CA1005057A - Imidazolo-as-triazines - Google Patents
Imidazolo-as-triazinesInfo
- Publication number
- CA1005057A CA1005057A CA189,199A CA189199A CA1005057A CA 1005057 A CA1005057 A CA 1005057A CA 189199 A CA189199 A CA 189199A CA 1005057 A CA1005057 A CA 1005057A
- Authority
- CA
- Canada
- Prior art keywords
- imidazolo
- triazines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AIMBMQACKYCWKB-UHFFFAOYSA-N 7h-imidazo[4,5-e][1,2,4]triazine Chemical class C1=NN=C2NC=NC2=N1 AIMBMQACKYCWKB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB55373*[A GB1457873A (en) | 1973-01-04 | 1973-01-04 | Imidazotriazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1005057A true CA1005057A (en) | 1977-02-08 |
Family
ID=9706420
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA189,199A Expired CA1005057A (en) | 1973-01-04 | 1973-12-28 | Imidazolo-as-triazines |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3941785A (instruction) |
| JP (1) | JPS4995994A (instruction) |
| AT (1) | AT336029B (instruction) |
| AU (1) | AU474078B2 (instruction) |
| BE (1) | BE809369A (instruction) |
| CA (1) | CA1005057A (instruction) |
| CH (1) | CH618170A5 (instruction) |
| DE (1) | DE2364076A1 (instruction) |
| ES (1) | ES422001A1 (instruction) |
| FI (2) | FI57260C (instruction) |
| FR (1) | FR2213058B1 (instruction) |
| GB (1) | GB1457873A (instruction) |
| IE (1) | IE38681B1 (instruction) |
| IL (1) | IL43872A (instruction) |
| LU (1) | LU69099A1 (instruction) |
| NL (1) | NL7400095A (instruction) |
| NO (1) | NO140301C (instruction) |
| SE (1) | SE408179B (instruction) |
| ZA (1) | ZA739534B (instruction) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
| US4107309A (en) * | 1977-05-23 | 1978-08-15 | American Cyanamid Company | Substituted imidazo[1,2-d]-as-triazines |
| US4096257A (en) * | 1977-05-23 | 1978-06-20 | American Cyanamid Company | Substituted imidazo [1,2-d]-as-triazines |
| US4126444A (en) * | 1977-11-22 | 1978-11-21 | American Cynamid Company | Substituted imidazo (1,5-D)-as-triazin-4-ols, and herbicidal use thereof |
| US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
| DD244681A3 (de) * | 1985-12-02 | 1987-04-15 | Zeiss Jena Veb Carl | Vorrichtung zur positionierung von enden flexibler lichtleitelemente |
| US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
| HU227841B1 (en) | 1997-11-12 | 2012-05-02 | Bayer Pharma AG | 2-phenyl substituted imidazotriazinones, process for their preparation and pharmaceutical compositions thereof |
| DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
| CN1314811A (zh) | 1998-08-26 | 2001-09-26 | 史密丝克莱恩比彻姆公司 | 治疗肺病的方法 |
| TR200909479T2 (tr) | 1999-08-21 | 2012-02-21 | Nycomed Gmbh | Sinerjistik kombinasyon. |
| WO2002089808A1 (de) * | 2001-05-09 | 2002-11-14 | Bayer Healthcare Ag | Neue verwendung von 2-phenyl-substituierten imidazotriazinonen |
| GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
| GB0113344D0 (en) | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
| DE10130167A1 (de) * | 2001-06-22 | 2003-01-02 | Bayer Ag | Imidazotriazine |
| DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| DE10230605A1 (de) * | 2002-07-08 | 2004-01-29 | Bayer Ag | Substituierte Imidazotriazine |
| DE10230604A1 (de) * | 2002-07-08 | 2004-01-29 | Bayer Ag | Heterocyclisch substituierte Imidazotriazine |
| DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| JP2006522127A (ja) * | 2003-04-01 | 2006-09-28 | スミスクライン ビーチャム コーポレーション | イミダゾトリアジン化合物 |
| DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
| DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
| DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| AU2006299232A1 (en) * | 2005-09-29 | 2007-04-12 | Bayer Schering Pharma Aktiengesellschaft | PDE inhibitors and combinations thereof for the treatment of urological disorders |
| EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20070244143A1 (en) * | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | アンジオテンシン調節による神経新生 |
| AU2007249435A1 (en) * | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
| AU2007292848A1 (en) * | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| CA2663347A1 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Ppar mediated modulation of neurogenesis |
| CN101711153A (zh) * | 2007-06-13 | 2010-05-19 | 拜耳先灵制药股份公司 | 用于治疗听觉损伤的pde抑制剂 |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US20150119399A1 (en) | 2012-01-10 | 2015-04-30 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791025A (fr) * | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
-
1973
- 1973-01-04 GB GB55373*[A patent/GB1457873A/en not_active Expired
- 1973-12-18 FI FI3900/73A patent/FI57260C/fi active
- 1973-12-18 NO NO4843/73A patent/NO140301C/no unknown
- 1973-12-18 ZA ZA739534A patent/ZA739534B/xx unknown
- 1973-12-19 AU AU63774/73A patent/AU474078B2/en not_active Expired
- 1973-12-20 IL IL43872A patent/IL43872A/xx unknown
- 1973-12-21 DE DE2364076A patent/DE2364076A1/de not_active Withdrawn
- 1973-12-26 US US05/427,558 patent/US3941785A/en not_active Expired - Lifetime
- 1973-12-28 FR FR7346979A patent/FR2213058B1/fr not_active Expired
- 1973-12-28 CA CA189,199A patent/CA1005057A/en not_active Expired
- 1973-12-31 IE IE2345/73A patent/IE38681B1/xx unknown
- 1973-12-31 JP JP49004782A patent/JPS4995994A/ja active Pending
-
1974
- 1974-01-02 AT AT2374A patent/AT336029B/de not_active IP Right Cessation
- 1974-01-02 LU LU69099A patent/LU69099A1/xx unknown
- 1974-01-02 CH CH9274A patent/CH618170A5/de not_active IP Right Cessation
- 1974-01-03 BE BE139496A patent/BE809369A/xx unknown
- 1974-01-03 SE SE7400062A patent/SE408179B/xx unknown
- 1974-01-03 ES ES422001A patent/ES422001A1/es not_active Expired
- 1974-01-04 NL NL7400095A patent/NL7400095A/xx not_active Application Discontinuation
-
1979
- 1979-10-10 FI FI793137A patent/FI793137A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2364076A1 (de) | 1974-07-18 |
| GB1457873A (en) | 1976-12-08 |
| BE809369A (fr) | 1974-07-03 |
| FI793137A7 (fi) | 1981-01-01 |
| JPS4995994A (instruction) | 1974-09-11 |
| IL43872A0 (en) | 1974-03-14 |
| SE408179B (sv) | 1979-05-21 |
| IE38681B1 (en) | 1978-05-10 |
| ATA2374A (de) | 1976-08-15 |
| US3941785A (en) | 1976-03-02 |
| IL43872A (en) | 1979-01-31 |
| ZA739534B (en) | 1974-11-27 |
| IE38681L (en) | 1974-07-04 |
| NL7400095A (instruction) | 1974-07-08 |
| CH618170A5 (instruction) | 1980-07-15 |
| AT336029B (de) | 1977-04-12 |
| NO140301C (no) | 1979-08-08 |
| ES422001A1 (es) | 1976-08-01 |
| FR2213058B1 (instruction) | 1977-07-01 |
| AU6377473A (en) | 1975-06-19 |
| NO140301B (no) | 1979-04-30 |
| LU69099A1 (instruction) | 1974-04-02 |
| FI57260B (fi) | 1980-03-31 |
| FR2213058A1 (instruction) | 1974-08-02 |
| AU474078B2 (en) | 1976-07-15 |
| FI57260C (fi) | 1980-07-10 |
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