IT1216865B - Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. - Google Patents
Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.Info
- Publication number
- IT1216865B IT1216865B IT8719234A IT1923487A IT1216865B IT 1216865 B IT1216865 B IT 1216865B IT 8719234 A IT8719234 A IT 8719234A IT 1923487 A IT1923487 A IT 1923487A IT 1216865 B IT1216865 B IT 1216865B
- Authority
- IT
- Italy
- Prior art keywords
- derivative
- argininic
- peptidal
- synthesis
- procedure
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- 239000004475 Arginine Substances 0.000 abstract 2
- 125000003088 (fluoren-9-ylmethoxy)carbonyl group Chemical group 0.000 abstract 1
- 150000001483 arginine derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D249/18—Benzotriazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8719234A IT1216865B (it) | 1987-02-03 | 1987-02-03 | Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. |
| EP88100919A EP0277561B1 (en) | 1987-02-03 | 1988-01-22 | New arginine derivative, process for the preparation thereof and its use in peptide synthesis |
| AT88100919T ATE74905T1 (de) | 1987-02-03 | 1988-01-22 | Argininderivat, verfahren zu seiner herstellung und seine verwendung in der peptidsynthese. |
| DE8888100919T DE3869979D1 (de) | 1987-02-03 | 1988-01-22 | Argininderivat, verfahren zu seiner herstellung und seine verwendung in der peptidsynthese. |
| CA000557377A CA1327868C (en) | 1987-02-03 | 1988-01-26 | Arginine derivative, process for the preparation thereof and its use in peptide synthesis |
| JP63021431A JPH01197465A (ja) | 1987-02-03 | 1988-02-02 | 新規アルギニン誘導体、その製法及びペプチド合成における使用法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8719234A IT1216865B (it) | 1987-02-03 | 1987-02-03 | Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8719234A0 IT8719234A0 (it) | 1987-02-03 |
| IT1216865B true IT1216865B (it) | 1990-03-14 |
Family
ID=11155987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8719234A IT1216865B (it) | 1987-02-03 | 1987-02-03 | Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0277561B1 (it) |
| JP (1) | JPH01197465A (it) |
| AT (1) | ATE74905T1 (it) |
| CA (1) | CA1327868C (it) |
| DE (1) | DE3869979D1 (it) |
| IT (1) | IT1216865B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1227906B (it) * | 1988-12-23 | 1991-05-14 | Eniricerche S P A Milano Sclav | Nuovo procedimento per la sintesi della n alfa -fluorenilmetossicar bonil-n(elevato a g)- tritil-arginina |
| US5710324A (en) * | 1990-02-26 | 1998-01-20 | Merrell Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
| AU636713B2 (en) * | 1990-02-26 | 1993-05-06 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
| US5318992A (en) * | 1990-02-26 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB791319A (en) * | 1954-08-18 | 1958-02-26 | Roussel Uclaf | Process for the production of peptides |
| US3835175A (en) * | 1971-03-15 | 1974-09-10 | Research Corp | 9-fluorenylmethanol haloformates, carbonates and thiocarbonates |
| US4108846A (en) * | 1977-02-01 | 1978-08-22 | Hoffmann-La Roche Inc. | Solid phase synthesis with base N alpha-protecting group cleavage |
| US4309340A (en) | 1980-03-31 | 1982-01-05 | American Home Products Corporation | Polypeptide compositions |
| US4305852A (en) | 1980-10-20 | 1981-12-15 | American Home Products Corporation | Polypeptide compositions |
| US4477428A (en) * | 1982-08-26 | 1984-10-16 | Johnson & Johnson Products, Inc. | Oral compositions comprising N.sup.α,NG -diacyl derivatives of arginine |
| US4499068A (en) * | 1982-08-26 | 1985-02-12 | Johnson & Johnson Products, Inc. | Oral compositions comprising NG -alkyl derivatives of arginine |
| JPS6061557A (ja) * | 1983-09-14 | 1985-04-09 | Nitto Boseki Co Ltd | アルギニル−p−ニトロアニリド化合物の製造方法 |
| US4496544A (en) | 1983-11-10 | 1985-01-29 | Washington University | Atrial Peptides |
| JPS60136596A (ja) | 1983-12-26 | 1985-07-20 | Suntory Ltd | ペプチド及びこれを有効成分とする利尿剤 |
| ATE120759T1 (de) | 1984-04-19 | 1995-04-15 | Scios Nova Inc | Atrielle natriumuretische/gefässerweiterende polypeptide. |
-
1987
- 1987-02-03 IT IT8719234A patent/IT1216865B/it active
-
1988
- 1988-01-22 EP EP88100919A patent/EP0277561B1/en not_active Expired - Lifetime
- 1988-01-22 DE DE8888100919T patent/DE3869979D1/de not_active Expired - Lifetime
- 1988-01-22 AT AT88100919T patent/ATE74905T1/de not_active IP Right Cessation
- 1988-01-26 CA CA000557377A patent/CA1327868C/en not_active Expired - Fee Related
- 1988-02-02 JP JP63021431A patent/JPH01197465A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IT8719234A0 (it) | 1987-02-03 |
| DE3869979D1 (de) | 1992-05-21 |
| ATE74905T1 (de) | 1992-05-15 |
| EP0277561B1 (en) | 1992-04-15 |
| EP0277561A1 (en) | 1988-08-10 |
| JPH01197465A (ja) | 1989-08-09 |
| CA1327868C (en) | 1994-03-15 |
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