IT1216865B - Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. - Google Patents

Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.

Info

Publication number
IT1216865B
IT1216865B IT8719234A IT1923487A IT1216865B IT 1216865 B IT1216865 B IT 1216865B IT 8719234 A IT8719234 A IT 8719234A IT 1923487 A IT1923487 A IT 1923487A IT 1216865 B IT1216865 B IT 1216865B
Authority
IT
Italy
Prior art keywords
derivative
argininic
peptidal
synthesis
procedure
Prior art date
Application number
IT8719234A
Other languages
English (en)
Other versions
IT8719234A0 (it
Inventor
Valerio Caciagli
Antonio Silvio Verdini
Original Assignee
Eniricerche Spa
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa, Sclavo Spa filed Critical Eniricerche Spa
Priority to IT8719234A priority Critical patent/IT1216865B/it
Publication of IT8719234A0 publication Critical patent/IT8719234A0/it
Priority to EP88100919A priority patent/EP0277561B1/en
Priority to AT88100919T priority patent/ATE74905T1/de
Priority to DE8888100919T priority patent/DE3869979D1/de
Priority to CA000557377A priority patent/CA1327868C/en
Priority to JP63021431A priority patent/JPH01197465A/ja
Application granted granted Critical
Publication of IT1216865B publication Critical patent/IT1216865B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18Benzotriazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8719234A 1987-02-03 1987-02-03 Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche. IT1216865B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT8719234A IT1216865B (it) 1987-02-03 1987-02-03 Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.
EP88100919A EP0277561B1 (en) 1987-02-03 1988-01-22 New arginine derivative, process for the preparation thereof and its use in peptide synthesis
AT88100919T ATE74905T1 (de) 1987-02-03 1988-01-22 Argininderivat, verfahren zu seiner herstellung und seine verwendung in der peptidsynthese.
DE8888100919T DE3869979D1 (de) 1987-02-03 1988-01-22 Argininderivat, verfahren zu seiner herstellung und seine verwendung in der peptidsynthese.
CA000557377A CA1327868C (en) 1987-02-03 1988-01-26 Arginine derivative, process for the preparation thereof and its use in peptide synthesis
JP63021431A JPH01197465A (ja) 1987-02-03 1988-02-02 新規アルギニン誘導体、その製法及びペプチド合成における使用法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8719234A IT1216865B (it) 1987-02-03 1987-02-03 Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.

Publications (2)

Publication Number Publication Date
IT8719234A0 IT8719234A0 (it) 1987-02-03
IT1216865B true IT1216865B (it) 1990-03-14

Family

ID=11155987

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8719234A IT1216865B (it) 1987-02-03 1987-02-03 Derivato argininico, procedimento per la sua preparazione e suo impiego nelle sintesi peptidiche.

Country Status (6)

Country Link
EP (1) EP0277561B1 (it)
JP (1) JPH01197465A (it)
AT (1) ATE74905T1 (it)
CA (1) CA1327868C (it)
DE (1) DE3869979D1 (it)
IT (1) IT1216865B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1227906B (it) * 1988-12-23 1991-05-14 Eniricerche S P A Milano Sclav Nuovo procedimento per la sintesi della n alfa -fluorenilmetossicar bonil-n(elevato a g)- tritil-arginina
US5710324A (en) * 1990-02-26 1998-01-20 Merrell Pharmaceuticals Inc. Inhibitors of nitric oxide biosynthesis
AU636713B2 (en) * 1990-02-26 1993-05-06 Merrell Dow Pharmaceuticals Inc. Inhibitors of nitric oxide biosynthesis
US5318992A (en) * 1990-02-26 1994-06-07 Merrell Dow Pharmaceuticals Inc. Inhibitors of nitric oxide biosynthesis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB791319A (en) * 1954-08-18 1958-02-26 Roussel Uclaf Process for the production of peptides
US3835175A (en) * 1971-03-15 1974-09-10 Research Corp 9-fluorenylmethanol haloformates, carbonates and thiocarbonates
US4108846A (en) * 1977-02-01 1978-08-22 Hoffmann-La Roche Inc. Solid phase synthesis with base N alpha-protecting group cleavage
US4309340A (en) 1980-03-31 1982-01-05 American Home Products Corporation Polypeptide compositions
US4305852A (en) 1980-10-20 1981-12-15 American Home Products Corporation Polypeptide compositions
US4477428A (en) * 1982-08-26 1984-10-16 Johnson & Johnson Products, Inc. Oral compositions comprising N.sup.α,NG -diacyl derivatives of arginine
US4499068A (en) * 1982-08-26 1985-02-12 Johnson & Johnson Products, Inc. Oral compositions comprising NG -alkyl derivatives of arginine
JPS6061557A (ja) * 1983-09-14 1985-04-09 Nitto Boseki Co Ltd アルギニル−p−ニトロアニリド化合物の製造方法
US4496544A (en) 1983-11-10 1985-01-29 Washington University Atrial Peptides
JPS60136596A (ja) 1983-12-26 1985-07-20 Suntory Ltd ペプチド及びこれを有効成分とする利尿剤
ATE120759T1 (de) 1984-04-19 1995-04-15 Scios Nova Inc Atrielle natriumuretische/gefässerweiterende polypeptide.

Also Published As

Publication number Publication date
IT8719234A0 (it) 1987-02-03
DE3869979D1 (de) 1992-05-21
ATE74905T1 (de) 1992-05-15
EP0277561B1 (en) 1992-04-15
EP0277561A1 (en) 1988-08-10
JPH01197465A (ja) 1989-08-09
CA1327868C (en) 1994-03-15

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