CA1157776A - Directly compressible acetaminophen granulation - Google Patents
Directly compressible acetaminophen granulationInfo
- Publication number
- CA1157776A CA1157776A CA000392780A CA392780A CA1157776A CA 1157776 A CA1157776 A CA 1157776A CA 000392780 A CA000392780 A CA 000392780A CA 392780 A CA392780 A CA 392780A CA 1157776 A CA1157776 A CA 1157776A
- Authority
- CA
- Canada
- Prior art keywords
- acetaminophen
- granulation
- weight
- lubricant
- nacmc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21929080A | 1980-12-22 | 1980-12-22 | |
US219,290 | 1988-07-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1157776A true CA1157776A (en) | 1983-11-29 |
Family
ID=22818680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA000392780A Expired CA1157776A (en) | 1980-12-22 | 1981-12-21 | Directly compressible acetaminophen granulation |
Country Status (10)
Country | Link |
---|---|
JP (1) | JPS57130913A (ja) |
AR (1) | AR226763A1 (ja) |
AU (1) | AU545475B2 (ja) |
BE (1) | BE891557A (ja) |
CA (1) | CA1157776A (ja) |
DE (1) | DE3150557A1 (ja) |
FR (1) | FR2496461B1 (ja) |
GB (1) | GB2090739B (ja) |
MY (1) | MY8600144A (ja) |
PH (1) | PH18488A (ja) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4600579A (en) * | 1983-06-07 | 1986-07-15 | Mallinckrodt, Inc. | N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same |
US4661521A (en) * | 1984-04-30 | 1987-04-28 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
JPS61145111A (ja) * | 1984-12-20 | 1986-07-02 | Lion Corp | アセトアミノフェン含有錠剤の製造方法 |
US4757090A (en) * | 1986-07-14 | 1988-07-12 | Mallinckrodt, Inc. | Direct tableting acetaminophen compositions |
DE3636209A1 (de) * | 1986-10-24 | 1988-04-28 | Lentia Gmbh | Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates |
ES2058288T3 (es) * | 1987-07-08 | 1994-11-01 | American Home Prod | Composiciones de ibuprofen secadas por atomizacion. |
DE3830749A1 (de) * | 1987-09-11 | 1989-03-30 | Squibb & Sons Inc | Arzneimittel in form von kuegelchen mit hohem arzneistoffgehalt und verfahren zu ihrer herstellung |
FR2638971B1 (fr) * | 1988-11-15 | 1993-01-08 | Vacher Dominique | Comprime a delitement et/ou dissolution instantane |
FR2672212B1 (fr) * | 1991-02-04 | 1993-05-28 | Lille Ii Universite | Cristaux de paracetamol pour compression directe, procede de preparation de ces cristaux et comprime obtenu avec ces cristaux. |
JPH0656659A (ja) * | 1992-06-10 | 1994-03-01 | Natl Sci Council | 直接打錠できる薬学組成物及びその錠剤の製造法 |
DE4327462A1 (de) * | 1993-08-16 | 1995-02-23 | Carl Heinrich Dr Weischer | Neue N-Acetyl-p-Aminophenol-Derivate zur Bekämpfung von Schmerzzuständen |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1390032A (en) * | 1971-08-27 | 1975-04-09 | Sterling Winthrop Group Ltd | Pharmaceutical compositions |
JPS535725B2 (ja) * | 1973-03-05 | 1978-03-01 | ||
US3873694A (en) * | 1973-09-27 | 1975-03-25 | Cpc International Inc | Direct compression tabletting composition and pharmaceutical tablets produced therefrom |
US4097606A (en) * | 1975-10-08 | 1978-06-27 | Bristol-Myers Company | APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same |
JPS5344618A (en) * | 1976-10-04 | 1978-04-21 | Takeda Chem Ind Ltd | Preparation of tablet |
DE2713197A1 (de) * | 1977-03-25 | 1978-10-05 | Bayer Ag | Neues paracetamol-granulat |
-
1981
- 1981-12-18 AR AR287856A patent/AR226763A1/es active
- 1981-12-21 CA CA000392780A patent/CA1157776A/en not_active Expired
- 1981-12-21 FR FR8123864A patent/FR2496461B1/fr not_active Expired
- 1981-12-21 AU AU78720/81A patent/AU545475B2/en not_active Expired
- 1981-12-21 DE DE19813150557 patent/DE3150557A1/de active Granted
- 1981-12-21 GB GB8138417A patent/GB2090739B/en not_active Expired
- 1981-12-21 PH PH26660A patent/PH18488A/en unknown
- 1981-12-21 BE BE0/206891A patent/BE891557A/fr not_active IP Right Cessation
- 1981-12-21 JP JP56206798A patent/JPS57130913A/ja active Granted
-
1986
- 1986-12-30 MY MY144/86A patent/MY8600144A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE3150557C2 (ja) | 1991-10-02 |
AR226763A1 (es) | 1982-08-13 |
FR2496461B1 (fr) | 1985-07-12 |
GB2090739B (en) | 1984-09-19 |
JPH044297B2 (ja) | 1992-01-27 |
AU7872081A (en) | 1982-07-01 |
GB2090739A (en) | 1982-07-21 |
FR2496461A1 (fr) | 1982-06-25 |
MY8600144A (en) | 1986-12-31 |
AU545475B2 (en) | 1985-07-18 |
PH18488A (en) | 1985-08-02 |
DE3150557A1 (de) | 1982-09-02 |
JPS57130913A (en) | 1982-08-13 |
BE891557A (fr) | 1982-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry | ||
MKEX | Expiry |
Effective date: 20001129 |