CA1024149A - 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES - Google Patents

4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES

Info

Publication number
CA1024149A
CA1024149A CA176,763A CA176763A CA1024149A CA 1024149 A CA1024149 A CA 1024149A CA 176763 A CA176763 A CA 176763A CA 1024149 A CA1024149 A CA 1024149A
Authority
CA
Canada
Prior art keywords
decahydroisoquinolines
trans
aryl
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA176,763A
Other languages
English (en)
French (fr)
Other versions
CA176763S (en
Inventor
David R. Brittelli
William C. Ripka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of CA1024149A publication Critical patent/CA1024149A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA176,763A 1972-07-20 1973-07-18 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES Expired CA1024149A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27380672A 1972-07-20 1972-07-20
US36584373A 1973-06-01 1973-06-01

Publications (1)

Publication Number Publication Date
CA1024149A true CA1024149A (en) 1978-01-10

Family

ID=26956443

Family Applications (1)

Application Number Title Priority Date Filing Date
CA176,763A Expired CA1024149A (en) 1972-07-20 1973-07-18 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES

Country Status (13)

Country Link
JP (1) JPS4985075A (sv)
AR (1) AR208650A1 (sv)
CA (1) CA1024149A (sv)
DE (2) DE2351599A1 (sv)
ES (1) ES417127A1 (sv)
FR (1) FR2193600B1 (sv)
GB (2) GB1436377A (sv)
HU (1) HU167738B (sv)
IE (1) IE37929B1 (sv)
IL (3) IL48667A (sv)
LU (1) LU68066A1 (sv)
NL (1) NL7310078A (sv)
SE (1) SE7602150L (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7509337L (sv) * 1974-09-23 1976-03-24 Du Pont Smertstillande foreningar
PT68934A (en) * 1977-12-27 1979-01-01 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines
CA2224047A1 (en) * 1990-06-05 1991-12-06 Toray Industries, Inc. Indole derivatives
WO1993001186A1 (en) * 1991-07-05 1993-01-21 Smithkline Beecham Farmaceutici S.P.A. Hydroisoquinoline derivatives
IT1307327B1 (it) * 1995-09-12 2001-10-30 Smithkline Beecham Spa Derivati idroisochinolinici sostituiti

Also Published As

Publication number Publication date
DE2351599A1 (de) 1974-01-31
JPS4985075A (sv) 1974-08-15
GB1436377A (en) 1976-05-19
IE37929L (en) 1974-01-20
IL42790A0 (en) 1973-10-25
IL48667A (en) 1976-11-30
GB1436376A (en) 1976-05-19
IE37929B1 (en) 1977-11-09
FR2193600A1 (sv) 1974-02-22
SE7602150L (sv) 1976-02-23
HU167738B (sv) 1975-12-25
FR2193600B1 (sv) 1976-10-22
ES417127A1 (es) 1976-04-01
AR208650A1 (es) 1977-02-28
IL42790A (en) 1976-11-30
AU5820773A (en) 1975-01-23
LU68066A1 (sv) 1973-09-26
NL7310078A (sv) 1974-01-22
DE2336559A1 (de) 1974-01-31
IL48667A0 (en) 1976-02-29

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