CA1034525A - Production of cephalosporins with bound penicillinacylase - Google Patents

Production of cephalosporins with bound penicillinacylase

Info

Publication number
CA1034525A
CA1034525A CA212,324A CA212324A CA1034525A CA 1034525 A CA1034525 A CA 1034525A CA 212324 A CA212324 A CA 212324A CA 1034525 A CA1034525 A CA 1034525A
Authority
CA
Canada
Prior art keywords
penicillinacylase
cephalosporins
bound
production
bound penicillinacylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA212,324A
Other languages
English (en)
French (fr)
Other versions
CA212324S (en
Inventor
Carl Kutzbach
Uwe Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA1034525A publication Critical patent/CA1034525A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087—Acrylic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyamides (AREA)
CA212,324A 1973-11-03 1974-10-25 Production of cephalosporins with bound penicillinacylase Expired CA1034525A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732355078 DE2355078A1 (de) 1973-11-03 1973-11-03 Verfahren zur herstellung von 7-amino-delta hoch 3-cephem-derivaten

Publications (1)

Publication Number Publication Date
CA1034525A true CA1034525A (en) 1978-07-11

Family

ID=5897177

Family Applications (1)

Application Number Title Priority Date Filing Date
CA212,324A Expired CA1034525A (en) 1973-11-03 1974-10-25 Production of cephalosporins with bound penicillinacylase

Country Status (26)

Country Link
US (1) US3930949A (cs)
JP (1) JPS5721994B2 (cs)
AT (1) AT337355B (cs)
BE (1) BE821760A (cs)
CA (1) CA1034525A (cs)
CH (1) CH607772A5 (cs)
CS (1) CS182274B2 (cs)
DD (1) DD115124A5 (cs)
DE (1) DE2355078A1 (cs)
DK (1) DK571674A (cs)
EG (1) EG11318A (cs)
ES (1) ES431588A1 (cs)
FI (1) FI320574A (cs)
FR (1) FR2249889B1 (cs)
GB (1) GB1448419A (cs)
HK (1) HK64479A (cs)
HU (1) HU169827B (cs)
IE (1) IE40248B1 (cs)
IL (1) IL45973A (cs)
IN (1) IN138712B (cs)
LU (1) LU71224A1 (cs)
NL (1) NL7414302A (cs)
NO (1) NO743770L (cs)
SE (1) SE413598B (cs)
SU (1) SU622408A3 (cs)
ZA (1) ZA747033B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5619999B2 (cs) * 1974-02-07 1981-05-11
JPS50123885A (cs) * 1974-03-15 1975-09-29
US4282322A (en) * 1975-11-24 1981-08-04 Merck & Co., Inc. Process for enzymatic deacylation of antibiotics
JPS52143289A (en) * 1976-05-24 1977-11-29 Meiji Seika Kaisha Ltd Production of 7-amino-cephem derivatives by filamentous fungi
DE3432060A1 (de) * 1984-08-31 1986-03-06 Bayer Ag, 5090 Leverkusen Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren
US4981789A (en) * 1987-03-18 1991-01-01 Merck & Co., Inc. One-step enzymatic conversion of cephalosporin C and derivatives to 7-aminocephalosporanic acid and derivatives
US5104800A (en) * 1989-06-27 1992-04-14 Merck & Co., Inc. One-step cephalosporin c amidase enzyme
US5229274A (en) * 1989-06-27 1993-07-20 Merck & Co., Inc. Gene encoding one step cephalosporin C amidase and expression thereof in recombinant bacillus
DE4030040A1 (de) * 1990-09-22 1992-03-26 Bayer Ag Enzymatische de-acylierung von acyl-aminosorbosen und dessen verwendung bei der herstellung von 1-desoxynojirimicin
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
JP2002316991A (ja) * 2001-04-18 2002-10-31 Otsuka Chem Co Ltd ペニシリン及びセファロスポリン化合物
US20080066773A1 (en) * 2006-04-21 2008-03-20 Anderson Daniel G In situ polymerization for hair treatment
CN103060417B (zh) * 2011-10-19 2014-08-27 广州白云山制药股份有限公司广州白云山化学制药厂 7-氨基-3-乙烯基-8-氧代-5-硫杂-1-氮杂双环［4.2.0］辛-2-烯-2-羧酸的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3239394A (en) * 1964-06-15 1966-03-08 Merck & Co Inc Process for producing 7-amino-cephalosporanic acid
US3507861A (en) * 1966-09-14 1970-04-21 Lilly Co Eli Certain 3-methyl-cephalosporin compounds
US3736230A (en) * 1969-02-17 1973-05-29 P Delin Process for producing 6-amino-penicillanic acid
GB1473100A (cs) * 1973-05-10 1977-05-11

Also Published As

Publication number Publication date
ZA747033B (en) 1975-11-26
SU622408A3 (ru) 1978-08-30
IE40248L (en) 1975-05-03
CS182274B2 (en) 1978-04-28
IL45973A (en) 1977-05-31
IL45973A0 (en) 1975-02-10
HU169827B (cs) 1977-02-28
AU7491974A (en) 1976-05-06
LU71224A1 (cs) 1975-06-24
DE2355078A1 (de) 1975-05-07
CH607772A5 (cs) 1978-10-31
US3930949A (en) 1976-01-06
BE821760A (fr) 1975-04-30
SE413598B (sv) 1980-06-09
NL7414302A (nl) 1975-05-07
DD115124A5 (cs) 1975-09-12
IE40248B1 (en) 1979-04-11
FR2249889B1 (cs) 1979-02-23
SE7413734L (cs) 1975-05-05
ATA877974A (de) 1976-10-15
NO743770L (cs) 1975-06-02
ES431588A1 (es) 1977-02-16
JPS5721994B2 (cs) 1982-05-11
HK64479A (en) 1979-09-14
EG11318A (en) 1977-08-15
FI320574A (cs) 1975-05-04
FR2249889A1 (cs) 1975-05-30
AT337355B (de) 1977-06-27
GB1448419A (en) 1976-09-08
JPS5071895A (cs) 1975-06-14
DK571674A (cs) 1975-06-23
IN138712B (cs) 1976-03-20

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