CA1093439A - Assay for bilirubin - Google Patents
Assay for bilirubinInfo
- Publication number
- CA1093439A CA1093439A CA292,510A CA292510A CA1093439A CA 1093439 A CA1093439 A CA 1093439A CA 292510 A CA292510 A CA 292510A CA 1093439 A CA1093439 A CA 1093439A
- Authority
- CA
- Canada
- Prior art keywords
- bilirubin
- layer
- detectable
- carrier
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- CVQGBZGCMIYEGG-UHFFFAOYSA-N ethane-1,2-diamine;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound NCCN.OC(=O)CC(O)(C(O)=O)CC(O)=O CVQGBZGCMIYEGG-UHFFFAOYSA-N 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 229960000890 hydrocortisone Drugs 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000005470 impregnation Methods 0.000 description 1
- 230000003455 independent Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000003475 lamination Methods 0.000 description 1
- 229910000464 lead oxide Inorganic materials 0.000 description 1
- 229950008325 levothyroxine Drugs 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 239000006193 liquid solution Substances 0.000 description 1
- 208000007903 liver failure Diseases 0.000 description 1
- 231100000835 liver failure Toxicity 0.000 description 1
- 230000002101 lytic effect Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000004379 membrane Anatomy 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000001457 metallic cations Chemical class 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- UYDLBVPAAFVANX-UHFFFAOYSA-N octylphenoxy polyethoxyethanol Chemical compound CC(C)(C)CC(C)(C)C1=CC=C(OCCOCCOCCOCCO)C=C1 UYDLBVPAAFVANX-UHFFFAOYSA-N 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- YEXPOXQUZXUXJW-UHFFFAOYSA-N oxolead Chemical compound [Pb]=O YEXPOXQUZXUXJW-UHFFFAOYSA-N 0.000 description 1
- 150000002942 palmitic acid derivatives Chemical class 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 125000005496 phosphonium group Chemical group 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000003495 polar organic solvent Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000139 polyethylene terephthalate Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000186 progesterone Substances 0.000 description 1
- 229960003387 progesterone Drugs 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 238000012207 quantitative assay Methods 0.000 description 1
- 238000012113 quantitative test Methods 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000002310 reflectometry Methods 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 210000003786 sclera Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 239000012086 standard solution Substances 0.000 description 1
- 150000008054 sulfonate salts Chemical class 0.000 description 1
- 125000000542 sulfonic acid group Chemical group 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- FBWNMEQMRUMQSO-UHFFFAOYSA-N tergitol NP-9 Chemical compound CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 1
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000001052 yellow pigment Substances 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/728—Bilirubin; including biliverdin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/145555—Hetero-N
- Y10T436/146666—Bile pigment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/759,530 US4069016A (en) | 1977-01-14 | 1977-01-14 | Assay for bilirubin |
| US759,530 | 1991-09-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1093439A true CA1093439A (en) | 1981-01-13 |
Family
ID=25056001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA292,510A Expired CA1093439A (en) | 1977-01-14 | 1977-12-06 | Assay for bilirubin |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4069016A (en:Method) |
| JP (1) | JPS5389797A (en:Method) |
| BE (1) | BE862957A (en:Method) |
| CA (1) | CA1093439A (en:Method) |
| DE (1) | DE2801477C2 (en:Method) |
| FR (1) | FR2377633A1 (en:Method) |
| GB (1) | GB1599679A (en:Method) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4230601A (en) * | 1978-05-03 | 1980-10-28 | Eastman Kodak Company | Calibrator composition based upon dialyzed blood serum |
| US4260392A (en) * | 1978-07-07 | 1981-04-07 | Technicon Instruments Corporation | Method and apparatus for obtaining an aliquot of a liquid in a gel medium |
| US4204839A (en) * | 1978-08-09 | 1980-05-27 | Eastman Kodak Company | Fluorimetric analysis method for bilirubin |
| US4230456A (en) * | 1978-08-30 | 1980-10-28 | Eastman Kodak Company | Element and assay for albumin |
| US4274832A (en) * | 1979-02-12 | 1981-06-23 | Eastman Kodak Company | Analytical element and method for analysis of multiple analytes |
| US4269938A (en) * | 1979-03-08 | 1981-05-26 | Eastman Kodak Company | Assay of peroxidatively active materials |
| CA1128333A (en) * | 1979-07-11 | 1982-07-27 | Tai-Wing Wu | Determination of conjugated and unconjugated bilirubin |
| US4412005A (en) * | 1979-10-25 | 1983-10-25 | Eastman Kodak Company | Determination of total bilirubin |
| JPS5737262A (en) * | 1980-08-19 | 1982-03-01 | Fuji Photo Film Co Ltd | Analyzing method for bilirubin and multilayer analysis material for said method |
| US4459358A (en) * | 1982-12-29 | 1984-07-10 | Polaroid Corporation | Multilayer element for analysis |
| US4788153A (en) * | 1986-10-14 | 1988-11-29 | Eastman Kodak Company | Method for the determination of bilirubin and an element useful therein |
| EP0345460B1 (en) * | 1988-06-09 | 1995-09-06 | Abbott Laboratories | Method and device employing covalently immobilized colored dyes |
| WO1993016386A1 (en) * | 1992-02-10 | 1993-08-19 | Actimed Laboratories, Inc. | Method for immobilizing dye on substrates |
| US5286450A (en) * | 1992-06-01 | 1994-02-15 | Eastman Kodak Company | Bilirubin assay using crosslinkable polymers |
| US5583051A (en) * | 1993-02-03 | 1996-12-10 | The United States Of America As Represented By The Department Of Energy | Use of a fiber optic probe for organic species determination |
| US5783407A (en) * | 1996-04-05 | 1998-07-21 | Beckman Instruments, Inc. | Method of measuring bilirubin |
| GB9612264D0 (en) * | 1996-06-12 | 1996-08-14 | Samsoondar James | Quality control material for monitoring calibration of instruments designed to measure serum and plasma specimen integrity |
| US6828152B2 (en) * | 1996-06-12 | 2004-12-07 | Spectromedical Inc. | Quality control material for reagentless measurement of analytes |
| US7157282B2 (en) * | 1996-06-12 | 2007-01-02 | Spectromedical Inc. | Quality control material for reagentless measurement of analytes |
| US6074881A (en) * | 1998-08-03 | 2000-06-13 | Bayer Corporation | Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity |
| US6949384B2 (en) * | 2001-12-21 | 2005-09-27 | Spectromedical Inc. | Method for monitoring degradation of Hb-based blood substitutes |
| US7449339B2 (en) * | 1999-11-23 | 2008-11-11 | Nir Diagnostics Inc. | Spectroscopic method and apparatus for total hemoglobin measurement |
| US20050037505A1 (en) * | 2000-05-11 | 2005-02-17 | James Samsoondar | Spectroscopic method and apparatus for analyte measurement |
| US20050123439A1 (en) * | 2003-12-09 | 2005-06-09 | Eastman Kodak Company | Device for sensing contaminants |
| US20050123440A1 (en) * | 2003-12-09 | 2005-06-09 | Eastman Kodak Company | Sensor for contaminants |
| US20050214161A1 (en) * | 2004-03-23 | 2005-09-29 | Gupta Surendra K | Test device for simultaneous measurement of multiple analytes in a single sample |
| ES2383905T3 (es) * | 2004-12-13 | 2012-06-27 | Bayer Healthcare, Llc | Composiciones autolimitantes en términos de dimensión y dispositivos de ensayo para medir analitos en fluidos biológicos |
| US7939333B2 (en) * | 2005-06-17 | 2011-05-10 | University Of Maryland, Baltimore County | Metal enhanced fluorescence-based sensing methods |
| US20130345614A1 (en) | 2012-06-22 | 2013-12-26 | Viraj P. Mane | Device for extracorporeal photo-isomerization for hyperbilirubinemia, and method thereof |
| EP3676605A4 (en) * | 2017-08-30 | 2021-06-02 | Neolight LLC | BILIRUBIN ANALYSIS SYSTEM AND METHODS |
-
1977
- 1977-01-14 US US05/759,530 patent/US4069016A/en not_active Expired - Lifetime
- 1977-12-06 CA CA292,510A patent/CA1093439A/en not_active Expired
-
1978
- 1978-01-13 FR FR7800875A patent/FR2377633A1/fr active Granted
- 1978-01-13 DE DE2801477A patent/DE2801477C2/de not_active Expired
- 1978-01-14 JP JP323078A patent/JPS5389797A/ja active Granted
- 1978-01-16 BE BE184367A patent/BE862957A/xx not_active IP Right Cessation
- 1978-01-16 GB GB1674/78A patent/GB1599679A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2801477A1 (de) | 1978-07-20 |
| JPS5725783B2 (en:Method) | 1982-06-01 |
| BE862957A (fr) | 1978-07-17 |
| JPS5389797A (en) | 1978-08-07 |
| FR2377633A1 (fr) | 1978-08-11 |
| FR2377633B1 (en:Method) | 1980-07-04 |
| DE2801477C2 (de) | 1982-12-09 |
| GB1599679A (en) | 1981-10-07 |
| US4069016A (en) | 1978-01-17 |
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Legal Events
| Date | Code | Title | Description |
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| MKEX | Expiry |