CA1024424A - Method and apparatus for quantitative analysis utilizing particulate reagent material - Google Patents

Method and apparatus for quantitative analysis utilizing particulate reagent material

Info

Publication number
CA1024424A
CA1024424A CA200,643A CA200643A CA1024424A CA 1024424 A CA1024424 A CA 1024424A CA 200643 A CA200643 A CA 200643A CA 1024424 A CA1024424 A CA 1024424A
Authority
CA
Canada
Prior art keywords
quantitative analysis
reagent material
analysis utilizing
particulate reagent
utilizing particulate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA200,643A
Other languages
English (en)
French (fr)
Inventor
Alexander M. Saunders
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Application granted granted Critical
Publication of CA1024424A publication Critical patent/CA1024424A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/966—Chemistry: molecular biology and microbiology involving an enzyme system with high turnover rate or complement magnified assay, e.g. multi-enzyme systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA200,643A 1973-06-08 1974-05-23 Method and apparatus for quantitative analysis utilizing particulate reagent material Expired CA1024424A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US368406A US3925018A (en) 1973-06-08 1973-06-08 Method and apparatus for quantitative analysis utilizing particulate reagent material

Publications (1)

Publication Number Publication Date
CA1024424A true CA1024424A (en) 1978-01-17

Family

ID=23451070

Family Applications (1)

Application Number Title Priority Date Filing Date
CA200,643A Expired CA1024424A (en) 1973-06-08 1974-05-23 Method and apparatus for quantitative analysis utilizing particulate reagent material

Country Status (11)

Country Link
US (1) US3925018A (ja)
JP (1) JPS6112223B2 (ja)
BE (1) BE815426A (ja)
CA (1) CA1024424A (ja)
CH (1) CH569970A5 (ja)
DE (1) DE2427221C3 (ja)
FR (1) FR2232757B1 (ja)
GB (1) GB1475608A (ja)
IT (1) IT1020632B (ja)
NL (1) NL7407719A (ja)
SE (1) SE414973B (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201763A (en) * 1975-10-09 1980-05-06 Bio-Rad Laboratories, Inc. Solid phase immunofluorescent assay method
GB1575805A (en) * 1976-03-12 1980-10-01 Technicon Instr Automatic diagnostic apparatus
AT357272B (de) * 1976-09-18 1980-06-25 Boehringer Mannheim Gmbh Verfahren und vorrichtung zum nachweis und zur bestimmung eines spezifischen bindeproteins oder einer damit bindefaehigen substanz
US4191739A (en) * 1977-10-17 1980-03-04 General Electric Company Antigen-antibody reaction assay employing particle aggregation and resistive pulse analysis
US4247647A (en) * 1978-03-14 1981-01-27 Technicon Instruments Corporation Apparatus for the quantitative determination of saccharides
US4242446A (en) * 1978-07-26 1980-12-30 Coulter Electronics, Inc. Method for determining a substance in a biological fluid and reagent combination for use in the method
US4277560A (en) * 1978-10-24 1981-07-07 Technicon Instruments Corporation Enzyme immunoassays using immobilized reagents in a flowing stream
US4223005A (en) * 1979-02-15 1980-09-16 University Of Illinois Foundation Antibody coated bacteria
DE2918342A1 (de) * 1979-05-07 1980-11-20 Behringwerke Ag Latex-reagenz
US4254096A (en) * 1979-10-04 1981-03-03 Bio-Rad Laboratories, Inc. Reagent combination for solid phase immunofluorescent assay
US4476231A (en) * 1981-07-22 1984-10-09 International Remote Imaging Systems, Inc. Method of analyzing the distribution of a reagent between particles and liquid in a suspension
US4610544A (en) * 1981-09-09 1986-09-09 Clifford Riley Flow analysis
US4486097A (en) * 1981-09-09 1984-12-04 E. I. Du Pont De Nemours & Company, Inc. Flow analysis
GB2125547B (en) * 1982-07-31 1986-04-23 Mochida Pharm Co Ltd Simultaneous immunoassay of two or more substances
US4695431A (en) * 1982-08-16 1987-09-22 Technicon Instruments Corporation Volumetric pumping apparatus and method for supplying fluids to sheath stream flow cells
US4683212A (en) * 1982-09-30 1987-07-28 Technicon Instruments Corporation Random access single channel sheath stream apparatus
JPS6081074A (ja) * 1983-10-13 1985-05-09 菊水化学工業株式会社 発泡モルタル用組成物
US5223398A (en) * 1987-03-13 1993-06-29 Coulter Corporation Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics
CA1339840C (en) * 1988-12-16 1998-04-28 Kenneth Kortright Method and apparatus for screening cells or formed bodies with populations expressing selected characteristics
GB9405028D0 (en) * 1994-03-15 1994-04-27 Counting Tech Ltd Fluid diluter
US5981180A (en) * 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
US6784981B1 (en) 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
WO2003027678A1 (en) * 2001-09-26 2003-04-03 Psychiatric Genomics, Inc. Fluorescence proximity assay
US20030092008A1 (en) * 2001-11-14 2003-05-15 Bell Michael L. Method and apparatus for multiplex flow cytometry analysis of diverse mixed analytes from bodily fluid samples
US20040038318A1 (en) * 2002-08-23 2004-02-26 Bell Michael L. Creatine kinase isoenzyme determination in multiplexed assays
US20070238140A1 (en) * 2006-04-07 2007-10-11 Pentoney Stephen L Jr Method For Multiplex Bead-Based Assays Using Chemiluminescence and Fluorescence
CN101542273B (zh) * 2006-08-24 2011-01-26 新加坡科技研究局 紧凑式光学检测系统
US10942126B2 (en) * 2018-05-17 2021-03-09 S2 Detection Nevada, Inc. Portable liquid analyzer
JP7191975B2 (ja) 2018-03-30 2022-12-19 アイデックス ラボラトリーズ インコーポレイテッド フローサイトメータ、そのレーザ光学アセンブリ、およびレーザ光学アセンブリの組立方法
CN111630280A (zh) 2018-04-04 2020-09-04 三菱重工发动机和增压器株式会社 离心压缩机以及具备该离心压缩机的涡轮增压器
EP4425235A2 (en) 2020-06-17 2024-09-04 IDEXX Laboratories, Inc. Flow cytometer and laser optics assembly thereof
CN111811999B (zh) * 2020-06-17 2023-06-20 杭州协合医疗用品有限公司 一种测定交联透明质酸钠凝胶中包裹的交联葡聚糖微球粒径的方法
CN115078324B (zh) * 2022-06-30 2023-03-10 嘉兴市唯真生物科技有限公司 一种高通量流式荧光检测方法、智能终端及存储介质

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2379158A (en) * 1943-02-03 1945-06-26 Westinghouse Electric Corp Particle size determination
US2875666A (en) * 1953-07-13 1959-03-03 Ohio Commw Eng Co Method of simultaneously counting red and white blood cells
US3088875A (en) * 1959-10-27 1963-05-07 Hyland Lab Immunological diagnostics utilizing polystyrene latex particles of 0.15 to 0.25 micron
US3275834A (en) * 1963-04-01 1966-09-27 Daniel S Stevens Apparatus for analyzing the size and number of particles in suspension
US3247078A (en) * 1963-10-30 1966-04-19 Union Carbide Corp Process for the propagation of microorganisms using a matrix of poly
US3492396A (en) * 1967-03-13 1970-01-27 Becton Dickinson Co Agglutinate separation method and apparatus
US3794467A (en) * 1971-10-28 1974-02-26 Du Pont Removing substances from a liquid by precipitation in porous glass beads

Also Published As

Publication number Publication date
US3925018A (en) 1975-12-09
FR2232757A1 (ja) 1975-01-03
AU6975274A (en) 1975-12-04
JPS5033890A (ja) 1975-04-01
FR2232757B1 (ja) 1978-12-01
GB1475608A (en) 1977-06-01
DE2427221B2 (de) 1978-01-05
SE414973B (sv) 1980-08-25
NL7407719A (ja) 1974-12-10
SE7407551L (ja) 1974-12-09
BE815426A (fr) 1974-11-22
IT1020632B (it) 1977-12-30
DE2427221A1 (de) 1975-01-02
DE2427221C3 (de) 1978-09-14
JPS6112223B2 (ja) 1986-04-07
CH569970A5 (ja) 1975-11-28

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