CA1058610A - 17a, 21-diesters of the pregnane series - Google Patents
17a, 21-diesters of the pregnane seriesInfo
- Publication number
- CA1058610A CA1058610A CA232,579A CA232579A CA1058610A CA 1058610 A CA1058610 A CA 1058610A CA 232579 A CA232579 A CA 232579A CA 1058610 A CA1058610 A CA 1058610A
- Authority
- CA
- Canada
- Prior art keywords
- formula
- group
- beta
- compound
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB33786/74A GB1516095A (en) | 1974-07-31 | 1974-07-31 | 17,21-diesters of 17alpha,21-dihydroxy-steroids of the pregnane series |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1058610A true CA1058610A (en) | 1979-07-17 |
Family
ID=10357423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA232,579A Expired CA1058610A (en) | 1974-07-31 | 1975-07-30 | 17a, 21-diesters of the pregnane series |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS51125059A (xx) |
| BE (1) | BE831931A (xx) |
| CA (1) | CA1058610A (xx) |
| CH (1) | CH615442A5 (xx) |
| DE (1) | DE2534051A1 (xx) |
| DK (1) | DK139303B (xx) |
| ES (1) | ES439852A1 (xx) |
| FR (1) | FR2280383A1 (xx) |
| GB (1) | GB1516095A (xx) |
| IE (1) | IE42124B1 (xx) |
| NL (1) | NL7509075A (xx) |
| SE (1) | SE7508654L (xx) |
| ZA (1) | ZA754907B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456602A (en) * | 1982-08-23 | 1984-06-26 | The Upjohn Company | Amine containing ester prodrugs of corticosteroids |
| US4443440A (en) * | 1982-08-30 | 1984-04-17 | The Upjohn Company | Amine containing ester prodrugs of corticosteroids |
| FR2600653B1 (fr) * | 1986-06-24 | 1988-12-16 | Pasteur Strasbourg Universite | Composes de synthese associative d'acides amines soufres ou non soufres avec des derives du d-4 pregnene 3,20-dione ou avec des derives du d-1,4 pregnadiene 3,20-dione aux proprietes glucocorticoides et anti-inflammatoires, procedes d'obtention, compositions pharmaceutiques les contenant. proprietes pharmacologiques et applications |
| DE4333920A1 (de) | 1993-10-05 | 1995-04-13 | Hoechst Ag | Corticoid-17,21-dicarbonsäureester sowie Corticosteroid-17-carbonsäureester-21-kohlensäureester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1044212B (it) * | 1971-03-17 | 1980-03-20 | Sigma Tau Ind Farmaceuti | Esteri del besametazone e betametazone |
| GB1440063A (en) * | 1972-08-11 | 1976-06-23 | Glaxo Lab Ltd | 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids |
-
1974
- 1974-07-31 GB GB33786/74A patent/GB1516095A/en not_active Expired
-
1975
- 1975-07-30 DK DK346975AA patent/DK139303B/da unknown
- 1975-07-30 ES ES439852A patent/ES439852A1/es not_active Expired
- 1975-07-30 IE IE1708/75A patent/IE42124B1/en unknown
- 1975-07-30 ZA ZA00754907A patent/ZA754907B/xx unknown
- 1975-07-30 NL NL7509075A patent/NL7509075A/xx not_active Application Discontinuation
- 1975-07-30 FR FR7523787A patent/FR2280383A1/fr active Granted
- 1975-07-30 BE BE158780A patent/BE831931A/xx unknown
- 1975-07-30 SE SE7508654A patent/SE7508654L/xx unknown
- 1975-07-30 JP JP50092137A patent/JPS51125059A/ja active Pending
- 1975-07-30 CH CH996575A patent/CH615442A5/de not_active IP Right Cessation
- 1975-07-30 DE DE19752534051 patent/DE2534051A1/de not_active Withdrawn
- 1975-07-30 CA CA232,579A patent/CA1058610A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK346975A (xx) | 1976-02-01 |
| IE42124L (en) | 1976-01-31 |
| NL7509075A (nl) | 1976-02-03 |
| FR2280383A1 (fr) | 1976-02-27 |
| ZA754907B (en) | 1976-07-28 |
| SE7508654L (sv) | 1976-02-02 |
| CH615442A5 (en) | 1980-01-31 |
| DE2534051A1 (de) | 1976-02-19 |
| DK139303B (da) | 1979-01-29 |
| ES439852A1 (es) | 1977-03-01 |
| JPS51125059A (en) | 1976-11-01 |
| FR2280383B1 (xx) | 1978-10-06 |
| IE42124B1 (en) | 1980-06-04 |
| DK139303C (xx) | 1979-08-06 |
| BE831931A (fr) | 1976-01-30 |
| GB1516095A (en) | 1978-06-28 |
| AU8353175A (en) | 1977-02-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3856828A (en) | Anti-inflammatory steroids of the androstane series having a halo-substituted c{11 {14 c{11 {11 alkoxy carbonyl group at the 17{62 {0 position | |
| US2736734A (en) | delta1,4-3,20-diketo-11-oxygenated-17,21-dihydroxy-pregnadiene 21-tertiary butyl acetates and 9-fluoro derivatives thereof | |
| US3780177A (en) | 17-butyrate,21-ester derivatives of 6alpha,9alpha-difluoroprednisolone,compositions and use | |
| US4996318A (en) | Amino-9,10-secosteroids useful for treating head injury, spinal cord trauma or stroke | |
| PL121469B1 (en) | Process for preparing novel derivatives of thioethianic acidsloty | |
| US3721687A (en) | 3-keto-delta 4-9alpha-halo-11-oxygenated-16-methyl or methylene-17alpha-acyloxy-20-keto-21-halo pregnenes | |
| JPH06199887A (ja) | 新規なエリスロマイシン誘導体、それらの製造法及びそれらの薬剤としての用途 | |
| JPH08508278A (ja) | 新規プレドニソロン誘導体 | |
| HU186965B (en) | Process for producing new 6-alpha-methyl-prednisolone derivatives | |
| US3868380A (en) | Diphenylyl-al kanoylaminopyridines and salts thereof | |
| US3318926A (en) | 7alpha-methyl-16alpha-hydroxy-estrones | |
| CA1058610A (en) | 17a, 21-diesters of the pregnane series | |
| US5599807A (en) | Steroid derivatives | |
| US4213984A (en) | 11-(Piperazino-acetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones and salts thereof | |
| WO1987007895A1 (en) | Androstane-type and cortical aminoesters | |
| US4069322A (en) | Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids | |
| US4427671A (en) | Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments | |
| EP0072989A1 (de) | Neue Kortikoide ihre Herstellung und Verwendung | |
| US4331663A (en) | 4α,5α-Epoxy-3,20-dioxopregnane-2α,16α-dicarbonitrile and intermediates and process for preparation, method of use and compositions thereof | |
| GB2232890A (en) | Use of steroidal compounds as anti-fungal agents | |
| JPS6044320B2 (ja) | ステロイド性９，１１β−ジハロ−〔１６α，１７−ｂ〕〔１，４〕ジオキサン類の製造法 | |
| US3329570A (en) | Therapeutic compositions comprising 21-dicyclohexylmethyl carbonate esters of pregnane derivatives | |
| EP0116329A1 (de) | Neue D-Homosteroide, deren Herstellung und pharmazeutische Präparate | |
| JPS60139697A (ja) | ヒドロコーチゾン誘導体、その製法及びコルチコイド製剤 | |
| US3783149A (en) | {60 -l talomethylosides of certain genins of the cardenolide and bufadienolide series |