CA1101426A - 4-diphenylmethylene-1-hydroxybenzyl-piperidine compounds - Google Patents
4-diphenylmethylene-1-hydroxybenzyl-piperidine compoundsInfo
- Publication number
- CA1101426A CA1101426A CA294,674A CA294674A CA1101426A CA 1101426 A CA1101426 A CA 1101426A CA 294674 A CA294674 A CA 294674A CA 1101426 A CA1101426 A CA 1101426A
- Authority
- CA
- Canada
- Prior art keywords
- diphenylmethylene
- piperidine
- process according
- hydroxybenzyl
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB931/77 | 1977-01-11 | ||
GB931/77A GB1542823A (en) | 1977-01-11 | 1977-01-11 | Piperidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1101426A true CA1101426A (en) | 1981-05-19 |
Family
ID=9713045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA294,674A Expired CA1101426A (en) | 1977-01-11 | 1978-01-10 | 4-diphenylmethylene-1-hydroxybenzyl-piperidine compounds |
Country Status (22)
Country | Link |
---|---|
JP (1) | JPS5387367A (it) |
BE (1) | BE862769A (it) |
BG (1) | BG28574A3 (it) |
CA (1) | CA1101426A (it) |
CS (1) | CS195652B2 (it) |
DD (1) | DD134089A5 (it) |
DE (1) | DE2800919A1 (it) |
DK (1) | DK5778A (it) |
ES (1) | ES465861A1 (it) |
FI (1) | FI780028A (it) |
FR (1) | FR2376846A1 (it) |
GB (1) | GB1542823A (it) |
IL (1) | IL53766A0 (it) |
IT (1) | IT1103117B (it) |
LU (1) | LU78839A1 (it) |
NL (1) | NL7800146A (it) |
NO (1) | NO780040L (it) |
PL (1) | PL203912A1 (it) |
PT (1) | PT67511B (it) |
SE (1) | SE7800184L (it) |
SU (2) | SU772482A3 (it) |
ZA (1) | ZA78158B (it) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4650874A (en) * | 1984-11-26 | 1987-03-17 | G. D. Searle & Co. | N-(aralkoxybenzyl)-4(benzhydryl) piperidines |
US4628095A (en) * | 1985-06-05 | 1986-12-09 | G. D. Searle & Co. | Substituted N-benzyl-4-(benzhydryl) piperidines |
EP0235463A3 (en) * | 1985-12-20 | 1990-01-17 | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents |
GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
DE19681115D2 (de) * | 1995-12-20 | 1999-11-25 | Eckhart Pein | Neue 1-Phenylalkyl/Alkylen-4-(.Alpha.-Hydroxydiphenylmethyl)-Piperidin Derivative und ihre Verwendung als Serotonin Antagonisten |
EP1047674B1 (en) * | 1998-01-16 | 2005-03-30 | Eisai Co., Ltd. | Process for production of donepezil derivatives |
CN100384421C (zh) * | 2002-12-18 | 2008-04-30 | 拜尔农科股份公司 | N-(取代的芳基甲基)-4-(二取代的甲基)哌啶和吡啶 |
JP4730096B2 (ja) * | 2003-05-20 | 2011-07-20 | 味の素株式会社 | 新規ピペリジン誘導体 |
-
1977
- 1977-01-11 GB GB931/77A patent/GB1542823A/en not_active Expired
-
1978
- 1978-01-05 FI FI780028A patent/FI780028A/fi not_active Application Discontinuation
- 1978-01-05 NL NL7800146A patent/NL7800146A/xx not_active Application Discontinuation
- 1978-01-05 NO NO780040A patent/NO780040L/no unknown
- 1978-01-05 DK DK5778A patent/DK5778A/da unknown
- 1978-01-09 SE SE7800184A patent/SE7800184L/xx unknown
- 1978-01-09 CS CS78170A patent/CS195652B2/cs unknown
- 1978-01-09 IL IL53766A patent/IL53766A0/xx unknown
- 1978-01-09 FR FR7800616A patent/FR2376846A1/fr active Granted
- 1978-01-09 BG BG038343A patent/BG28574A3/xx unknown
- 1978-01-10 LU LU78839A patent/LU78839A1/xx unknown
- 1978-01-10 IT IT47573/78A patent/IT1103117B/it active
- 1978-01-10 BE BE1008634A patent/BE862769A/xx not_active IP Right Cessation
- 1978-01-10 ES ES465861A patent/ES465861A1/es not_active Expired
- 1978-01-10 PT PT67511A patent/PT67511B/pt unknown
- 1978-01-10 CA CA294,674A patent/CA1101426A/en not_active Expired
- 1978-01-10 PL PL20391278A patent/PL203912A1/xx unknown
- 1978-01-10 ZA ZA00780158A patent/ZA78158B/xx unknown
- 1978-01-10 DD DD78203161A patent/DD134089A5/xx unknown
- 1978-01-10 SU SU782562702A patent/SU772482A3/ru active
- 1978-01-10 JP JP147578A patent/JPS5387367A/ja active Granted
- 1978-01-10 DE DE19782800919 patent/DE2800919A1/de not_active Withdrawn
- 1978-07-17 SU SU782637199A patent/SU990761A1/ru active
Also Published As
Publication number | Publication date |
---|---|
NL7800146A (nl) | 1978-07-13 |
FR2376846A1 (fr) | 1978-08-04 |
FI780028A (fi) | 1978-07-12 |
PT67511B (fr) | 1979-06-11 |
BE862769A (fr) | 1978-07-10 |
DE2800919A1 (de) | 1978-07-13 |
DD134089A5 (de) | 1979-02-07 |
SU772482A3 (ru) | 1980-10-15 |
BG28574A3 (en) | 1980-05-15 |
PT67511A (fr) | 1978-02-01 |
PL203912A1 (pl) | 1979-06-04 |
NO780040L (no) | 1978-07-12 |
DK5778A (da) | 1978-07-12 |
JPS5387367A (en) | 1978-08-01 |
FR2376846B1 (it) | 1983-02-04 |
LU78839A1 (fr) | 1978-09-18 |
JPS6125031B2 (it) | 1986-06-13 |
CS195652B2 (en) | 1980-02-29 |
IT1103117B (it) | 1985-10-14 |
IT7847573A0 (it) | 1978-01-10 |
GB1542823A (en) | 1979-03-28 |
IL53766A0 (en) | 1978-04-30 |
ZA78158B (en) | 1978-10-25 |
SE7800184L (sv) | 1978-07-12 |
SU990761A1 (ru) | 1983-01-23 |
ES465861A1 (es) | 1978-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MKEX | Expiry |