CA1030524A - Modification synthetique des inhibiteurs trpsine et methode de preparation - Google Patents

Modification synthetique des inhibiteurs trpsine et methode de preparation

Info

Publication number
CA1030524A
CA1030524A CA208,541A CA208541A CA1030524A CA 1030524 A CA1030524 A CA 1030524A CA 208541 A CA208541 A CA 208541A CA 1030524 A CA1030524 A CA 1030524A
Authority
CA
Canada
Prior art keywords
preparing
trypsin inhibitors
synthetically modified
modified trypsin
synthetically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA208,541A
Other languages
English (en)
Other versions
CA208541S (en
Inventor
Wolfgang Konig
Gerhard Guthohrlein
Oswald Zwisler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19732344886 external-priority patent/DE2344886C3/de
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1030524A publication Critical patent/CA1030524A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units
CA208,541A 1973-09-06 1974-09-05 Modification synthetique des inhibiteurs trpsine et methode de preparation Expired CA1030524A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732344886 DE2344886C3 (de) 1973-09-06 Synthetisch modifizierte Derivate des basischen Trypsin-Kalllkrein-Inhibitors aus Säugetierorganen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
CA1030524A true CA1030524A (fr) 1978-05-02

Family

ID=5891765

Family Applications (1)

Application Number Title Priority Date Filing Date
CA208,541A Expired CA1030524A (fr) 1973-09-06 1974-09-05 Modification synthetique des inhibiteurs trpsine et methode de preparation

Country Status (12)

Country Link
US (1) US3953417A (fr)
JP (1) JPS5052081A (fr)
AT (1) AT339472B (fr)
BE (1) BE819639A (fr)
CA (1) CA1030524A (fr)
CH (1) CH608787A5 (fr)
EG (1) EG11583A (fr)
ES (1) ES429700A1 (fr)
FR (1) FR2242992B1 (fr)
GB (1) GB1462493A (fr)
NL (1) NL7411563A (fr)
SE (1) SE414172B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992529A (en) * 1973-09-06 1976-11-16 Hoechst Aktiengesellschaft Method of treating excessive fibrinolysis with synthetically modified trypsin inhibitors
DE3135541A1 (de) * 1981-09-08 1983-03-24 Bayer Ag, 5090 Leverkusen Kallikrein-trypsin-inhibitor-(bpti)-derivate, traegergebundene bpti-derivate, ihre herstellung und ihre verwendung zur herstellung der reinen enzyme trypsin, chymotrypsin und kallikrein
WO2007099650A1 (fr) * 2006-03-01 2007-09-07 Fukuoka Prefectural Government Vecteur contenant un lipide peptidique et procede permettant d'introduire un compose dans des cellules l'utilisant
US9365634B2 (en) * 2007-05-29 2016-06-14 Angiochem Inc. Aprotinin-like polypeptides for delivering agents conjugated thereto to tissues
CA2989400A1 (fr) 2015-06-15 2016-12-22 Angiochem Inc. Ang1005 pour le traitement de la carcinomatose leptomeningee

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1252364B (de) * 1966-02-23 1967-10-19 Farbenfabriken Bayer Aktienge Seilschaft, I everkusen Verfah ren zur Gewinnung des Kallikrem Inakti vators in kristallisierter Form
DE1670897B2 (de) * 1967-07-26 1974-11-21 Bayer Ag, 5090 Leverkusen Polypeptidyl-Kallikrein-Inhibitoren und ein Verfahren zu ihrer Herstellung
US3847893A (en) * 1972-03-01 1974-11-12 Bayer Ag Process for the preparation of insulin derivatives cross-linked by a dicarboxylic acid group at the amino a-1 glycine and amino b-29 lysine

Also Published As

Publication number Publication date
GB1462493A (en) 1977-01-26
US3953417A (en) 1976-04-27
FR2242992A1 (fr) 1975-04-04
AU7296374A (en) 1976-03-11
BE819639A (fr) 1975-03-06
NL7411563A (nl) 1975-03-10
SE7411157L (fr) 1975-03-07
EG11583A (en) 1978-03-29
FR2242992B1 (fr) 1980-01-11
CH608787A5 (fr) 1979-01-31
ES429700A1 (es) 1977-03-01
ATA716374A (de) 1977-02-15
SE414172B (sv) 1980-07-14
JPS5052081A (fr) 1975-05-09
DE2344886B2 (de) 1976-08-12
AT339472B (de) 1977-10-25
DE2344886A1 (de) 1975-04-03

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