CA1202893A - Stable radioactive diagnostic agent and a non- radioactive carrier therefor - Google Patents
Stable radioactive diagnostic agent and a non- radioactive carrier thereforInfo
- Publication number
- CA1202893A CA1202893A CA000416825A CA416825A CA1202893A CA 1202893 A CA1202893 A CA 1202893A CA 000416825 A CA000416825 A CA 000416825A CA 416825 A CA416825 A CA 416825A CA 1202893 A CA1202893 A CA 1202893A
- Authority
- CA
- Canada
- Prior art keywords
- 99mtc
- radioactive
- agent
- water
- plmt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 229910052713 technetium Inorganic materials 0.000 description 1
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 description 1
- CVKJXWOUXWRRJT-UHFFFAOYSA-N technetium dioxide Chemical compound O=[Tc]=O CVKJXWOUXWRRJT-UHFFFAOYSA-N 0.000 description 1
- AXZWODMDQAVCJE-UHFFFAOYSA-L tin(II) chloride (anhydrous) Chemical compound [Cl-].[Cl-].[Sn+2] AXZWODMDQAVCJE-UHFFFAOYSA-L 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- High Energy & Nuclear Physics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56195215A JPS5896031A (ja) | 1981-12-03 | 1981-12-03 | 放射性診断剤およびその製造用組成物 |
| JP195215/1981 | 1981-12-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1202893A true CA1202893A (en) | 1986-04-08 |
Family
ID=16337372
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000416825A Expired CA1202893A (en) | 1981-12-03 | 1982-12-02 | Stable radioactive diagnostic agent and a non- radioactive carrier therefor |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4489053A (ko) |
| EP (1) | EP0081193B1 (ko) |
| JP (1) | JPS5896031A (ko) |
| KR (1) | KR860000687B1 (ko) |
| AU (1) | AU532748B2 (ko) |
| CA (1) | CA1202893A (ko) |
| DE (1) | DE3270032D1 (ko) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4510125A (en) * | 1982-12-08 | 1985-04-09 | Mallinckrodt, Inc. | Process for making lyophilized radiographic imaging kit |
| EP0111414A3 (en) * | 1982-12-08 | 1985-05-02 | Mallinckrodt, Inc. (a Delaware corporation) | Radiographic imaging agents |
| US4707353A (en) * | 1982-12-08 | 1987-11-17 | Mallinckrodt, Inc. | Radiographic imaging agents |
| JPS59199636A (ja) * | 1983-04-26 | 1984-11-12 | Nippon Mejifuijitsukusu Kk | 放射性診断剤 |
| US4942231A (en) * | 1984-05-24 | 1990-07-17 | Mallinckrodt, Inc. | Method of preparing a chlorinated, brominated, radio-brominated, iodinated and/or radioiodinated aromatic or heteroaromatic compound |
| US4992555A (en) * | 1987-05-08 | 1991-02-12 | Salutar, Inc. | Certain dipyridylphosphate chelatable compounds capable of forming metal ion chelates |
| US5130431A (en) * | 1987-05-08 | 1992-07-14 | Salutar, Inc. | Dipyriodoxyl phosphate chelating compound intermediates |
| US5091169A (en) * | 1987-05-08 | 1992-02-25 | Salutar, Inc. | Dipyridoxyl phosphate NMRI contrast agent compositions |
| AR246956A1 (es) | 1987-05-08 | 1994-10-31 | Salutar Inc | Compuesto quelante, un intermediario para preparar el mismo, y un procedimiento para preparar una composicion de medio de contraste. |
| US4992554A (en) * | 1987-05-08 | 1991-02-12 | Salutar, Inc. | Dipyridoxyl phosphate chelating compounds |
| US4880615A (en) * | 1988-11-25 | 1989-11-14 | Merck & Co., Inc. | Stabilized radiopharmaceutical compositions |
| GB8902362D0 (en) * | 1989-02-03 | 1989-03-22 | Amersham Int Plc | Cationic complexes of technetium-99m |
| US5219556A (en) * | 1990-07-09 | 1993-06-15 | Mallinckrodt Medical, Inc. | Stabilized therapeutic radiopharmaceutical complexes |
| JP2860157B2 (ja) * | 1990-10-31 | 1999-02-24 | 日本メジフィジックス株式会社 | 腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法 |
| WO1995033757A1 (en) * | 1994-06-03 | 1995-12-14 | Mallinckrodt Medical, Inc. | RAPIDLY CLEARING TECHNETIUM-99m PHOSPHONATE SKELETAL IMAGING AGENTS |
| CN1063344C (zh) * | 1995-07-27 | 2001-03-21 | 北京市肿瘤防治研究所 | 一种肿瘤阳性显像剂锝-99m标记平阳霉素用药盒 |
| US6027710A (en) * | 1996-09-18 | 2000-02-22 | Nihon Medi-Physiscs Co., Ltd. | Radiation-protecting agent |
| WO2006085941A1 (en) * | 2004-06-17 | 2006-08-17 | Anazaohealth Corporation | Copper-complex isonitrile positron emission tomography (pet) imaging agent and method |
| US7229603B2 (en) * | 2004-06-17 | 2007-06-12 | Anazaohealth Corporation | Stablilized and lyophilized radiopharmaceutical agents |
| GB0427392D0 (en) * | 2004-12-15 | 2005-01-19 | Amersham Plc | Stabilised 99mTc compositions |
| US9321095B2 (en) | 2010-06-30 | 2016-04-26 | General Electric Company | Apparatuses and methods for cutting porous substrates |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU485693B2 (en) * | 1973-08-24 | 1976-02-05 | The Council Ofthe Institute Of Medical And Veterinary Science, Andthe Universityof Adelaide Gariti Cancer Foundation | New radiopharmaceuticals for cholescintigraphy |
| ZA761944B (en) * | 1975-04-30 | 1977-03-30 | Procter & Gamble | Stable radiographic scanning agents |
| US4364920A (en) * | 1975-04-30 | 1982-12-21 | Medi-Physics, Inc. | Stable diagnostic reagents |
| US4233284A (en) * | 1978-03-31 | 1980-11-11 | The Procter & Gamble Company | Stabilized radiographic scanning agents |
| US4232000A (en) * | 1978-06-28 | 1980-11-04 | The Procter & Gamble Company | Radioactive scanning agents with stabilizer |
| US4229427A (en) * | 1978-06-28 | 1980-10-21 | The Procter & Gamble Company | Radioactive scanning agents with hydroquinone stabilizer |
| US4247534A (en) * | 1978-07-31 | 1981-01-27 | The Procter & Gamble Company | Radiographic scanning agent |
| JPS5750928A (en) * | 1980-09-13 | 1982-03-25 | Nippon Mejifuijitsukusu Kk | Diagnostic agent for scanning bone |
| JP2627291B2 (ja) * | 1987-02-20 | 1997-07-02 | 武田薬品工業株式会社 | 安定化された殺虫・殺菌農薬組成物 |
-
1981
- 1981-12-03 JP JP56195215A patent/JPS5896031A/ja active Granted
-
1982
- 1982-12-01 DE DE8282111099T patent/DE3270032D1/de not_active Expired
- 1982-12-01 AU AU91034/82A patent/AU532748B2/en not_active Expired
- 1982-12-01 EP EP82111099A patent/EP0081193B1/en not_active Expired
- 1982-12-02 KR KR8205405A patent/KR860000687B1/ko active
- 1982-12-02 CA CA000416825A patent/CA1202893A/en not_active Expired
- 1982-12-02 US US06/446,125 patent/US4489053A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU532748B2 (en) | 1983-10-13 |
| EP0081193A3 (en) | 1984-03-07 |
| JPH0233019B2 (ko) | 1990-07-25 |
| KR860000687B1 (ko) | 1986-06-07 |
| EP0081193A2 (en) | 1983-06-15 |
| AU9103482A (en) | 1983-06-09 |
| DE3270032D1 (en) | 1986-04-24 |
| JPS5896031A (ja) | 1983-06-07 |
| US4489053A (en) | 1984-12-18 |
| EP0081193B1 (en) | 1986-03-19 |
| KR840002645A (ko) | 1984-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |