GB1523481A - Synthetic aliphatic hydrocarbon esters of phospholipid acids structural analogues thereof and a process for their manufacture and their use - Google Patents
Synthetic aliphatic hydrocarbon esters of phospholipid acids structural analogues thereof and a process for their manufacture and their useInfo
- Publication number
- GB1523481A GB1523481A GB32665/75A GB3266575A GB1523481A GB 1523481 A GB1523481 A GB 1523481A GB 32665/75 A GB32665/75 A GB 32665/75A GB 3266575 A GB3266575 A GB 3266575A GB 1523481 A GB1523481 A GB 1523481A
- Authority
- GB
- United Kingdom
- Prior art keywords
- structural analogues
- manufacture
- aliphatic hydrocarbon
- reacting
- naturally occurring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 aliphatic hydrocarbon esters Chemical class 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000008103 phosphatidic acids Chemical class 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011538 cleaning material Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000865 phosphorylative effect Effects 0.000 abstract 1
- 150000003138 primary alcohols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
Abstract
Synthetic alkyl esters of phosphatidic acids which correspond to naturally occurring phospholipids and can be used instead of them, where the phosphatidic acids have the accompanying formulae III and IV, in which the symbols R1, R2 and R3 have the meanings given in Patent Claim 1, and their structural analogues listed in Patent Claim 1 under a) to f) are prepared by A) reacting a primary alcohol of formula I R3-OH (I> with phosphorus oxychloride in the presence of an inert organic solvent; and B) reacting the resulting phosphorylating agent of the formula II <IMAGE> with a suitable polyhydroxy compound in which one hydroxyl group is in free form and the remaining ones are protected. Elimination of the group R1-CO- or R2-CO- gives the corresponding lyso compounds from the compounds of the formulae III and IV. The products of the process can be employed instead of naturally occurring phospholipids and are particularly suitable as emulsifiers for the preparation of detergents and cleaning materials and as additives to foodstuffs and cosmetics. <IMAGE>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2437833A DE2437833A1 (en) | 1974-08-06 | 1974-08-06 | SYNTHETIC ALKYLESTERS OF PHOSPHATIC ACID AND STRUCTURAL ANALOGA, PROCESS FOR THEIR PRODUCTION AND USE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1523481A true GB1523481A (en) | 1978-08-31 |
Family
ID=5922579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32665/75A Expired GB1523481A (en) | 1974-08-06 | 1975-08-05 | Synthetic aliphatic hydrocarbon esters of phospholipid acids structural analogues thereof and a process for their manufacture and their use |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5143724A (en) |
| AU (1) | AU8368575A (en) |
| BE (1) | BE832181A (en) |
| CA (1) | CA1063131A (en) |
| CH (1) | CH619962A5 (en) |
| DE (1) | DE2437833A1 (en) |
| DK (1) | DK355675A (en) |
| FR (1) | FR2281374A1 (en) |
| GB (1) | GB1523481A (en) |
| IE (1) | IE41442B1 (en) |
| IT (1) | IT1044019B (en) |
| LU (1) | LU73149A1 (en) |
| NL (1) | NL7509364A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56677Y2 (en) * | 1976-12-27 | 1981-01-09 | ||
| US4783402A (en) * | 1983-04-11 | 1988-11-08 | Meito Sangyo Kabushiki Kaisha | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2750399A (en) * | 1949-12-27 | 1956-06-12 | Monsanto Chemicals | Process for alkyl phosphoryl dichlorides |
-
1974
- 1974-08-06 DE DE2437833A patent/DE2437833A1/en not_active Withdrawn
-
1975
- 1975-08-04 IT IT26085/75A patent/IT1044019B/en active
- 1975-08-05 GB GB32665/75A patent/GB1523481A/en not_active Expired
- 1975-08-05 IE IE1732/75A patent/IE41442B1/en unknown
- 1975-08-05 AU AU83685/75A patent/AU8368575A/en not_active Expired
- 1975-08-05 CA CA232,800A patent/CA1063131A/en not_active Expired
- 1975-08-05 DK DK355675A patent/DK355675A/en unknown
- 1975-08-05 LU LU73149A patent/LU73149A1/xx unknown
- 1975-08-06 CH CH1028475A patent/CH619962A5/en not_active IP Right Cessation
- 1975-08-06 JP JP50095096A patent/JPS5143724A/en active Pending
- 1975-08-06 NL NL7509364A patent/NL7509364A/en not_active Application Discontinuation
- 1975-08-06 FR FR7524488A patent/FR2281374A1/en active Granted
- 1975-08-06 BE BE158988A patent/BE832181A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1063131A (en) | 1979-09-25 |
| CH619962A5 (en) | 1980-10-31 |
| FR2281374A1 (en) | 1976-03-05 |
| FR2281374B1 (en) | 1979-10-05 |
| JPS5143724A (en) | 1976-04-14 |
| BE832181A (en) | 1976-02-06 |
| DK355675A (en) | 1976-02-07 |
| IT1044019B (en) | 1980-02-29 |
| AU8368575A (en) | 1977-02-10 |
| LU73149A1 (en) | 1977-04-13 |
| DE2437833A1 (en) | 1976-02-26 |
| NL7509364A (en) | 1976-02-10 |
| IE41442L (en) | 1976-02-06 |
| IE41442B1 (en) | 1980-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |