CA1162544A - Naphthyridine derivatives - Google Patents

Naphthyridine derivatives

Info

Publication number
CA1162544A
CA1162544A CA000390531A CA390531A CA1162544A CA 1162544 A CA1162544 A CA 1162544A CA 000390531 A CA000390531 A CA 000390531A CA 390531 A CA390531 A CA 390531A CA 1162544 A CA1162544 A CA 1162544A
Authority
CA
Canada
Prior art keywords
naphthyridine
acid addition
alkyl
acceptable acid
hexahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000390531A
Other languages
English (en)
French (fr)
Inventor
Regis Dupont
Jonathan Frost
Patrick Lardenois
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of CA1162544A publication Critical patent/CA1162544A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • X-Ray Techniques (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Secondary Cells (AREA)
  • Electrolytic Production Of Metals (AREA)
CA000390531A 1980-11-21 1981-11-20 Naphthyridine derivatives Expired CA1162544A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8024717 1980-11-21
FR8024717A FR2494693A1 (fr) 1980-11-21 1980-11-21 Derives de l'hexahydro-2,3,3a,4,5,6 1h-indolo(3,2,1-de)(naphtyridine-1,5), leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
CA1162544A true CA1162544A (en) 1984-02-21

Family

ID=9248208

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000390531A Expired CA1162544A (en) 1980-11-21 1981-11-20 Naphthyridine derivatives

Country Status (22)

Country Link
JP (1) JPS57116070A (sv)
AT (1) AT379594B (sv)
AU (1) AU546924B2 (sv)
BE (1) BE891204A (sv)
CA (1) CA1162544A (sv)
CH (1) CH649549A5 (sv)
DE (1) DE3143179A1 (sv)
DK (1) DK515681A (sv)
ES (1) ES507317A0 (sv)
FR (1) FR2494693A1 (sv)
GB (1) GB2087889B (sv)
GR (1) GR78026B (sv)
IE (1) IE52160B1 (sv)
IL (1) IL64328A (sv)
IT (1) IT1195292B (sv)
LU (1) LU83775A1 (sv)
NL (1) NL8105282A (sv)
NO (1) NO813945L (sv)
NZ (1) NZ199008A (sv)
PT (1) PT74019B (sv)
SE (1) SE8106918L (sv)
ZA (1) ZA818082B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2527210A1 (fr) * 1982-05-18 1983-11-25 Synthelabo Enantiomeres d'hexahydro-2,3,3a,4,5,6 1h-indolo(3,2,1-de) (naphtyridine-1,5), leur procede de separation et leur application en therapeutique
JPH02180885A (ja) * 1988-09-01 1990-07-13 Glaxo Group Ltd ラクタム誘導体
CN113214250B (zh) * 2021-04-28 2022-06-14 华南理工大学 一种稠合六氢-1,6-萘啶类化合物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD129791A5 (de) * 1976-04-13 1978-02-08 Synthelabo Verfahren zur herstellung von naphtyridinderivaten
GB1550496A (en) * 1976-12-31 1979-08-15 Logeais Labor Jacques 1,2,3,3a4,5-hexahydro-canthine derivatives a process for their preparation and their therapeutic applications

Also Published As

Publication number Publication date
NO813945L (no) 1982-05-24
FR2494693A1 (fr) 1982-05-28
NZ199008A (en) 1984-07-31
IL64328A0 (en) 1982-02-28
IT8125212A0 (it) 1981-11-20
BE891204A (fr) 1982-05-21
PT74019A (fr) 1981-12-01
JPS57116070A (en) 1982-07-19
DK515681A (da) 1982-05-22
AT379594B (de) 1986-01-27
IE52160B1 (en) 1987-07-22
GB2087889A (en) 1982-06-03
ES8207176A1 (es) 1982-09-01
IE812722L (en) 1982-05-21
FR2494693B1 (sv) 1983-03-04
NL8105282A (nl) 1982-06-16
AU7770081A (en) 1982-05-27
GR78026B (sv) 1984-09-26
ZA818082B (en) 1982-10-27
DE3143179A1 (de) 1982-06-24
IL64328A (en) 1985-02-28
LU83775A1 (fr) 1983-09-01
ATA501381A (de) 1985-06-15
GB2087889B (en) 1984-01-25
CH649549A5 (fr) 1985-05-31
AU546924B2 (en) 1985-09-26
SE8106918L (sv) 1982-05-22
PT74019B (fr) 1983-12-07
IT1195292B (it) 1988-10-12
ES507317A0 (es) 1982-09-01

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Legal Events

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