CA1151643A - Protease inhibitors - Google Patents

Protease inhibitors

Info

Publication number
CA1151643A
CA1151643A CA000374189A CA374189A CA1151643A CA 1151643 A CA1151643 A CA 1151643A CA 000374189 A CA000374189 A CA 000374189A CA 374189 A CA374189 A CA 374189A CA 1151643 A CA1151643 A CA 1151643A
Authority
CA
Canada
Prior art keywords
compound
aluminum
protease inhibitor
formula
acidic protease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000374189A
Other languages
English (en)
French (fr)
Inventor
Shinichi Kojima
Ten Koide
Shigeo Ogino
Toshiro Tsuchiya
Yoshito Kameno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of CA1151643A publication Critical patent/CA1151643A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Enzymes And Modification Thereof (AREA)
CA000374189A 1980-04-16 1981-03-30 Protease inhibitors Expired CA1151643A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5072580A JPS56147718A (en) 1980-04-16 1980-04-16 Acidic protease inhibitor and antiulcerative composed thereof
JP50725/80 1980-04-16

Publications (1)

Publication Number Publication Date
CA1151643A true CA1151643A (en) 1983-08-09

Family

ID=12866832

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000374189A Expired CA1151643A (en) 1980-04-16 1981-03-30 Protease inhibitors

Country Status (10)

Country Link
US (1) US4348386A (https=)
EP (1) EP0038132B1 (https=)
JP (1) JPS56147718A (https=)
AT (1) ATE4978T1 (https=)
AU (1) AU540224B2 (https=)
CA (1) CA1151643A (https=)
DE (1) DE3161155D1 (https=)
DK (1) DK164581A (https=)
ES (1) ES501405A0 (https=)
HU (1) HU185253B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531951A1 (fr) * 1982-08-17 1984-02-24 Sanofi Sa Derives peptidiques inhibiteurs de proteases acides, procede pour leur preparation et medicaments qui en contiennent
FI854634A0 (fi) * 1985-11-22 1985-11-22 Labsystems Oy Foerfarande foer bestaemning av proteolytisk aktivitet.
US4866040A (en) * 1986-01-06 1989-09-12 Alfred Stracher Aminocarnitine directed pharmaceutical agents
US5833946A (en) * 1995-06-06 1998-11-10 Bayer Corporation Dissemination of fungal infections: animal model and method of prophylaxis
US6706280B2 (en) * 1998-08-19 2004-03-16 Bracco Research S.A. Carboxylated phosphatidic acid esters

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3840516A (en) * 1969-06-13 1974-10-08 Microbial Chem Res Found Biologically active substance,pepstatin and production processes thereof
JPS5625315B2 (https=) * 1973-11-15 1981-06-11
US4050989A (en) * 1974-12-05 1977-09-27 Eisai Co., Ltd. Process of preparing desacyl-pepsidine with bacillus pumilus
DE2660964C2 (https=) * 1975-09-12 1987-07-16 Sumitomo Chemical Co., Ltd., Osaka, Jp

Also Published As

Publication number Publication date
US4348386A (en) 1982-09-07
AU6859781A (en) 1981-10-22
JPS6111935B2 (https=) 1986-04-05
EP0038132A3 (en) 1982-03-17
ES8203831A1 (es) 1982-04-01
JPS56147718A (en) 1981-11-16
DE3161155D1 (en) 1983-11-17
EP0038132A2 (en) 1981-10-21
DK164581A (da) 1981-10-17
EP0038132B1 (en) 1983-10-12
HU185253B (en) 1984-12-28
AU540224B2 (en) 1984-11-08
ES501405A0 (es) 1982-04-01
ATE4978T1 (de) 1983-10-15

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Legal Events

Date Code Title Description
MKEX Expiry