CA1062280A - Procede de preparation de clofibrate de metformine - Google Patents

Procede de preparation de clofibrate de metformine

Info

Publication number
CA1062280A
CA1062280A CA222,798A CA222798A CA1062280A CA 1062280 A CA1062280 A CA 1062280A CA 222798 A CA222798 A CA 222798A CA 1062280 A CA1062280 A CA 1062280A
Authority
CA
Canada
Prior art keywords
metformin
clofibrate
salt
acid
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA222,798A
Other languages
English (en)
French (fr)
Other versions
CA222798S (en
Inventor
Claude Bohuon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Original Assignee
D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D'etudes Et D'exploitation De Marques Et Brevets Sems Ste filed Critical D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Application granted granted Critical
Publication of CA1062280A publication Critical patent/CA1062280A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA222,798A 1974-03-22 1975-03-21 Procede de preparation de clofibrate de metformine Expired CA1062280A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7409963A FR2264525B1 (de) 1974-03-22 1974-03-22

Publications (1)

Publication Number Publication Date
CA1062280A true CA1062280A (fr) 1979-09-11

Family

ID=9136732

Family Applications (1)

Application Number Title Priority Date Filing Date
CA222,798A Expired CA1062280A (fr) 1974-03-22 1975-03-21 Procede de preparation de clofibrate de metformine

Country Status (11)

Country Link
JP (1) JPS5526134B2 (de)
AT (1) AT346856B (de)
BE (1) BE826999A (de)
CA (1) CA1062280A (de)
CH (1) CH609669A5 (de)
DE (1) DE2511576C2 (de)
ES (1) ES435898A1 (de)
FR (1) FR2264525B1 (de)
GB (1) GB1462316A (de)
LU (1) LU72102A1 (de)
NL (1) NL169461C (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60196425A (ja) * 1984-03-16 1985-10-04 Daido Metal Kogyo Kk 軸受すきまを一定に維持されたパツド型ジヤ−ナル軸受装置
FR2774591B1 (fr) * 1998-02-12 2000-05-05 Lipha Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
FR2796551B1 (fr) * 1999-07-23 2003-07-25 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940B1 (fr) * 1999-07-26 2005-04-08 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7116M (de) * 1968-01-08 1969-07-15
AT317235B (de) * 1972-08-22 1974-08-26 Hurka Wilhelm Verfahren zur Herstellung des neuen 2-(p-Chlorphenoxy)-2-methylpropionsäuresalzes des 1-Phenäthylbiguanids

Also Published As

Publication number Publication date
NL7503515A (nl) 1975-09-24
GB1462316A (en) 1977-01-26
FR2264525A1 (de) 1975-10-17
DE2511576A1 (de) 1975-09-25
NL169461B (nl) 1982-02-16
ES435898A1 (es) 1976-12-16
CH609669A5 (en) 1979-03-15
DE2511576C2 (de) 1983-07-07
FR2264525B1 (de) 1977-11-04
NL169461C (nl) 1982-07-16
LU72102A1 (de) 1975-08-20
ATA217875A (de) 1978-04-15
JPS5526134B2 (de) 1980-07-11
BE826999A (fr) 1975-07-16
JPS50135043A (de) 1975-10-25
AT346856B (de) 1978-11-27

Similar Documents

Publication Publication Date Title
FR2658513A1 (fr) Procede de preparation de l'acide cis-beta-phenylglycidique-(2r,3r).
JPH01503786A (ja) プロスタグランジン誘導体，それらの製法及びそれらを含有する医薬組成物
CA1062280A (fr) Procede de preparation de clofibrate de metformine
EP0349432B1 (de) Strontiumsalz, Verfahren zu dessen Herstellung und Arzneimittel, die es enthalten
JPH0231704B2 (de)
WO2008053325A1 (en) A salt of 3-benzyl-2-methyl-2,3,3a,4,5,6,7,7a-octahydrobenzo[d]isoxazol-4-one
FR2638744A1 (fr) Acide 1,2,3,4-tetrahydroisoquinoleine-3-carboxylique, ses precurseurs et leur preparation
KR20020091077A (ko) α-(2-4-디술포페닐)-Ｎ-ｔｅｒｔ-부틸니트론 및 제약상허용되는 그의 염의 신규 제조 방법
JPH11228512A (ja) Ｄ−アロイソロイシンの製造方法および製造の中間体
HU229518B1 (hu) Eljárás 13-cisz-retinsav elõállítására
FR2566769A1 (fr) Agent de fluoration de composes organiques notamment de composes acetyleniques, leur procede de preparation et leur utilisation dans les reactions d'addition ou de substitution nucleophile
DE60007599T2 (de) Verfahren zur Herstellung von zyklischen Piperidinylaminomethyl-trifluoromethyl-etherderivaten
CH680733A5 (de)
FR2537132A1 (fr) Nouveaux derives soufres de 2-amino-1-phenyl-1-ethanol, utilisation en therapeutique et procede de preparation
EP0170937B1 (de) Doppelsalz von Desoxyfructosyl-Serotonin und von Kreatinin, seine Herstellung und pharmazeutische Zusammensetzungen,die es enthalten
JP3924027B2 (ja) オルソヒドロキシマンデル酸ナトリウム／フエノール／水錯体、その製造法及びオルソヒドロキシマンデル酸ナトリウムの分離のための使用
FR2464952A1 (fr) Nouveaux derives thienyliques, leur procede de preparation et leur application comme medicaments
FR2491471A1 (fr) Benzoxazolinones substituees, leur preparation et leur application en therapeutique
KR20020091078A (ko) α-(2-4-디술포페닐)-Ｎ-ｔｅｒｔ-부틸니트론 및 제약상허용되는 그의 염의 신규 제조 방법
BE635463A (de)
BE903568A (fr) Nouveaux composes chimiques a activites antiphlogistiques, antiseptiques et detergentes
EP0110748A1 (de) Phenyl-(3-aminopropyl)-keton-derivate, ihre therapeutische Verwendung und Verfahren zu ihrer Herstellung
CH400177A (fr) Procédé de préparation d'alcaloïdes
BE837320A (fr) Derives ethers de 3-amino-1,2-propanodiol
FR2738567A1 (fr) Derives de alpha-phenylpiperidine-1-propanol, leur preparation et leur application en therapeutique