GB2090739B - Directly compressible acetaminophen granulation - Google Patents

Directly compressible acetaminophen granulation

Info

Publication number
GB2090739B
GB2090739B GB8138417A GB8138417A GB2090739B GB 2090739 B GB2090739 B GB 2090739B GB 8138417 A GB8138417 A GB 8138417A GB 8138417 A GB8138417 A GB 8138417A GB 2090739 B GB2090739 B GB 2090739B
Authority
GB
United Kingdom
Prior art keywords
directly compressible
compressible acetaminophen
acetaminophen granulation
granulation
directly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8138417A
Other versions
GB2090739A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Monsanto Co
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of GB2090739A publication Critical patent/GB2090739A/en
Application granted granted Critical
Publication of GB2090739B publication Critical patent/GB2090739B/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8138417A 1980-12-22 1981-12-21 Directly compressible acetaminophen granulation Expired GB2090739B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21929080A 1980-12-22 1980-12-22

Publications (2)

Publication Number Publication Date
GB2090739A GB2090739A (en) 1982-07-21
GB2090739B true GB2090739B (en) 1984-09-19

Family

ID=22818680

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8138417A Expired GB2090739B (en) 1980-12-22 1981-12-21 Directly compressible acetaminophen granulation

Country Status (10)

Country Link
JP (1) JPS57130913A (en)
AR (1) AR226763A1 (en)
AU (1) AU545475B2 (en)
BE (1) BE891557A (en)
CA (1) CA1157776A (en)
DE (1) DE3150557A1 (en)
FR (1) FR2496461B1 (en)
GB (1) GB2090739B (en)
MY (1) MY8600144A (en)
PH (1) PH18488A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4661521A (en) * 1984-04-30 1987-04-28 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
JPS61145111A (en) * 1984-12-20 1986-07-02 Lion Corp Production of tablet
US4757090A (en) * 1986-07-14 1988-07-12 Mallinckrodt, Inc. Direct tableting acetaminophen compositions
DE3636209A1 (en) * 1986-10-24 1988-04-28 Lentia Gmbh METHOD FOR PRODUCING A BINDER-FREE TABLET-TABLE CELIPROLOL HYDROCHLORIDE GRANULATE
ES2058288T3 (en) * 1987-07-08 1994-11-01 American Home Prod COMPOSITIONS OF IBUPROFEN DRIED BY ATOMIZATION.
DE3830749A1 (en) * 1987-09-11 1989-03-30 Squibb & Sons Inc MEDICAMENT IN THE FORM OF HIGH MEDICAL CONCENTRATED CONCENTRATES AND METHOD FOR THE PRODUCTION THEREOF
FR2638971B1 (en) * 1988-11-15 1993-01-08 Vacher Dominique INSTANTLY AND / OR INSTANT DISSOLUTION TABLET
FR2672212B1 (en) * 1991-02-04 1993-05-28 Lille Ii Universite PARACETAMOL CRYSTALS FOR DIRECT COMPRESSION, PROCESS FOR PREPARING SUCH CRYSTALS, AND TABLET OBTAINED WITH SUCH CRYSTALS.
JPH0656659A (en) * 1992-06-10 1994-03-01 Natl Sci Council Pharmaceutical composition which can be directly made into tablet and preparation of said tablet
DE4327462A1 (en) * 1993-08-16 1995-02-23 Carl Heinrich Dr Weischer N-Acetyl-p-aminophenol derivatives for controlling pain

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1390032A (en) * 1971-08-27 1975-04-09 Sterling Winthrop Group Ltd Pharmaceutical compositions
JPS535725B2 (en) * 1973-03-05 1978-03-01
US3873694A (en) * 1973-09-27 1975-03-25 Cpc International Inc Direct compression tabletting composition and pharmaceutical tablets produced therefrom
US4097606A (en) * 1975-10-08 1978-06-27 Bristol-Myers Company APAP Tablet containing an alkali metal carboxymethylated starch and processes for manufacturing same
JPS5344618A (en) * 1976-10-04 1978-04-21 Takeda Chem Ind Ltd Preparation of tablet
DE2713197A1 (en) * 1977-03-25 1978-10-05 Bayer Ag Paracetamol spray dried granulate - contg. 0.5-3 wt. per cent polyvinyl-pyrrolidone and less than 0.3 per cent water

Also Published As

Publication number Publication date
DE3150557C2 (en) 1991-10-02
CA1157776A (en) 1983-11-29
AR226763A1 (en) 1982-08-13
FR2496461B1 (en) 1985-07-12
JPH044297B2 (en) 1992-01-27
AU7872081A (en) 1982-07-01
GB2090739A (en) 1982-07-21
FR2496461A1 (en) 1982-06-25
MY8600144A (en) 1986-12-31
AU545475B2 (en) 1985-07-18
PH18488A (en) 1985-08-02
DE3150557A1 (en) 1982-09-02
JPS57130913A (en) 1982-08-13
BE891557A (en) 1982-06-21

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20011220