GB925001A - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
GB925001A
GB925001A GB3332760A GB3332760A GB925001A GB 925001 A GB925001 A GB 925001A GB 3332760 A GB3332760 A GB 3332760A GB 3332760 A GB3332760 A GB 3332760A GB 925001 A GB925001 A GB 925001A
Authority
GB
United Kingdom
Prior art keywords
magnesium
aqueous
aluminium
sulphate
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3332760A
Inventor
Peter Derek Fielding
Derek Betteridge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt and Sons Ltd
Original Assignee
Reckitt and Sons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt and Sons Ltd filed Critical Reckitt and Sons Ltd
Priority to GB3332760A priority Critical patent/GB925001A/en
Publication of GB925001A publication Critical patent/GB925001A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00—Silicon; Compounds thereof
    • C01B33/20—Silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An antacid composition is produced by mixing aqueous sodium aluminate with sodium silicate and adding an aqueous solution of an aluminium salt followed by an aqueous magnesium salt solution, yielding a mixture of sodium, magnesium, aluminium silicate and basic magnesium aluminate. The additions may be carried out at room temperature with continuous stirring. Aluminium salts used are, chloride, bromide, nitrate or sulphate and magnesium salts are chloride, bromide, nitrate, iodide, acetate or sulphate of at least 10% w/v concentration. The product is desirably washed free of soluble salts and should contain a minimum of basic aluminium sulphate. According to Example (1) aqueous sodium aluminate was added in a fine stream to aqueous sodium metasilicate with stirring, aqueous aluminium sulphate was then added in a similar way 15 mins. later. Aqueous magnesium sulphate was then added and the mixture stirred for 1 hour, centrifuged, worked free from sulphate filtered and then dried. The dry product was powdered or dry granulated. In further examples the uses of various aluminium and magnesium salts are exemplified. The antacid composition is compounded into tablets or used as a liquid suspension for the treatment of hyperacidity.ALSO:Sodium, magnesium, aluminium silicate and basic magnesium aluminate are prepared as an antacid composition (see Group III) and are then compounded into tablets or used as an aqueous suspension. Ingredients used for tablets are antacid composition, sugar, starch, saccharin, magnesium stearate, talc and oil of peppermint. A suspension of the compound is produced by mixing with water, sweetening and flavouring materials.
GB3332760A 1960-09-28 1960-09-28 Pharmaceutical compositions Expired GB925001A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3332760A GB925001A (en) 1960-09-28 1960-09-28 Pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3332760A GB925001A (en) 1960-09-28 1960-09-28 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
GB925001A true GB925001A (en) 1963-05-01

Family

ID=10351507

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3332760A Expired GB925001A (en) 1960-09-28 1960-09-28 Pharmaceutical compositions

Country Status (1)

Country Link
GB (1) GB925001A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767994A1 (en) * 1967-07-10 1971-10-21 Nicolle & Beausire Process for the manufacture of a product with an antacid and adsorbent effect
US4339421A (en) * 1978-09-07 1982-07-13 Laboratoires Om Societe Anonyme Synthetic magnesium aluminosilicate, process for the manufacture thereof, and pharmaceutical compositions containing same
US11643481B2 (en) 2018-02-02 2023-05-09 W.R. Grace & Co.-Conn. Antacids for polymers

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767994A1 (en) * 1967-07-10 1971-10-21 Nicolle & Beausire Process for the manufacture of a product with an antacid and adsorbent effect
US4339421A (en) * 1978-09-07 1982-07-13 Laboratoires Om Societe Anonyme Synthetic magnesium aluminosilicate, process for the manufacture thereof, and pharmaceutical compositions containing same
US11643481B2 (en) 2018-02-02 2023-05-09 W.R. Grace & Co.-Conn. Antacids for polymers

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