CA1091656A - Spiro¬cyclopropane-1,2'-indolin|-3'-ones - Google Patents
Spiro¬cyclopropane-1,2'-indolin|-3'-onesInfo
- Publication number
- CA1091656A CA1091656A CA266,565A CA266565A CA1091656A CA 1091656 A CA1091656 A CA 1091656A CA 266565 A CA266565 A CA 266565A CA 1091656 A CA1091656 A CA 1091656A
- Authority
- CA
- Canada
- Prior art keywords
- spiro
- indoline
- cyclopropane
- carbon atoms
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP141748/1975 | 1975-11-26 | ||
| JP50141748A JPS5265267A (en) | 1975-11-26 | 1975-11-26 | Synthesis of spiro compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1091656A true CA1091656A (en) | 1980-12-16 |
Family
ID=15299270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA266,565A Expired CA1091656A (en) | 1975-11-26 | 1976-11-25 | Spiro¬cyclopropane-1,2'-indolin|-3'-ones |
Country Status (12)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284644A (en) * | 1977-01-12 | 1981-08-18 | Takeda Chemical Industries, Ltd. | Spirobenzofuranone compounds |
| US4342779A (en) * | 1977-12-27 | 1982-08-03 | Takeda Chemical Industries, Ltd. | 7-Acetylspirobenzofuranone compound |
| JPS5646879A (en) * | 1979-09-25 | 1981-04-28 | Takeda Chem Ind Ltd | Spiro compound, its preparation, and preventive and remedy for circulatory system disorder |
| US4330554A (en) * | 1980-04-23 | 1982-05-18 | Takeda Chemical Industries, Ltd. | Spirobenzofuranone compounds |
| FR2501676A1 (fr) * | 1981-03-11 | 1982-09-17 | Rhone Poulenc Spec Chim | Procede de n-alkylation de composes organiques azotes |
| BRPI0519013A2 (pt) * | 2004-12-13 | 2009-11-03 | Lilly Co Eli | composto ou esteroisÈmeros únicos, misturas de esteroisÈmeros, sais, tautÈmeros ou pró-drogas destes farmaceuticamente aceitáveis, composição farmacêutica, e, uso de um composto |
-
1975
- 1975-11-26 JP JP50141748A patent/JPS5265267A/ja active Pending
-
1976
- 1976-11-19 US US05/743,404 patent/US4105670A/en not_active Expired - Lifetime
- 1976-11-23 DK DK526476A patent/DK526476A/da unknown
- 1976-11-24 AU AU19974/76A patent/AU499472B2/en not_active Expired
- 1976-11-25 CA CA266,565A patent/CA1091656A/en not_active Expired
- 1976-11-25 GB GB49179/76A patent/GB1570596A/en not_active Expired
- 1976-11-25 SE SE7613218A patent/SE421692B/xx unknown
- 1976-11-25 DE DE19762653477 patent/DE2653477A1/de not_active Withdrawn
- 1976-11-25 FR FR7635469A patent/FR2362125A1/fr active Granted
- 1976-11-25 NL NL7613187A patent/NL7613187A/xx not_active Application Discontinuation
- 1976-11-25 BE BE172720A patent/BE848766A/xx unknown
- 1976-11-26 CH CH1494276A patent/CH623811A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2653477A1 (de) | 1977-06-08 |
| GB1570596A (en) | 1980-07-02 |
| CH623811A5 (US06397114-20020528-M00001.png) | 1981-06-30 |
| US4105670A (en) | 1978-08-08 |
| SE421692B (sv) | 1982-01-25 |
| BE848766A (fr) | 1977-05-25 |
| SE7613218L (sv) | 1977-05-27 |
| FR2362125A1 (fr) | 1978-03-17 |
| AU499472B2 (en) | 1979-04-26 |
| AU1997476A (en) | 1978-06-01 |
| NL7613187A (nl) | 1977-05-31 |
| JPS5265267A (en) | 1977-05-30 |
| DK526476A (da) | 1977-05-27 |
| FR2362125B1 (US06397114-20020528-M00001.png) | 1982-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |