CA1223253A - Process for the preparation of (8s)-8- fluoroerythromycins - Google Patents

Process for the preparation of (8s)-8- fluoroerythromycins

Info

Publication number
CA1223253A
CA1223253A CA000458987A CA458987A CA1223253A CA 1223253 A CA1223253 A CA 1223253A CA 000458987 A CA000458987 A CA 000458987A CA 458987 A CA458987 A CA 458987A CA 1223253 A CA1223253 A CA 1223253A
Authority
CA
Canada
Prior art keywords
fluoroerythromycin
hemiketal
fluorination
anhydroerythromycin
perchloryl fluoride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000458987A
Other languages
English (en)
French (fr)
Inventor
Luciano Toscano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pierrel SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel SpA filed Critical Pierrel SpA
Application granted granted Critical
Publication of CA1223253A publication Critical patent/CA1223253A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CA000458987A 1983-07-18 1984-07-16 Process for the preparation of (8s)-8- fluoroerythromycins Expired CA1223253A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22104/83A IT1163796B (it) 1983-07-18 1983-07-18 Procedimento per la preparazione di (8s)-8-fluoroeritromicina
IT22104A/83 1983-07-18

Publications (1)

Publication Number Publication Date
CA1223253A true CA1223253A (en) 1987-06-23

Family

ID=11191551

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000458987A Expired CA1223253A (en) 1983-07-18 1984-07-16 Process for the preparation of (8s)-8- fluoroerythromycins

Country Status (10)

Country Link
US (1) US4673736A (Direct)
EP (1) EP0135207B1 (Direct)
JP (1) JPS6038394A (Direct)
KR (1) KR910008110B1 (Direct)
AT (1) ATE40893T1 (Direct)
CA (1) CA1223253A (Direct)
DE (1) DE3476804D1 (Direct)
FI (1) FI74288C (Direct)
IT (1) IT1163796B (Direct)
PH (1) PH21033A (Direct)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175150A (en) * 1985-08-31 1992-12-29 Kitasato, Kenkyusho Erythromycin derivative
US4876245A (en) * 1986-12-22 1989-10-24 Daikin Industries Ltd. Fluorine-containing macrolide compounds and their use
US5393743A (en) * 1993-07-06 1995-02-28 Abbott Laboratories Erythromycin derivatives
US5552533A (en) * 1994-09-14 1996-09-03 Alliedsignal Inc. Preparation of (8S)-8-fluoroerythromycins with N-F fluorinating agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0056291B1 (en) * 1981-01-09 1986-01-08 Pierrel S.p.A. Novel semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
IT1195299B (it) * 1981-11-27 1988-10-12 Pierrel Spa Procedimento chimico di sintesi per la preparazione di antibiotici macrolidici

Also Published As

Publication number Publication date
US4673736A (en) 1987-06-16
FI842894A0 (fi) 1984-07-18
IT8322104A1 (it) 1985-01-18
FI74288C (fi) 1988-01-11
JPS6038394A (ja) 1985-02-27
KR850001228A (ko) 1985-03-16
EP0135207B1 (en) 1989-02-22
FI74288B (fi) 1987-09-30
EP0135207A1 (en) 1985-03-27
FI842894A7 (fi) 1985-01-19
DE3476804D1 (en) 1989-03-30
IT1163796B (it) 1987-04-08
ATE40893T1 (de) 1989-03-15
KR910008110B1 (ko) 1991-10-10
PH21033A (en) 1987-06-30
IT8322104A0 (it) 1983-07-18
JPH0566396B2 (Direct) 1993-09-21

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Legal Events

Date Code Title Description
MKEX Expiry