CA1062280A - Procede de preparation de clofibrate de metformine - Google Patents

Procede de preparation de clofibrate de metformine

Info

Publication number
CA1062280A
CA1062280A CA222,798A CA222798A CA1062280A CA 1062280 A CA1062280 A CA 1062280A CA 222798 A CA222798 A CA 222798A CA 1062280 A CA1062280 A CA 1062280A
Authority
CA
Canada
Prior art keywords
metformin
clofibrate
salt
acid
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA222,798A
Other languages
English (en)
French (fr)
Other versions
CA222798S (en
Inventor
Claude Bohuon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Original Assignee
D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D'etudes Et D'exploitation De Marques Et Brevets Sems Ste filed Critical D'etudes Et D'exploitation De Marques Et Brevets Sems Ste
Application granted granted Critical
Publication of CA1062280A publication Critical patent/CA1062280A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA222,798A 1974-03-22 1975-03-21 Procede de preparation de clofibrate de metformine Expired CA1062280A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7409963A FR2264525B1 (de) 1974-03-22 1974-03-22

Publications (1)

Publication Number Publication Date
CA1062280A true CA1062280A (fr) 1979-09-11

Family

ID=9136732

Family Applications (1)

Application Number Title Priority Date Filing Date
CA222,798A Expired CA1062280A (fr) 1974-03-22 1975-03-21 Procede de preparation de clofibrate de metformine

Country Status (11)

Country Link
JP (1) JPS5526134B2 (de)
AT (1) AT346856B (de)
BE (1) BE826999A (de)
CA (1) CA1062280A (de)
CH (1) CH609669A5 (de)
DE (1) DE2511576C2 (de)
ES (1) ES435898A1 (de)
FR (1) FR2264525B1 (de)
GB (1) GB1462316A (de)
LU (1) LU72102A1 (de)
NL (1) NL169461C (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60196425A (ja) * 1984-03-16 1985-10-04 Daido Metal Kogyo Kk 軸受すきまを一定に維持されたパツド型ジヤ−ナル軸受装置
FR2774591B1 (fr) * 1998-02-12 2000-05-05 Lipha Composition pharmaceutique comprenant l'association metformine et fibrate et son utilisation pour la preparation de medicaments destines a reduire l'hyperglycemie
FR2796551B1 (fr) * 1999-07-23 2003-07-25 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940B1 (fr) * 1999-07-26 2005-04-08 Lipha Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7116M (de) * 1968-01-08 1969-07-15
AT317235B (de) * 1972-08-22 1974-08-26 Hurka Wilhelm Verfahren zur Herstellung des neuen 2-(p-Chlorphenoxy)-2-methylpropionsäuresalzes des 1-Phenäthylbiguanids

Also Published As

Publication number Publication date
DE2511576A1 (de) 1975-09-25
BE826999A (fr) 1975-07-16
ATA217875A (de) 1978-04-15
DE2511576C2 (de) 1983-07-07
FR2264525A1 (de) 1975-10-17
NL169461B (nl) 1982-02-16
AT346856B (de) 1978-11-27
ES435898A1 (es) 1976-12-16
JPS50135043A (de) 1975-10-25
JPS5526134B2 (de) 1980-07-11
GB1462316A (en) 1977-01-26
FR2264525B1 (de) 1977-11-04
LU72102A1 (de) 1975-08-20
NL7503515A (nl) 1975-09-24
NL169461C (nl) 1982-07-16
CH609669A5 (en) 1979-03-15

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