CA1063131A - Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use - Google Patents

Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use

Info

Publication number
CA1063131A
CA1063131A CA232,800A CA232800A CA1063131A CA 1063131 A CA1063131 A CA 1063131A CA 232800 A CA232800 A CA 232800A CA 1063131 A CA1063131 A CA 1063131A
Authority
CA
Canada
Prior art keywords
reacted
acid
phosphoric acid
organic solvent
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA232,800A
Other languages
English (en)
French (fr)
Inventor
Hansjorg Eibl
Stefan Kovatchev
Walter Diembeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Application granted granted Critical
Publication of CA1063131A publication Critical patent/CA1063131A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
CA232,800A 1974-08-06 1975-08-05 Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use Expired CA1063131A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437833A DE2437833A1 (de) 1974-08-06 1974-08-06 Synthetische alkylester von phosphatidsaeure und von struckturanaloga, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
CA1063131A true CA1063131A (en) 1979-09-25

Family

ID=5922579

Family Applications (1)

Application Number Title Priority Date Filing Date
CA232,800A Expired CA1063131A (en) 1974-08-06 1975-08-05 Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use

Country Status (13)

Country Link
JP (1) JPS5143724A (zh)
AU (1) AU8368575A (zh)
BE (1) BE832181A (zh)
CA (1) CA1063131A (zh)
CH (1) CH619962A5 (zh)
DE (1) DE2437833A1 (zh)
DK (1) DK355675A (zh)
FR (1) FR2281374A1 (zh)
GB (1) GB1523481A (zh)
IE (1) IE41442B1 (zh)
IT (1) IT1044019B (zh)
LU (1) LU73149A1 (zh)
NL (1) NL7509364A (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56677Y2 (zh) * 1976-12-27 1981-01-09
DE3476770D1 (en) * 1983-04-11 1989-03-23 Meito Sangyo Kk Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2750399A (en) * 1949-12-27 1956-06-12 Monsanto Chemicals Process for alkyl phosphoryl dichlorides

Also Published As

Publication number Publication date
DE2437833A1 (de) 1976-02-26
AU8368575A (en) 1977-02-10
DK355675A (da) 1976-02-07
IE41442L (en) 1976-02-06
JPS5143724A (en) 1976-04-14
BE832181A (fr) 1976-02-06
FR2281374A1 (fr) 1976-03-05
NL7509364A (nl) 1976-02-10
FR2281374B1 (zh) 1979-10-05
CH619962A5 (en) 1980-10-31
LU73149A1 (zh) 1977-04-13
GB1523481A (en) 1978-08-31
IT1044019B (it) 1980-02-29
IE41442B1 (en) 1980-01-02

Similar Documents

Publication Publication Date Title
US4159988A (en) Synthetic phospholipids, a process for their manufacture and their use
Yuan et al. Synthesis and evaluation of phospholipid analogs as inhibitors of cobra venom phospholipase A2
Eibl et al. Synthesis of enantiomerically pure glyceryl esters and ethers. I. Methods employing the precursor 1, 2-isopropylidene-sn-glycerol
CA2812178C (en) Methods for the synthesis of plasmalogens and plasmalogen derivatives, and therapeutic uses thereof
US4873355A (en) Process for regioselectively preparing phosphorylated inositols and other cyclitols
IE911267A1 (en) 2(5h)-furanones substituted in the 5 and or in the 4¹position, as anti-inflammatory agents
EP0036583A2 (de) Glycerin-3-phosphorsäurehalogenalkylester und Verfahren zu ihrer Herstellung und Weiterverarbeitung
CA1063615A (en) Synthetic phospholipids, a process for their manufacture and their use
US4163748A (en) Propane-1,3-diol phosphatides and method of preparing the same
Baer et al. Synthesis of unsaturated α-phosphatidic acids and α-bisphosphatidic acids. Cardiolipin substitutes. IV
CA1063131A (en) Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use
JPS59501211A (ja) 燐脂質合成用の新規グリセリン誘導体
US4160773A (en) Synthetic alkyl esters of phospholipid acid, structural analogs thereof and a process for their manufacture and their use
US5081147A (en) 4-(1-hydroxy-2-substituted amino)ethyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents
US4751320A (en) Phosphoric ester and process for producing same
US3632692A (en) Organophosphorus anhydrides
GB1581810A (en) Process for the preparation of phospholipids
JP4677550B2 (ja) 環状エステル化合物
Liu et al. Synthesis of novel chiral 2‐oxo‐and 2‐thio‐1, 3, 2‐oxazaphospholidines via asymmetric cyclization of l‐methionol with (thio) phosphoryl dichlorides
EP0043472B1 (en) 3-hydrocarbylthio-2-acyloxypropyl 2-trimethylammonioethyl phosphates, process for producing the same and pharmaceutical preparations containing the same
Massing et al. Synthesis of enantiomerically pure 1-O-phosphocholine-2-O-acyl-octadecane and 1-O-phosphocholine-2-N-acyl-octadecane
EP0372941A2 (en) Anti-inflammatory 5-hydroxy-2-furanones
US4740609A (en) Phosphoric esters and process for preparing same
Garcia et al. Synthesis of new ether glycerophospholipids structurally related to modulator
Thompson Enol and acyl phosphates as intermediates in the synthesis of nonrandom triglycerides