CA1058194A - Substituted benzenedisulfonamides as anthelmintics - Google Patents

Substituted benzenedisulfonamides as anthelmintics

Info

Publication number
CA1058194A
CA1058194A CA241,261A CA241261A CA1058194A CA 1058194 A CA1058194 A CA 1058194A CA 241261 A CA241261 A CA 241261A CA 1058194 A CA1058194 A CA 1058194A
Authority
CA
Canada
Prior art keywords
compound
amino
formula
trichlorovinyl
benzenedisulfonamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA241,261A
Other languages
English (en)
French (fr)
Inventor
Helmut H. Mrozik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/616,331 external-priority patent/US4064239A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1058194A publication Critical patent/CA1058194A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/013—Preparation of halogenated hydrocarbons by addition of halogens
    • C07C17/04—Preparation of halogenated hydrocarbons by addition of halogens to unsaturated halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2637—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions between a compound containing only oxygen and possibly halogen as hetero-atoms and a halogenated hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA241,261A 1974-12-16 1975-12-08 Substituted benzenedisulfonamides as anthelmintics Expired CA1058194A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53335274A 1974-12-16 1974-12-16
US05/616,331 US4064239A (en) 1974-12-16 1975-09-26 Halogenated unsaturated alkyl benzenedisulfonamides as anthelmintics

Publications (1)

Publication Number Publication Date
CA1058194A true CA1058194A (en) 1979-07-10

Family

ID=27064157

Family Applications (1)

Application Number Title Priority Date Filing Date
CA241,261A Expired CA1058194A (en) 1974-12-16 1975-12-08 Substituted benzenedisulfonamides as anthelmintics

Country Status (16)

Country Link
AR (1) AR218216A1 (xx)
CA (1) CA1058194A (xx)
DE (1) DE2556122C2 (xx)
DK (1) DK145756C (xx)
FI (1) FI64799C (xx)
FR (1) FR2294710A1 (xx)
GB (1) GB1485897A (xx)
IE (1) IE42203B1 (xx)
IL (1) IL48610A (xx)
LU (1) LU74019A1 (xx)
NL (2) NL187394C (xx)
NO (1) NO142667C (xx)
NZ (1) NZ179477A (xx)
OA (1) OA05183A (xx)
PH (1) PH12041A (xx)
SE (1) SE426817B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107868024A (zh) * 2017-10-25 2018-04-03 浙江海正药业股份有限公司 克洛索隆的晶型及其制备方法和用途
CN113773235B (zh) * 2021-08-20 2022-06-17 北大方正集团有限公司 一种氯舒隆的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1483222A (fr) * 1965-06-24 1967-06-02 Merck & Co Inc Production de nouveaux dérivés, substitués à l'azote, de la 5-chloro-2, 4-disulfamoylaniline
SE410598B (sv) * 1973-05-11 1979-10-22 Merck & Co Inc Forfarande for framstellning av bensendisulfonamider med anthelmintisk verkan

Also Published As

Publication number Publication date
SE7513569L (sv) 1976-06-17
FI64799C (fi) 1984-01-10
DK145756B (da) 1983-02-21
DK544775A (da) 1976-06-17
DE2556122C2 (de) 1986-05-22
IE42203L (en) 1976-06-16
FR2294710B1 (xx) 1979-09-21
NL7514163A (nl) 1976-06-18
OA05183A (fr) 1981-01-31
AU8743575A (en) 1977-06-16
NO142667B (no) 1980-06-16
PH12041A (en) 1978-10-16
DE2556122A1 (de) 1976-06-24
IE42203B1 (en) 1980-06-18
IL48610A0 (en) 1976-02-29
LU74019A1 (xx) 1976-11-11
FI753392A (xx) 1976-06-17
SE426817B (sv) 1983-02-14
NZ179477A (en) 1978-04-03
FR2294710A1 (fr) 1976-07-16
NL930115I1 (nl) 1993-10-18
DK145756C (da) 1983-08-08
GB1485897A (en) 1977-09-14
NL187394B (nl) 1991-04-16
AR218216A1 (es) 1980-05-30
NO142667C (no) 1980-09-24
NL187394C (nl) 1991-09-16
IL48610A (en) 1979-10-31
FI64799B (fi) 1983-09-30
NO754087L (xx) 1976-06-17

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