CA1112648A - 2-[3,4-disubstituted-phenylimino]-imidazolidines - Google Patents

2-[3,4-disubstituted-phenylimino]-imidazolidines

Info

Publication number
CA1112648A
CA1112648A CA342,041A CA342041A CA1112648A CA 1112648 A CA1112648 A CA 1112648A CA 342041 A CA342041 A CA 342041A CA 1112648 A CA1112648 A CA 1112648A
Authority
CA
Canada
Prior art keywords
fluoro
compound
formula
imidazolidine
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA342,041A
Other languages
English (en)
French (fr)
Inventor
Helmut Stahle
Herbert Koppe
Werner Kummer
Alexander Walland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of CA1112648A publication Critical patent/CA1112648A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CA342,041A 1978-12-18 1979-12-17 2-[3,4-disubstituted-phenylimino]-imidazolidines Expired CA1112648A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP2854659.0 1978-12-18
DE19782854659 DE2854659A1 (de) 1978-12-18 1978-12-18 Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
CA1112648A true CA1112648A (en) 1981-11-17

Family

ID=6057553

Family Applications (1)

Application Number Title Priority Date Filing Date
CA342,041A Expired CA1112648A (en) 1978-12-18 1979-12-17 2-[3,4-disubstituted-phenylimino]-imidazolidines

Country Status (18)

Country Link
EP (1) EP0012822B1 (enExample)
JP (1) JPS5583754A (enExample)
AT (1) ATE1903T1 (enExample)
AU (1) AU526539B2 (enExample)
CA (1) CA1112648A (enExample)
DE (2) DE2854659A1 (enExample)
DK (1) DK146821C (enExample)
ES (3) ES8102100A1 (enExample)
FI (1) FI68814C (enExample)
GR (1) GR73913B (enExample)
IE (1) IE49239B1 (enExample)
IL (1) IL58971A (enExample)
NO (1) NO148555C (enExample)
NZ (1) NZ192426A (enExample)
PH (1) PH22130A (enExample)
PT (1) PT70592A (enExample)
YU (1) YU41901B (enExample)
ZA (1) ZA796832B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6066740A (en) * 1997-11-25 2000-05-23 The Procter & Gamble Company Process for making 2-amino-2-imidazoline, guanidine and 2-amino-3,4,5,6-tetrahydropyrimidine derivatives
US6316637B1 (en) 1994-08-04 2001-11-13 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2933930A1 (de) * 1979-08-22 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
HU192986B (en) * 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives
DE19514579A1 (de) * 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
PE28099A1 (es) * 1996-11-25 1999-03-31 Procter & Gamble Proceso para hacer derivados de 2-amino-2-imidazolina, guanidina y 2-amino-3,4,5,6-tetrahidropirimidina
CN111303038A (zh) * 2020-03-18 2020-06-19 滨州德润化工有限责任公司 一种油田水处理用缓蚀剂两性咪唑啉制作工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL123037C (enExample) * 1963-10-04
BE687656A (enExample) * 1965-10-01 1967-03-30
DE1545628A1 (de) * 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2)
AT278775B (de) * 1967-01-19 1970-02-10 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von Δ<2>-Imidazolinderivaten und ihren Salzen
AT330769B (de) * 1974-04-05 1976-07-26 Chemie Linz Ag Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen
DE2806775A1 (de) * 1978-02-17 1979-08-30 Boehringer Sohn Ingelheim Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316637B1 (en) 1994-08-04 2001-11-13 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
US6403626B1 (en) 1994-08-04 2002-06-11 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
US6436982B1 (en) 1994-08-04 2002-08-20 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
US6066740A (en) * 1997-11-25 2000-05-23 The Procter & Gamble Company Process for making 2-amino-2-imidazoline, guanidine and 2-amino-3,4,5,6-tetrahydropyrimidine derivatives

Also Published As

Publication number Publication date
DE2964166D1 (en) 1983-01-05
JPH0118071B2 (enExample) 1989-04-03
YU41901B (en) 1988-02-29
NZ192426A (en) 1984-07-06
IE49239B1 (en) 1985-09-04
FI793948A7 (fi) 1980-06-19
DK146821C (da) 1984-06-25
DK146821B (da) 1984-01-16
ES486967A0 (es) 1981-02-16
AU526539B2 (en) 1983-01-20
ES8100272A1 (es) 1980-11-01
ES486970A0 (es) 1980-12-16
IL58971A (en) 1984-03-30
EP0012822A1 (de) 1980-07-09
JPS5583754A (en) 1980-06-24
NO148555C (no) 1983-11-23
PT70592A (de) 1980-01-01
AU5389379A (en) 1980-06-26
YU308979A (en) 1983-04-30
DE2854659A1 (de) 1980-07-10
ATE1903T1 (de) 1982-12-15
ES8102100A1 (es) 1980-12-16
FI68814C (fi) 1985-11-11
ZA796832B (en) 1981-08-26
IL58971A0 (en) 1980-03-31
FI68814B (fi) 1985-07-31
ES8103054A1 (es) 1981-02-16
DK537179A (da) 1980-06-19
NO148555B (no) 1983-07-25
ES486971A0 (es) 1980-11-01
PH22130A (en) 1988-06-01
EP0012822B1 (de) 1982-12-01
NO794114L (no) 1980-06-19
IE792447L (en) 1980-06-18
GR73913B (enExample) 1984-05-22

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Legal Events

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