CA1244009A - Lh-rh antagonists - Google Patents

Lh-rh antagonists

Info

Publication number
CA1244009A
CA1244009A CA000460953A CA460953A CA1244009A CA 1244009 A CA1244009 A CA 1244009A CA 000460953 A CA000460953 A CA 000460953A CA 460953 A CA460953 A CA 460953A CA 1244009 A CA1244009 A CA 1244009A
Authority
CA
Canada
Prior art keywords
arg
group
alanyl
phe
bal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000460953A
Other languages
English (en)
French (fr)
Inventor
Hubert J.J. Loozen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of CA1244009A publication Critical patent/CA1244009A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA000460953A 1983-08-16 1984-08-14 Lh-rh antagonists Expired CA1244009A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL8302875 1983-08-16
NL83.02875 1983-08-16
NL8400153 1984-01-18
NL84.00153 1984-01-18

Publications (1)

Publication Number Publication Date
CA1244009A true CA1244009A (en) 1988-11-01

Family

ID=26645882

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000460953A Expired CA1244009A (en) 1983-08-16 1984-08-14 Lh-rh antagonists

Country Status (13)

Country Link
US (1) US4628044A (fi)
EP (1) EP0145032B1 (fi)
KR (1) KR920004824B1 (fi)
AU (1) AU566672B2 (fi)
CA (1) CA1244009A (fi)
DE (1) DE3467173D1 (fi)
DK (1) DK164109C (fi)
ES (1) ES8602617A1 (fi)
FI (1) FI89174C (fi)
GR (1) GR80108B (fi)
HU (1) HU200481B (fi)
IE (1) IE57717B1 (fi)
PT (1) PT79074B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
US4690916A (en) * 1984-11-13 1987-09-01 Syntex (U.S.A.) Inc. Nona and decapeptide analogs of LHRH useful as LHRH antagonists
US4661472A (en) * 1985-05-09 1987-04-28 The Salk Institute For Biological Studies GnRH antagonists IX
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
DE3634435A1 (de) * 1986-10-09 1988-04-14 Hoechst Ag Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
US4801577A (en) * 1987-02-05 1989-01-31 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists
US5064939A (en) * 1990-02-06 1991-11-12 The Salk Institute For Biological Studies Cyclic gnrh antagonists
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung
EP2662087A1 (en) 2003-04-22 2013-11-13 Ipsen Pharma Somatostatin vectors
JP5926876B2 (ja) * 2013-12-25 2016-05-25 本田技研工業株式会社 潤滑油の熱交換装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041286B1 (en) * 1980-06-02 1984-08-15 Andrew Victor Schally Lh-rh antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
FI832053L (fi) * 1982-06-10 1983-12-11 Syntex Inc Nonapeptid- och dekapeptidanaloger av lhrh anvaendbara som lhrh-antagonister samt deras framstaellningsfoerfarande
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II

Also Published As

Publication number Publication date
AU566672B2 (en) 1987-10-29
KR920004824B1 (ko) 1992-06-18
DK392284A (da) 1985-02-17
FI843221A (fi) 1985-02-17
IE57717B1 (en) 1993-03-10
DK164109B (da) 1992-05-11
DE3467173D1 (en) 1987-12-10
US4628044A (en) 1986-12-09
AU3174784A (en) 1985-02-21
IE842031L (en) 1985-02-16
EP0145032A1 (en) 1985-06-19
FI843221A0 (fi) 1984-08-15
PT79074A (en) 1984-09-01
HU200481B (en) 1990-06-28
FI89174B (fi) 1993-05-14
DK392284D0 (da) 1984-08-15
ES535120A0 (es) 1985-12-01
EP0145032B1 (en) 1987-11-04
DK164109C (da) 1992-10-12
PT79074B (en) 1986-08-14
GR80108B (en) 1984-12-14
FI89174C (fi) 1993-08-25
ES8602617A1 (es) 1985-12-01
HUT34766A (en) 1985-04-28
KR850001774A (ko) 1985-04-01

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Legal Events

Date Code Title Description
MKEX Expiry