CA1068607A - 2-cyclopropanecarboxamido-5-halothiazole as anti-inflammatory agents - Google Patents

2-cyclopropanecarboxamido-5-halothiazole as anti-inflammatory agents

Info

Publication number
CA1068607A
CA1068607A CA270,844A CA270844A CA1068607A CA 1068607 A CA1068607 A CA 1068607A CA 270844 A CA270844 A CA 270844A CA 1068607 A CA1068607 A CA 1068607A
Authority
CA
Canada
Prior art keywords
halothiazole
edema
compounds
composition
cyclopropanecarboxamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA270,844A
Other languages
English (en)
French (fr)
Inventor
Don R. Baker
Ferenc M. Pallos
Jack R. Debaun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stauffer Chemical Co
Original Assignee
Stauffer Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/676,770 external-priority patent/US4027031A/en
Application filed by Stauffer Chemical Co filed Critical Stauffer Chemical Co
Application granted granted Critical
Publication of CA1068607A publication Critical patent/CA1068607A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CA270,844A 1976-04-14 1977-02-01 2-cyclopropanecarboxamido-5-halothiazole as anti-inflammatory agents Expired CA1068607A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/676,770 US4027031A (en) 1975-04-28 1976-04-14 2-Cyclopropanecarboxamido-S-halothiazole as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
CA1068607A true CA1068607A (en) 1979-12-25

Family

ID=24715924

Family Applications (1)

Application Number Title Priority Date Filing Date
CA270,844A Expired CA1068607A (en) 1976-04-14 1977-02-01 2-cyclopropanecarboxamido-5-halothiazole as anti-inflammatory agents

Country Status (13)

Country Link
JP (1) JPS52125164A (OSRAM)
AT (1) AT350316B (OSRAM)
AU (1) AU2220177A (OSRAM)
BE (1) BE852075A (OSRAM)
CA (1) CA1068607A (OSRAM)
CH (1) CH626079A5 (OSRAM)
DE (1) DE2708327A1 (OSRAM)
FR (1) FR2348206A1 (OSRAM)
GR (1) GR66154B (OSRAM)
IL (1) IL51483A0 (OSRAM)
NL (1) NL7702432A (OSRAM)
PH (1) PH11483A (OSRAM)
PT (1) PT66258B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
DE3264595D1 (en) * 1981-01-08 1985-08-14 Mitsui Toatsu Chemicals N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
US4501750A (en) * 1981-01-13 1985-02-26 Mitsui Toatsu Kaguku Kabushiki Kaisha Thiazole compounds, a process for preparing same and a pharmaceutical composition containing the thiazole compounds
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents

Also Published As

Publication number Publication date
NL7702432A (nl) 1977-10-18
ATA98477A (de) 1978-10-15
CH626079A5 (en) 1981-10-30
GR66154B (OSRAM) 1981-01-19
DE2708327A1 (de) 1977-11-03
AU2220177A (en) 1978-08-17
FR2348206A1 (fr) 1977-11-10
FR2348206B1 (OSRAM) 1980-03-07
PH11483A (en) 1978-02-01
AT350316B (de) 1979-05-25
IL51483A0 (en) 1977-04-29
PT66258B (en) 1978-08-07
BE852075A (nl) 1977-09-05
PT66258A (en) 1977-04-01
JPS52125164A (en) 1977-10-20

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