IE41442L - Esters of phospholipid acids - Google Patents
Esters of phospholipid acidsInfo
- Publication number
- IE41442L IE41442L IE751732A IE173275A IE41442L IE 41442 L IE41442 L IE 41442L IE 751732 A IE751732 A IE 751732A IE 173275 A IE173275 A IE 173275A IE 41442 L IE41442 L IE 41442L
- Authority
- IE
- Ireland
- Prior art keywords
- reacting
- naturally occurring
- formula
- image
- compounds
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000002148 esters Chemical class 0.000 title 1
- -1 phospholipid acids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000008103 phosphatidic acids Chemical class 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011538 cleaning material Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000000865 phosphorylative effect Effects 0.000 abstract 1
- 150000003138 primary alcohols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
Abstract
Synthetic alkyl esters of phosphatidic acids which correspond to naturally occurring phospholipids and can be used instead of them, where the phosphatidic acids have the accompanying formulae III and IV, in which the symbols R1, R2 and R3 have the meanings given in Patent Claim 1, and their structural analogues listed in Patent Claim 1 under a) to f) are prepared by A) reacting a primary alcohol of formula I R3-OH (I> with phosphorus oxychloride in the presence of an inert organic solvent; and B) reacting the resulting phosphorylating agent of the formula II <IMAGE> with a suitable polyhydroxy compound in which one hydroxyl group is in free form and the remaining ones are protected. Elimination of the group R1-CO- or R2-CO- gives the corresponding lyso compounds from the compounds of the formulae III and IV. The products of the process can be employed instead of naturally occurring phospholipids and are particularly suitable as emulsifiers for the preparation of detergents and cleaning materials and as additives to foodstuffs and cosmetics. <IMAGE>
[GB1523481A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2437833A DE2437833A1 (en) | 1974-08-06 | 1974-08-06 | SYNTHETIC ALKYLESTERS OF PHOSPHATIC ACID AND STRUCTURAL ANALOGA, PROCESS FOR THEIR PRODUCTION AND USE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41442L true IE41442L (en) | 1976-02-06 |
| IE41442B1 IE41442B1 (en) | 1980-01-02 |
Family
ID=5922579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1732/75A IE41442B1 (en) | 1974-08-06 | 1975-08-05 | Synthetic aliphatic hydrocarbon esters of phospholipid acids structural analogues thereof and a process for their manufacture and their use |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5143724A (en) |
| AU (1) | AU8368575A (en) |
| BE (1) | BE832181A (en) |
| CA (1) | CA1063131A (en) |
| CH (1) | CH619962A5 (en) |
| DE (1) | DE2437833A1 (en) |
| DK (1) | DK355675A (en) |
| FR (1) | FR2281374A1 (en) |
| GB (1) | GB1523481A (en) |
| IE (1) | IE41442B1 (en) |
| IT (1) | IT1044019B (en) |
| LU (1) | LU73149A1 (en) |
| NL (1) | NL7509364A (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56677Y2 (en) * | 1976-12-27 | 1981-01-09 | ||
| US4783402A (en) * | 1983-04-11 | 1988-11-08 | Meito Sangyo Kabushiki Kaisha | Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2750399A (en) * | 1949-12-27 | 1956-06-12 | Monsanto Chemicals | Process for alkyl phosphoryl dichlorides |
-
1974
- 1974-08-06 DE DE2437833A patent/DE2437833A1/en not_active Withdrawn
-
1975
- 1975-08-04 IT IT26085/75A patent/IT1044019B/en active
- 1975-08-05 LU LU73149A patent/LU73149A1/xx unknown
- 1975-08-05 DK DK355675A patent/DK355675A/en unknown
- 1975-08-05 IE IE1732/75A patent/IE41442B1/en unknown
- 1975-08-05 AU AU83685/75A patent/AU8368575A/en not_active Expired
- 1975-08-05 CA CA232,800A patent/CA1063131A/en not_active Expired
- 1975-08-05 GB GB32665/75A patent/GB1523481A/en not_active Expired
- 1975-08-06 FR FR7524488A patent/FR2281374A1/en active Granted
- 1975-08-06 JP JP50095096A patent/JPS5143724A/en active Pending
- 1975-08-06 BE BE158988A patent/BE832181A/en not_active IP Right Cessation
- 1975-08-06 CH CH1028475A patent/CH619962A5/en not_active IP Right Cessation
- 1975-08-06 NL NL7509364A patent/NL7509364A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK355675A (en) | 1976-02-07 |
| FR2281374A1 (en) | 1976-03-05 |
| BE832181A (en) | 1976-02-06 |
| IE41442B1 (en) | 1980-01-02 |
| AU8368575A (en) | 1977-02-10 |
| GB1523481A (en) | 1978-08-31 |
| DE2437833A1 (en) | 1976-02-26 |
| NL7509364A (en) | 1976-02-10 |
| CH619962A5 (en) | 1980-10-31 |
| CA1063131A (en) | 1979-09-25 |
| JPS5143724A (en) | 1976-04-14 |
| IT1044019B (en) | 1980-02-29 |
| FR2281374B1 (en) | 1979-10-05 |
| LU73149A1 (en) | 1977-04-13 |
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