BRPI0920868A2 - captura de partículas - Google Patents

captura de partículas

Info

Publication number
BRPI0920868A2
BRPI0920868A2 BRPI0920868A BRPI0920868A BRPI0920868A2 BR PI0920868 A2 BRPI0920868 A2 BR PI0920868A2 BR PI0920868 A BRPI0920868 A BR PI0920868A BR PI0920868 A BRPI0920868 A BR PI0920868A BR PI0920868 A2 BRPI0920868 A2 BR PI0920868A2
Authority
BR
Brazil
Prior art keywords
particle capture
capture
particle
Prior art date
Application number
BRPI0920868A
Other languages
English (en)
Inventor
Chia-Hsien Hsu
Mehmet Toner
Shannon Stott
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of BRPI0920868A2 publication Critical patent/BRPI0920868A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70514—CD4
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70517—CD8

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
BRPI0920868A 2008-09-26 2009-09-25 captura de partículas BRPI0920868A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10042008P 2008-09-26 2008-09-26
PCT/US2009/058408 WO2010036912A2 (en) 2008-09-26 2009-09-25 Capturing particles

Publications (1)

Publication Number Publication Date
BRPI0920868A2 true BRPI0920868A2 (pt) 2015-12-22

Family

ID=42060400

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0920868A BRPI0920868A2 (pt) 2008-09-26 2009-09-25 captura de partículas

Country Status (6)

Country Link
US (3) US9128091B2 (pt)
EP (1) EP2344883A4 (pt)
JP (1) JP2012504243A (pt)
CN (1) CN102227637A (pt)
BR (1) BRPI0920868A2 (pt)
WO (1) WO2010036912A2 (pt)

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CN102227637A (zh) 2008-09-26 2011-10-26 通用医疗公司 捕获粒子
WO2012037030A2 (en) 2010-09-14 2012-03-22 The Regents Of The University Of California Method and device for isolating cells from heterogeneous solution using microfluidic trapping vortices
CN103477222B (zh) * 2010-09-29 2016-08-10 麻省理工学院 用于高通量研究细胞相互作用的装置
US9417244B2 (en) 2011-09-28 2016-08-16 The General Hospital Corporation Cadherins as cancer biomarkers
JP2015506674A (ja) 2011-12-07 2015-03-05 サイトベラ， インコーポレイテッド 試料処理のための方法および装置
JP5742728B2 (ja) * 2012-01-06 2015-07-01 コニカミノルタ株式会社 細胞分離デバイスおよびこれを用いた細胞分離方法
US20150285717A1 (en) 2012-05-29 2015-10-08 The Regents Of The University Of California Systems, methods and components for isolating cells from a fluid sample
CN102719353B (zh) * 2012-06-13 2014-07-30 湖南大学 一种用于外周血中循环癌细胞的特异性捕获的装置及方法
SG11201505411RA (en) * 2013-01-24 2015-08-28 Univ Singapore Microdevices for separation of non-spherical particles and applications thereof
US9138746B2 (en) 2013-05-01 2015-09-22 Honeywell International Inc. Fluid stop for measured sample containment
KR101508974B1 (ko) * 2013-05-14 2015-04-07 한국과학기술연구원 종양 세포의 검출장치 및 검출방법
US11262361B2 (en) 2013-07-18 2022-03-01 The General Hospital Corporation Selective capture and release of rare mammalian cells using photodegradable hydrogels in a microfluidic platform
FI128658B (en) * 2013-11-24 2020-09-30 Kemira Oyj Method and system for analysis of a sample containing solid particles and use of the method and system
EP3100783A4 (en) 2014-01-31 2017-09-27 Alps Electric Co., Ltd. Flow channel plate
KR101515394B1 (ko) * 2014-06-09 2015-05-04 연세대학교 산학협력단 세포 용해 미세유체 장치 및 이를 이용한 세포 용해 방법
WO2015200857A1 (en) 2014-06-27 2015-12-30 The Regents Of The University Of California Apparatus and method for label-free analysis of rare cells from bodily fluids
CN104087506B (zh) * 2014-07-08 2016-02-24 西安交通大学 一种高通量单细胞反转录pcr分析装置
EP3177904A4 (en) * 2014-08-07 2018-01-03 The General Hospital Corporation Platelet-targeted microfluidic isolation of cells
WO2016164359A1 (en) * 2015-04-10 2016-10-13 Tumorgen Mdx Llc Rare cell isolation device and method of use thereof
TWI591341B (zh) * 2016-05-13 2017-07-11 亞諾法生技股份有限公司 微流道裝置
US11602747B2 (en) 2016-05-22 2023-03-14 Cornell University Multifunctional microfluidic device for capturing target cells and analyzing genomic DNA isolated from the target cells while under flow conditions
US10717086B2 (en) 2016-08-29 2020-07-21 The Regents Of The University Of California Integrated system for isolation and emulsification of particles and cells
KR101872780B1 (ko) * 2017-01-24 2018-06-29 광주과학기술원 헤링본 타입 유체유도유닛 및 이를 이용한 세포 농축 장치
US10434510B2 (en) 2017-05-06 2019-10-08 International Business Machines Corporation Microfluidic probe with bypass and control channels
WO2018213847A1 (en) * 2017-05-19 2018-11-22 The General Hospital Corporation Engineered nano-interfaces for microfluidic isolation of extracellular vesicles
US10730042B2 (en) * 2017-06-30 2020-08-04 Ce Biotechnology, Inc. Biological detection system
US20200224140A1 (en) * 2017-07-14 2020-07-16 Cedars-Sinai Medical Center L-glass: a novel functionalization method for covalently attaching ecm protein to optical glass
CN108103022A (zh) 2017-12-15 2018-06-01 京东方科技集团股份有限公司 一种目标物捕获装置
CN108554326A (zh) * 2018-03-02 2018-09-21 四川大学 一种用于c4烷基化反应的毫米级小通道反应器
IT201800006083A1 (it) * 2018-06-06 2019-12-06 Dispositivo microfluidico per la concentrazione di particelle tramite centrifugazione, e relativo dispositivo di centrifugazione e/o rilevazione
KR102057788B1 (ko) 2018-07-26 2019-12-19 재단법인 다차원 스마트 아이티 융합시스템 연구단 수력학적 도약 현상을 이용한 연속적 침강 기반 미세유체 분리 및 배양 시스템 및 방법
JP7195538B2 (ja) * 2019-03-15 2022-12-26 国立大学法人東海国立大学機構 デバイスの製造方法、および、デバイス
US20210060229A1 (en) * 2019-09-04 2021-03-04 The Regents Of The University Of Michigan Office Of Technology Transfer Indwelling intravascular aphaeretic system for in vivo enrichment of circulating tumor cells
CN116024067A (zh) * 2022-12-19 2023-04-28 深圳职业技术学院 一种循环胎儿细胞分离装置及其制备方法

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Also Published As

Publication number Publication date
US20110294187A1 (en) 2011-12-01
CN102227637A (zh) 2011-10-26
WO2010036912A3 (en) 2010-07-01
JP2012504243A (ja) 2012-02-16
WO2010036912A2 (en) 2010-04-01
US20190072465A1 (en) 2019-03-07
EP2344883A2 (en) 2011-07-20
US10126218B2 (en) 2018-11-13
US9128091B2 (en) 2015-09-08
EP2344883A4 (en) 2012-03-21
US20150377753A1 (en) 2015-12-31

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]