CA1152981A - Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof - Google Patents

Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof

Info

Publication number
CA1152981A
CA1152981A CA000346954A CA346954A CA1152981A CA 1152981 A CA1152981 A CA 1152981A CA 000346954 A CA000346954 A CA 000346954A CA 346954 A CA346954 A CA 346954A CA 1152981 A CA1152981 A CA 1152981A
Authority
CA
Canada
Prior art keywords
acid
dioxide
added
ethyl acetate
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000346954A
Other languages
English (en)
French (fr)
Inventor
Robert A. Volkmann
Ronnie D. Carroll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1152981A publication Critical patent/CA1152981A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA000346954A 1979-03-05 1980-03-04 Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof Expired CA1152981A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1780879A 1979-03-05 1979-03-05
US17,808 1979-03-05

Publications (1)

Publication Number Publication Date
CA1152981A true CA1152981A (en) 1983-08-30

Family

ID=21784649

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000346954A Expired CA1152981A (en) 1979-03-05 1980-03-04 Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof

Country Status (6)

Country Link
JP (2) JPS55120588A (ja)
BE (1) BE882028A (ja)
CA (1) CA1152981A (ja)
GT (1) GT198062836A (ja)
PH (1) PH17433A (ja)
ZA (1) ZA80646B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN159362B (ja) * 1981-03-23 1987-05-09 Pfizer
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
US4393001A (en) 1981-03-23 1983-07-12 Pfizer Inc. Intermediates for production of 1,1-dioxopenicillanoyloxymethyl 6-(2-amino-2-phenylacetamido)penicillanates
JPS62249988A (ja) * 1986-04-22 1987-10-30 Taiho Yakuhin Kogyo Kk ２β−ハロゲノメチル−２α−メチルペナム−３α−カルボン酸誘導体の製造法
US4835674A (en) * 1986-07-28 1989-05-30 Bull Hn Information Systems Inc. Computer network system for multiple processing elements

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203992A (en) * 1978-12-11 1980-05-20 E. R. Squibb & Sons, Inc. β-Bromopenicillanic acid sulfone
JPS5598186A (en) * 1979-01-10 1980-07-25 Beecham Group Ltd Manufacture of penicillin derivative

Also Published As

Publication number Publication date
JPS55120588A (en) 1980-09-17
JPS60120884A (ja) 1985-06-28
ZA80646B (en) 1981-02-25
BE882028A (fr) 1980-09-03
PH17433A (en) 1984-08-23
GT198062836A (es) 1981-09-29
JPS6145993B2 (ja) 1986-10-11

Similar Documents

Publication Publication Date Title
CA1080713A (en) Process for the manufacture of 3-substituted-hydroxy-crotonic and isocrotonic acid derivatives
FR2465737A1 (fr) 7-(2-(2-amino-4-thiazolyl)-2 - ((1-carboxy-1,1 - dialkyl)alcoxyimino)acetamido)cephem sulfoxydes a action antibacterienne
FR2472574A1 (fr) Derives de cephalosporine et composition pharmaceutique les contenant
CA1152981A (en) Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof
CA1150242A (en) ACETOXYMETHYL PENAM COMPOUNDS AS .beta.-LACTAMASE INHIBITORS
US4420426A (en) 6-Alpha-halopenicillanic acid 1,1-dioxides
KR850001339B1 (ko) 페니실란산 1,1-디옥사이드 및 그의 에스테르의 제조방법
CH648850A5 (de) Penicillansaeure-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel.
US5580865A (en) 2,2-disubstituted cephem sulphones
CA1213581A (en) Process and intermediates for production of 1,1- dioxopenicillanoyloxymethyl 6-(2-amino-2- phenylacetamido) penicillanates
US4714761A (en) 6,6-dihalopenicillanic acid 1,1-dioxides and process
BE875054A (fr) Composes analogues aux cephalosporines
US4762920A (en) 6,6-Dihalopenicillanic acid 1,1-dioxides
CA1152982A (en) Process and intermediates for penicillanic acid, 1,1-dioxide and esters thereof
CA1165759A (en) 7.alpha.-METHOXYCEPHALOSPORIN DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND ANTIBACTERIAL DRUGS CONTAINING THE SAME
CA1063108A (en) Azetidinone derivatives and process for preparation thereof
FR2474504A1 (fr) Nouvelles thiovinyl-3 cephalosporines, leur preparation et les medicaments qui les contiennent
JPH0215078A (ja) 抗生物質の回収方法およびその新規な薬学的に許容され得る塩
FR2549835A1 (fr) Acides peneme-carboxyliques, leur preparation et leur utilisation therapeutique, notamment en tant qu'agents antibacteriens
CA1086755A (en) Process for the manufacture of 3-methylene-butyric acid derivatives
CA1129773A (en) PENICILLANIC ACID 1,1-DIOXIDES AS .beta.-LACTAMASE INHIBITORS
CA1175809A (en) 2.beta.-CHLOROMETHYL-2.alpha.-METHYLPENAM-3.alpha.-CARBOXYLIC ACID SULFONE AND SALTS AND ESTERS THEREOF
CA1132046A (en) Combinations of penicillanic acid 1,1-dioxide with 7-(d-2-¬4-ethylpiperazin-2,3-dione-1- carboxamido|-2-¬4-hydroxyphenyl|acetamido) -3-(¬1-methyl-5-tetrazolyl|thiomethyl) -3-desacetoxymethylcephalosporanic acid
GB2184722A (en) 7 - hydroxy/amino-cephalosporin antibiotics
JPS61106582A (ja) セフエム誘導体

Legal Events

Date Code Title Description
MKEX Expiry