990-08-23 Hisayuki Matsuo Human atrial natriuretic peptide and gene encoding same
JPH0672155B2 (ja) * 1984-08-24 1994-09-14 塩野義製薬株式会社 α−ｈＡＮＰ抗血清作製用ポリペプチド
JPH0672157B2 (ja) * 1984-08-29 1994-09-14 味の素株式会社 新規ペプチド
DE3443257A1 (de) * 1984-11-28 1986-05-28 Bissendorf Peptide GmbH, 3002 Wedemark Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)
IT1216865B (it) 1987-02-03 1990-03-14 Eniricerche Spa Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.
US5461142A (en) * 1987-11-07 1995-10-24 Pharma Bissendorf Peptide Gmbh Phosphorylated derivatives of cardiodilatin/ANF peptides
US5204327A (en) * 1988-11-18 1993-04-20 Ashi Kasei Kogyo Kabushiki Kaisha Treatment of cerebral edema with anp pharmaceutical compositions
JP3026351B2 (ja) 1990-07-13 2000-03-27 壽之 松尾 ブタｃｎｐ遺伝子及び前駆体蛋白
JP2925391B2 (ja) * 1992-01-09 1999-07-28 サントリー株式会社 Ａｒｄｓ治療用医薬組成物
EP1118329A4 (en) 1998-09-28 2004-12-15 Santen Pharmaceutical Co Ltd LACRYMAL SECRETION PROMOTERS OR OPHTHALMOLOGICAL DROPS CONTAINING NATRIURETIC PEPTIDES AS ACTIVE INGREDIENTS FOR TREATING KERATOCONJUNCTIVITY
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
US7601691B2 (en) * 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US20040266673A1 (en) * 2002-07-31 2004-12-30 Peter Bakis Long lasting natriuretic peptide derivatives
JP2003530847A (ja) 2000-04-12 2003-10-21 ヒューマン ゲノム サイエンシズ インコーポレイテッド アルブミン融合タンパク質
IL145926A0 (en) * 2001-10-15 2002-07-25 Mor Research Applic Ltd Peptide epitopes of mimotopes useful in immunomodulation
US20080194481A1 (en) * 2001-12-21 2008-08-14 Human Genome Sciences, Inc. Albumin Fusion Proteins
US20060233863A1 (en) 2003-02-10 2006-10-19 Enzymotec Ltd. Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
IL155136A0 (en) * 2003-02-10 2003-10-31 Enzymotec Ltd A composition for reducing blood cholesterol and triglycerides
EP1776159A1 (en) * 2004-08-09 2007-04-25 Enzymotec Ltd. Food products for diabetics
AU2005270831B2 (en) 2004-08-10 2011-08-25 Enzymotec Ltd. Mixture of phytosterol ester(s) and 1, 3-diglyceride(s) for use in the treatment of medical conditions
WO2007000768A2 (en) * 2005-06-28 2007-01-04 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Gliomedin, fragments thereof and methods of using same
CA2654055A1 (en) 2006-06-07 2007-12-21 Human Genome Sciences, Inc. Albumin fusion proteins
US20090099074A1 (en) * 2007-01-10 2009-04-16 Conjuchem Biotechnologies Inc. Modulating food intake
US20100150924A1 (en) * 2007-05-22 2010-06-17 Elior Peles Regulation of myelination by nectin-like (necl) molecules

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116784B1 (en) * 1982-02-22 1992-06-10 Queen's University At Kingston Atrial natriuretic factor
ZA846084B (en) * 1983-08-29 1985-05-29 Montreal Inst Rech Cliniques Natriuretic factors
AU572173B2 (en) * 1983-08-29 1988-05-05 Institut De Recherches Cliniques De Montreal Natriuretic factors
US4496544A (en) * 1983-11-10 1985-01-29 Washington University Atrial Peptides
DE3346953A1 (de) * 1983-12-24 1985-08-14 Organogen Medizinisch-Molekularbiologische Forschungsgesellschaft mbH, 6900 Heidelberg Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung
US4508712A (en) * 1984-01-10 1985-04-02 Washington University Atrial peptide
JPS60184098A (ja) * 1984-03-02 1985-09-19 Suntory Ltd 新規なペプチド及びこれを有効成分とする利尿剤
WO1985004872A1 (en) * 1984-04-24 1985-11-07 The Salk Institute For Biological Studies Atrial peptide analogs
DE3443257A1 (de) * 1984-11-28 1986-05-28 Bissendorf Peptide GmbH, 3002 Wedemark Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)

Also Published As

Publication number Publication date
ZA8410044B (en) 1985-08-28
NZ210750A (en) 1991-05-28
EP0398451A1 (en) 1990-11-22
AU3713384A (en) 1985-07-04
US5354900A (en) 1994-10-11
JPS60136596A (ja) 1985-07-20
AU578057B2 (en) 1988-10-13
EP0147193B1 (en) 1991-04-03
EP0147193A3 (en) 1987-08-12
DK624884A (da) 1985-06-27
DK624884D0 (da) 1984-12-21
DE3484391D1 (de) 1991-05-08
EP0147193A2 (en) 1985-07-03
US4748232A (en) 1988-05-31
DK170618B1 (da) 1995-11-13
JPS6319520B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-04-22
ATE62252T1 (de) 1991-04-15

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Legal Events

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