CA1024521A - Derives amines de 2,2-diaryl-cyclopropane - Google Patents

Derives amines de 2,2-diaryl-cyclopropane

Info

Publication number
CA1024521A
CA1024521A CA186,433A CA186433A CA1024521A CA 1024521 A CA1024521 A CA 1024521A CA 186433 A CA186433 A CA 186433A CA 1024521 A CA1024521 A CA 1024521A
Authority
CA
Canada
Prior art keywords
formule
dans
est
revendication
groupe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA186,433A
Other languages
English (en)
Other versions
CA186433S (en
Inventor
Jean-Claude Cognacq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexachimie SA
Original Assignee
Hexachimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexachimie SA filed Critical Hexachimie SA
Application granted granted Critical
Publication of CA1024521A publication Critical patent/CA1024521A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

B R E V E T D ' I N V E N T I O N
Dérives aminés de 2,2-diaryl-cyclopropane.
Invention : Jean-Claude COGNACQ
Société Anonyme dite : HEXACHIMIE
ABREGE DESCRIPTIF
La présente invention concerne en tant que produits industriels nouveaux les composés de formule générale :

(I) dans laquelle : R représente l'atome d'hydrogène, un atome d'halogène, un groupe alkyle inférieur ou un groupe alkoxy inférieur ; R1 représente l'atome d'hydrogène, un groupe alkyle inférieur, de préférence méthyle, ou un groupe aralkyle; A représente un groupe alkylène; et R0 représente l'atome d'hydrogène ou un groupe acyle;
et leurs sels d'addition d'acides.
Ces nouveaux produits sont utiles dans le traitement des troubles cardiaques.
CA186,433A 1972-11-30 1973-11-21 Derives amines de 2,2-diaryl-cyclopropane Expired CA1024521A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5527772A GB1409569A (en) 1972-11-30 1972-11-30 Amino derivatives of 2,2-diarylcyclopropane

Publications (1)

Publication Number Publication Date
CA1024521A true CA1024521A (fr) 1978-01-17

Family

ID=10473459

Family Applications (1)

Application Number Title Priority Date Filing Date
CA186,433A Expired CA1024521A (fr) 1972-11-30 1973-11-21 Derives amines de 2,2-diaryl-cyclopropane

Country Status (18)

Country Link
US (1) US3941833A (fr)
AR (1) AR203830A1 (fr)
AT (1) AT328423B (fr)
BE (1) BE807628A (fr)
CA (1) CA1024521A (fr)
CH (1) CH583175A5 (fr)
CS (1) CS186254B2 (fr)
DD (1) DD109861A5 (fr)
DE (1) DE2359796A1 (fr)
DK (1) DK136152B (fr)
ES (1) ES421015A1 (fr)
FR (1) FR2208662B1 (fr)
GB (1) GB1409569A (fr)
HU (1) HU168932B (fr)
NL (1) NL7316485A (fr)
NO (1) NO138562C (fr)
SE (1) SE397826B (fr)
SU (1) SU637077A3 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123247A (fr) * 1974-08-15 1976-02-24 Sumitomo Chemical Co
US4103030A (en) * 1974-12-11 1978-07-25 Sumitomo Chemical Company, Limited Novel cyclopropylmethylamine derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098076A (en) * 1958-08-26 1963-07-16 Burroughs Wellcome Co 1, 1-diphenyl-2-tertiary aminomethyl-3-hydroxy methyl-cyclopropanes and esters thereof
FR2171947A1 (en) * 1972-02-16 1973-09-28 Hexachimie Substd aminomethyl -2,2- diaryl cyclopropanes - for treating anxiety and cardiac insufficiency

Also Published As

Publication number Publication date
AR203830A1 (es) 1975-10-31
FR2208662B1 (fr) 1976-09-03
DD109861A5 (fr) 1974-11-20
GB1409569A (en) 1975-10-08
DE2359796A1 (de) 1974-06-12
NO138562B (no) 1978-06-19
DK136152B (da) 1977-08-22
NO138562C (no) 1978-09-27
CH583175A5 (fr) 1976-12-31
DK136152C (fr) 1978-01-23
CS186254B2 (en) 1978-11-30
NL7316485A (fr) 1974-06-04
SE397826B (sv) 1977-11-21
SU637077A3 (ru) 1978-12-05
BE807628A (fr) 1974-03-15
FR2208662A1 (fr) 1974-06-28
US3941833A (en) 1976-03-02
ATA996073A (de) 1975-06-15
ES421015A1 (es) 1976-07-16
HU168932B (fr) 1976-08-28
AT328423B (de) 1976-03-25

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