CA1074318A - Process for the preparation of indoloquinolizine derivatives - Google Patents

Process for the preparation of indoloquinolizine derivatives

Info

Publication number
CA1074318A
CA1074318A CA255,768A CA255768A CA1074318A CA 1074318 A CA1074318 A CA 1074318A CA 255768 A CA255768 A CA 255768A CA 1074318 A CA1074318 A CA 1074318A
Authority
CA
Canada
Prior art keywords
ethyl
indolo
quinolizine
octahydro
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA255,768A
Other languages
English (en)
French (fr)
Inventor
Csaba Szantay
Gyorgy Kalaus
Lajos Szabo
Egon Karpati
Laszlo Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of CA1074318A publication Critical patent/CA1074318A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA255,768A 1975-06-27 1976-06-25 Process for the preparation of indoloquinolizine derivatives Expired CA1074318A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75RI00000570A HU171660B (hu) 1975-06-27 1975-06-27 Sposob poluchenija novykh oktagidro-indolo/2,3-a/-khinolizinov, ikh sterecizomerov i solej

Publications (1)

Publication Number Publication Date
CA1074318A true CA1074318A (en) 1980-03-25

Family

ID=11000979

Family Applications (1)

Application Number Title Priority Date Filing Date
CA255,768A Expired CA1074318A (en) 1975-06-27 1976-06-25 Process for the preparation of indoloquinolizine derivatives

Country Status (21)

Country Link
US (1) US4089856A (US06544258-20030408-M00015.png)
JP (1) JPS525799A (US06544258-20030408-M00015.png)
AT (1) AT351541B (US06544258-20030408-M00015.png)
AU (1) AU499923B2 (US06544258-20030408-M00015.png)
BE (1) BE843288A (US06544258-20030408-M00015.png)
BG (1) BG26535A3 (US06544258-20030408-M00015.png)
CA (1) CA1074318A (US06544258-20030408-M00015.png)
CH (1) CH624955A5 (US06544258-20030408-M00015.png)
CS (1) CS199629B2 (US06544258-20030408-M00015.png)
DD (1) DD132435A5 (US06544258-20030408-M00015.png)
DE (1) DE2625672A1 (US06544258-20030408-M00015.png)
DK (1) DK140941B (US06544258-20030408-M00015.png)
FR (1) FR2315273A1 (US06544258-20030408-M00015.png)
GB (1) GB1548671A (US06544258-20030408-M00015.png)
HU (1) HU171660B (US06544258-20030408-M00015.png)
IL (1) IL49755A (US06544258-20030408-M00015.png)
NL (1) NL7607004A (US06544258-20030408-M00015.png)
PL (1) PL97658B1 (US06544258-20030408-M00015.png)
SE (1) SE430693B (US06544258-20030408-M00015.png)
SU (1) SU619107A3 (US06544258-20030408-M00015.png)
YU (1) YU39481B (US06544258-20030408-M00015.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
HU178700B (en) * 1978-02-10 1982-06-28 Richter Gedeon Vegyeszet Process for preparing 1,1-disubstituted octahydro-indolo/2,3-a/-quinolizines
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
HU178402B (en) * 1978-08-01 1982-04-28 Richter Gedeon Vegyeszet New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
KR100392292B1 (ko) * 2000-01-07 2003-07-22 주식회사 펩트론 5원환 융합 방향족 헤테로사이클릭 화합물을 유효성분으로 하는 hcv 치료제 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454583A (en) * 1965-07-19 1969-07-08 Us Health Education & Welfare Synthesis of vincamine
HU163143B (US06544258-20030408-M00015.png) * 1971-05-07 1973-06-28
CH578001A5 (US06544258-20030408-M00015.png) * 1972-04-14 1976-07-30 Sandoz Ag
HU169916B (US06544258-20030408-M00015.png) * 1974-09-27 1977-02-28

Also Published As

Publication number Publication date
DK140941B (da) 1979-12-10
BE843288A (fr) 1976-10-18
CH624955A5 (US06544258-20030408-M00015.png) 1981-08-31
BG26535A3 (bg) 1979-04-12
AU499923B2 (en) 1979-05-03
JPS525799A (en) 1977-01-17
YU153576A (en) 1982-02-28
SE7607171L (sv) 1976-12-28
DE2625672A1 (de) 1977-01-13
AU1480176A (en) 1977-12-15
AT351541B (de) 1979-07-25
US4089856A (en) 1978-05-16
SE430693B (sv) 1983-12-05
GB1548671A (en) 1979-07-18
DK140941C (US06544258-20030408-M00015.png) 1980-06-30
FR2315273B1 (US06544258-20030408-M00015.png) 1978-11-03
YU39481B (en) 1984-12-31
DK281676A (US06544258-20030408-M00015.png) 1976-12-28
DD132435A5 (de) 1978-09-27
CS199629B2 (en) 1980-07-31
FR2315273A1 (fr) 1977-01-21
ATA415376A (de) 1979-01-15
NL7607004A (nl) 1976-12-29
PL97658B1 (pl) 1978-03-30
IL49755A (en) 1980-01-31
SU619107A3 (ru) 1978-08-05
IL49755A0 (en) 1976-08-31
HU171660B (hu) 1978-02-28

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Legal Events

Date Code Title Description
MKEX Expiry